| Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus P Pal, KA Dowd, JD Brien, MA Edeling, S Gorlatov, S Johnson, I Lee, ... PLoS pathogens 9 (4), e1003312, 2013 | 302 | 2013 |
| Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2 S Sukupolvi-Petty, SK Austin, M Engle, JD Brien, KA Dowd, KL Williams, ... Journal of virology 84 (18), 9227-9239, 2010 | 257 | 2010 |
| The development of therapeutic antibodies that neutralize homologous and heterologous genotypes of dengue virus type 1 B Shrestha, JD Brien, S Sukupolvi-Petty, SK Austin, MA Edeling, T Kim, ... PLoS pathogens 6 (4), e1000823, 2010 | 257 | 2010 |
| Zika virus pathogenesis in rhesus macaques is unaffected by pre-existing immunity to dengue virus P Pantoja, EX Pérez-Guzmán, IV Rodríguez, LJ White, O González, ... Nature communications 8 (1), 15674, 2017 | 224 | 2017 |
| SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells T Patra, K Meyer, L Geerling, TS Isbell, DF Hoft, J Brien, AK Pinto, RB Ray, ... PLoS pathogens 16 (12), e1009128, 2020 | 223 | 2020 |
| Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo … K Modjarrad, L Lin, SL George, KE Stephenson, KH Eckels, ... The Lancet 391 (10120), 563-571, 2018 | 213 | 2018 |
| West Nile virus-specific CD4 T cells exhibit direct antiviral cytokine secretion and cytotoxicity and are sufficient for antiviral protection JD Brien, JL Uhrlaub, J Nikolich-Zugich The Journal of Immunology 181 (12), 8568-8575, 2008 | 208 | 2008 |
| Genotype-specific neutralization and protection by antibodies against dengue virus type 3 JD Brien, SK Austin, S Sukupolvi-Petty, KM O'Brien, S Johnson, ... Journal of virology 84 (20), 10630-10643, 2010 | 182 | 2010 |
| Key role of T cell defects in age-related vulnerability to West Nile virus JD Brien, JL Uhrlaub, A Hirsch, CA Wiley, J Nikolich-Žugich Journal of Experimental Medicine 206 (12), 2735-2745, 2009 | 177 | 2009 |
| The interferon-inducible gene viperin restricts West Nile virus pathogenesis KJ Szretter, JD Brien, LB Thackray, HW Virgin, P Cresswell, MS Diamond Journal of virology 85 (22), 11557-11566, 2011 | 174 | 2011 |
| Protective capacity and epitope specificity of CD8+ T cells responding to lethal West Nile virus infection JD Brien, JL Uhrlaub, J Nikolich‐Žugich European journal of immunology 37 (7), 1855-1863, 2007 | 166 | 2007 |
| Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-blind, randomised, placebo-controlled, phase 3 trial AC Kalil, AK Mehta, TF Patterson, N Erdmann, CA Gomez, MK Jain, ... The Lancet Respiratory Medicine 9 (12), 1365-1376, 2021 | 159 | 2021 |
| Isolation and characterization of broad and ultrapotent human monoclonal antibodies with therapeutic activity against chikungunya virus SA Smith, LA Silva, JM Fox, AI Flyak, N Kose, G Sapparapu, ... Cell host & microbe 18 (1), 86-95, 2015 | 155 | 2015 |
| Cytomegalovirus infection impairs immune responses and accentuates T-cell pool changes observed in mice with aging L Cicin-Sain, JD Brien, JL Uhrlaub, A Drabig, TF Marandu, ... Public Library of Science 8 (8), e1002849, 2012 | 155 | 2012 |
| Propagation, quantification, detection, and storage of West Nile virus JD Brien, HM Lazear, MS Diamond Current protocols in microbiology 31 (1), 15D. 3.1-15D. 3.18, 2013 | 145 | 2013 |
| A Temporal Role Of Type I Interferon Signaling in CD8+ T Cell Maturation during Acute West Nile Virus Infection AK Pinto, S Daffis, JD Brien, MD Gainey, WM Yokoyama, KCF Sheehan, ... PLoS pathogens 7 (12), e1002407, 2011 | 137 | 2011 |
| Chikungunya virus infection results in higher and persistent viral replication in aged rhesus macaques due to defects in anti-viral immunity I Messaoudi, J Vomaske, T Totonchy, CN Kreklywich, K Haberthur, ... PLoS neglected tropical diseases 7 (7), e2343, 2013 | 134 | 2013 |
| Activation of virus-specific CD8+ T cells by lipopolysaccharide-induced IL-12 and IL-18 HP Raué, JD Brien, E Hammarlund, MK Slifka The Journal of Immunology 173 (11), 6873-6881, 2004 | 123 | 2004 |
| Interferon Regulatory Factor-1 (IRF-1) Shapes Both Innate and CD8+ T Cell Immune Responses against West Nile Virus Infection JD Brien, S Daffis, HM Lazear, H Cho, MS Suthar, M Gale Jr, MS Diamond PLoS pathogens 7 (9), e1002230, 2011 | 118 | 2011 |
| CD4+T cells mediate protection against Zika associated severe disease in a mouse model of infection M Hassert, KJ Wolf, KE Schwetye, RJ DiPaolo, JD Brien, AK Pinto PLoS pathogens 14 (9), e1007237, 2018 | 107 | 2018 |
