Intra-tumour heterogeneity: a looking glass for cancer? A Marusyk, V Almendro, K Polyak Nature reviews cancer 12 (5), 323-334, 2012 | 2372 | 2012 |
Tumor heterogeneity: causes and consequences A Marusyk, K Polyak Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1805 (1), 105-117, 2010 | 2083 | 2010 |
The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors LLC Marotta, V Almendro, A Marusyk, M Shipitsin, J Schemme, SR Walker, ... The Journal of clinical investigation 121 (7), 2723-2735, 2011 | 1011 | 2011 |
Intratumor heterogeneity: the rosetta stone of therapy resistance A Marusyk, M Janiszewska, K Polyak Cancer cell 37 (4), 471-484, 2020 | 742 | 2020 |
Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity A Marusyk, DP Tabassum, PM Altrock, V Almendro, F Michor, K Polyak Nature 514 (7520), 54-58, 2014 | 662 | 2014 |
Cellular heterogeneity and molecular evolution in cancer V Almendro, A Marusyk, K Polyak Annual Review of Pathology: Mechanisms of Disease 8 (1), 277-302, 2013 | 628 | 2013 |
Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2 TR Lyons, J O'brien, VF Borges, MW Conklin, PJ Keely, KW Eliceiri, ... Nature medicine 17 (9), 1109-1115, 2011 | 409 | 2011 |
Grb2 regulates internalization of EGF receptors through clathrin-coated pits X Jiang, F Huang, A Marusyk, A Sorkin Molecular biology of the cell 14 (3), 858-870, 2003 | 400 | 2003 |
Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity V Almendro, YK Cheng, A Randles, S Itzkovitz, A Marusyk, E Ametller, ... Cell reports 6 (3), 514-527, 2014 | 326 | 2014 |
MSC-regulated microRNAs converge on the transcription factor FOXP2 and promote breast cancer metastasis BG Cuiffo, A Campagne, GW Bell, A Lembo, F Orso, EC Lien, MK Bhasin, ... Cell stem cell 15 (6), 762-774, 2014 | 203 | 2014 |
The 2019 mathematical oncology roadmap RC Rockne, A Hawkins-Daarud, KR Swanson, JP Sluka, JA Glazier, ... Physical biology 16 (4), 041005, 2019 | 195 | 2019 |
Targeting Akt3 signaling in triple-negative breast cancer YR Chin, T Yoshida, A Marusyk, AH Beck, K Polyak, A Toker Cancer research 74 (3), 964-973, 2014 | 176 | 2014 |
Irradiation selects for p53-deficient hematopoietic progenitors A Marusyk, CC Porter, V Zaberezhnyy, J DeGregori PLoS biology 8 (3), e1000324, 2010 | 167 | 2010 |
Fibroblasts and alectinib switch the evolutionary games played by non-small cell lung cancer A Kaznatcheev, J Peacock, D Basanta, A Marusyk, JG Scott Nature ecology & evolution 3 (3), 450-456, 2019 | 152 | 2019 |
Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes A Marusyk, DP Tabassum, M Janiszewska, AE Place, A Trinh, AI Rozhok, ... Cancer research 76 (22), 6495-6506, 2016 | 145 | 2016 |
Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments M Janiszewska, DP Tabassum, Z Castaño, S Cristea, KN Yamamoto, ... Nature cell biology 21 (7), 879-888, 2019 | 143 | 2019 |
Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells LE Tavera-Mendoza, T Westerling, E Libby, A Marusyk, L Cato, R Cassani, ... Proceedings of the National Academy of Sciences 114 (11), E2186-E2194, 2017 | 139 | 2017 |
Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures R Vander Velde, N Yoon, V Marusyk, A Durmaz, A Dhawan, ... Nature communications 11 (1), 2393, 2020 | 113 | 2020 |
Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection? CJ Henry, A Marusyk, J DeGregori Aging (Albany NY) 3 (6), 643, 2011 | 106 | 2011 |
Collateral sensitivity networks reveal evolutionary instability and novel treatment strategies in ALK mutated non-small cell lung cancer A Dhawan, D Nichol, F Kinose, ME Abazeed, A Marusyk, EB Haura, ... Scientific reports 7 (1), 1232, 2017 | 99 | 2017 |