ATM localization and heterochromatin repair depend on direct interaction of the 53BP1-BRCT2 domain with γH2AX RA Baldock, M Day, OJ Wilkinson, R Cloney, PA Jeggo, AW Oliver, ... Cell reports 13 (10), 2081-2089, 2015 | 78 | 2015 |
Atl1 regulates choice between global genome and transcription-coupled repair of O6-alkylguanines VF Latypov, JL Tubbs, AJ Watson, AS Marriott, G McGown, M Thorncroft, ... Molecular cell 47 (1), 50-60, 2012 | 46 | 2012 |
The nitrosated bile acid DNA lesion O6 -carboxymethylguanine is a substrate for the human DNA repair protein O6 -methylguanine … P Senthong, CL Millington, OJ Wilkinson, AS Marriott, AJ Watson, ... Nucleic acids research 41 (5), 3047-3055, 2013 | 38 | 2013 |
Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation–π interactions OJ Wilkinson, V Latypov, JL Tubbs, CL Millington, R Morita, H Blackburn, ... Proceedings of the National Academy of Sciences 109 (46), 18755-18760, 2012 | 27 | 2012 |
CtIP forms a tetrameric dumbbell-shaped particle which bridges complex DNA end structures for double-strand break repair OJ Wilkinson, A Martín-González, H Kang, SJ Northall, DB Wigley, ... Elife 8, e42129, 2019 | 23 | 2019 |
Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing pyrimidine transition mutations F Zhang, M Tsunoda, K Suzuki, Y Kikuchi, O Wilkinson, CL Millington, ... Nucleic acids research 41 (10), 5524-5532, 2013 | 23 | 2013 |
Human HELB is a processive motor protein that catalyzes RPA clearance from single-stranded DNA S Hormeno, OJ Wilkinson, C Aicart-Ramos, S Kuppa, E Antony, ... Proceedings of the National Academy of Sciences 119 (15), e2112376119, 2022 | 22 | 2022 |
Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub M Wilkinson, OJ Wilkinson, C Feyerherm, EE Fletcher, DB Wigley, ... Elife 11, e83409, 2022 | 15 | 2022 |
A stapled peptide mimetic of the CtIP tetramerization motif interferes with double-strand break repair and replication fork protection A Kuster, NL Mozaffari, OJ Wilkinson, JL Wojtaszek, C Zurfluh, ... Science Advances 7 (8), eabc6381, 2021 | 12 | 2021 |
The molecular basis of protein toxin HicA–dependent binding of the protein antitoxin HicB to DNA AJ Winter, C Williams, MN Isupov, H Crocker, M Gromova, P Marsh, ... Journal of Biological Chemistry 293 (50), 19429-19440, 2018 | 12 | 2018 |
The S. pombe Translation Initiation Factor eIF4G Is Sumoylated and Associates with the SUMO Protease Ulp2 J Jongjitwimol, M Feng, L Zhou, O Wilkinson, L Small, R Baldock, ... PLoS One 9 (5), e94182, 2014 | 12 | 2014 |
Synthesis of oligodeoxyribonucleotides containing a conformationally-locked anti analogue of O6-methyl-2′-deoxyguanosine and their recognition by MGMT and Atl1 K Abdu, MK Aiertza, OJ Wilkinson, JA Grasby, P Senthong, AC Povey, ... Chemical communications 48 (91), 11214-11216, 2012 | 11 | 2012 |
Targeted control of pneumolysin production by a mobile genetic element in Streptococcus pneumoniae EJ Stevens, DJ Morse, D Bonini, S Duggan, T Brignoli, M Recker, JA Lees, ... Microbial Genomics 8 (4), 000784, 2022 | 9 | 2022 |
Long DNA constructs to study helicases and nucleic acid translocases using optical tweezers C Aicart-Ramos, S Hormeno, OJ Wilkinson, MS Dillingham, ... Methods in Enzymology 673, 311-358, 2022 | 7 | 2022 |
Bulk and single-molecule analysis of a bacterial DNA2-like helicase–nuclease reveals a single-stranded DNA looping motor OJ Wilkinson, C Carrasco, C Aicart-Ramos, F Moreno-Herrero, ... Nucleic Acids Research 48 (14), 7991-8005, 2020 | 7 | 2020 |
Mass Spectrometric Analysis of the Active Site Tryptic Peptide of Recombinant O6-Methylguanine-DNA Methyltransferase Following Incubation with Human Colorectal DNA Reveals the … R Abdelhady, P Senthong, CE Eyers, O Reamtong, E Cowley, ... Chemical research in toxicology 36 (12), 1921-1929, 2023 | 6 | 2023 |
O6-Carboxymethylguanine in DNA forms a sequence context-dependent wobble base-pair structure with thymine F Zhang, M Tsunoda, Y Kikuchi, O Wilkinson, CL Millington, GP Margison, ... Acta Crystallographica Section D: Biological Crystallography 70 (6), 1669-1679, 2014 | 3 | 2014 |
Synthesis of oligodeoxyribonucleotides containing a tricyclic thio analogue of O6-methylguanine and their recognition by MGMT and Atl1 K Abdu, MK Aiertza, OJ Wilkinson, P Senthong, TD Craggs, AC Povey, ... Nucleosides, Nucleotides & Nucleic Acids 39 (8), 1108-1121, 2020 | 1 | 2020 |
DNA binding and bridging by human CtIP in the healthy and diseased states S Lokanathan Balaji, S De Bragança, F Balaguer-Pérez, S Northall, ... Nucleic acids research 52 (14), 8303-8319, 2024 | | 2024 |
Mechanism of DNA entrapment by the MukBEF SMC complex and its inhibition by a viral DNA mimic F Bürmann, B Clifton, S Koekemoer, OJ Wilkinson, D Kimanius, ... bioRxiv, 2024.10. 02.616235, 2024 | | 2024 |