| Inhibition of CRISPR-Cas9 with bacteriophage proteins BJ Rauch, MR Silvis, JF Hultquist, CS Waters, MJ McGregor, NJ Krogan, ... Cell 168 (1), 150-158. e10, 2017 | 529 | 2017 |
| Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection S Jäger, DY Kim, JF Hultquist, K Shindo, RS LaRue, E Kwon, M Li, ... Nature 481 (7381), 371-375, 2012 | 441 | 2012 |
| Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1 JF Hultquist, JA Lengyel, EW Refsland, RS LaRue, L Lackey, WL Brown, ... Journal of virology 85 (21), 11220-11234, 2011 | 415 | 2011 |
| MDA5 governs the innate immune response to SARS-CoV-2 in lung epithelial cells X Yin, L Riva, Y Pu, L Martin-Sancho, J Kanamune, Y Yamamoto, K Sakai, ... Cell reports 34 (2), 2021 | 401 | 2021 |
| A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors RJ Park, T Wang, D Koundakjian, JF Hultquist, P Lamothe-Molina, ... Nature genetics 49 (2), 193-203, 2017 | 381 | 2017 |
| The restriction factors of human immunodeficiency virus RS Harris, JF Hultquist, DT Evans Journal of Biological Chemistry 287 (49), 40875-40883, 2012 | 355 | 2012 |
| A Cas9 ribonucleoprotein platform for functional genetic studies of HIV-host interactions in primary human T cells JF Hultquist, K Schumann, JM Woo, L Manganaro, MJ McGregor, ... Cell reports 17 (5), 1438-1452, 2016 | 211 | 2016 |
| Functional landscape of SARS-CoV-2 cellular restriction L Martin-Sancho, MK Lewinski, L Pache, CA Stoneham, X Yin, ME Becker, ... Molecular cell 81 (12), 2656-2668. e8, 2021 | 206 | 2021 |
| Protein interaction mapping identifies RBBP6 as a negative regulator of Ebola virus replication J Batra, JF Hultquist, D Liu, O Shtanko, J Von Dollen, L Satkamp, ... Cell 175 (7), 1917-1930. e13, 2018 | 147 | 2018 |
| Targeting viral proteostasis limits influenza virus, HIV, and dengue virus infection NS Heaton, N Moshkina, R Fenouil, TJ Gardner, S Aguirre, PS Shah, ... Immunity 44 (1), 46-58, 2016 | 143 | 2016 |
| Large dataset enables prediction of repair after CRISPR–Cas9 editing in primary T cells RT Leenay, A Aghazadeh, J Hiatt, D Tse, TL Roth, R Apathy, E Shifrut, ... Nature biotechnology 37 (9), 1034-1037, 2019 | 127 | 2019 |
| CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions JF Hultquist, J Hiatt, K Schumann, MJ McGregor, TL Roth, P Haas, ... Nature protocols 14 (1), 1-27, 2019 | 122 | 2019 |
| Endogenous origins of HIV-1 G-to-A hypermutation and restriction in the nonpermissive T cell line CEM2n EW Refsland, JF Hultquist, RS Harris PLoS pathogens 8 (7), e1002800, 2012 | 121 | 2012 |
| APOBEC3B and AID have similar nuclear import mechanisms L Lackey, ZL Demorest, AM Land, JF Hultquist, WL Brown, RS Harris Journal of molecular biology 419 (5), 301-314, 2012 | 118 | 2012 |
| Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity EW Refsland, JF Hultquist, EM Luengas, T Ikeda, NM Shaban, EK Law, ... PLoS genetics 10 (11), e1004761, 2014 | 114 | 2014 |
| A systems approach to infectious disease M Eckhardt, JF Hultquist, RM Kaake, R Hüttenhain, NJ Krogan Nature Reviews Genetics 21 (6), 339-354, 2020 | 113 | 2020 |
| Feminized tassels of maize mop1 and ts1 mutants exhibit altered levels of miR156 and specific SBP-box genes JF Hultquist, JE Dorweiler Planta 229 (1), 99-113, 2008 | 108 | 2008 |
| Cyclophilin A prevents HIV-1 restriction in lymphocytes by blocking human TRIM5α binding to the viral core A Selyutina, M Persaud, LM Simons, A Bulnes-Ramos, C Buffone, ... Cell reports 30 (11), 3766-3777. e6, 2020 | 103 | 2020 |
| Vif proteins of human and simian immunodeficiency viruses require cellular CBFβ to degrade APOBEC3 restriction factors JF Hultquist, M Binka, RS LaRue, V Simon, RS Harris Journal of virology 86 (5), 2874-2877, 2012 | 81 | 2012 |
| Longitudinal analysis of SARS-CoV-2 vaccine breakthrough infections reveals limited infectious virus shedding and restricted tissue distribution R Ke, PP Martinez, RL Smith, LL Gibson, CJ Achenbach, S McFall, C Qi, ... Open Forum Infectious Diseases 9 (7), ofac192, 2022 | 78 | 2022 |
