Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts L Zhuang, J Kim, RM Adam, KR Solomon, MR Freeman The Journal of clinical investigation 115 (4), 959-968, 2005 | 682 | 2005 |
Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease D Di Vizio, J Kim, MH Hager, M Morello, W Yang, CJ Lafargue, LD True, ... Cancer research 69 (13), 5601-5609, 2009 | 468 | 2009 |
Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease D Di Vizio, M Morello, AC Dudley, PW Schow, RM Adam, S Morley, ... The American journal of pathology 181 (5), 1573-1584, 2012 | 456 | 2012 |
Calcium-selective ion channel, CaT1, is apically localized in gastrointestinal tract epithelia and is aberrantly expressed in human malignancies L Zhuang, JB Peng, L Tou, H Takanaga, RM Adam, MA Hediger, ... Laboratory investigation 82 (12), 1755-1764, 2002 | 320 | 2002 |
Plasma levels of vascular endothelial growth factor are increased in patients with metastatic prostate cancer JLF Duque, KR Loughlin, RM Adam, PW Kantoff, D Zurakowski, ... Urology 54 (3), 523-527, 1999 | 315 | 1999 |
The phosphatidylinositol 3′-kinase pathway is a dominant growth factor-activated cell survival pathway in LNCaP human prostate carcinoma cells J Lin, RM Adam, E Santiestevan, MR Freeman Cancer research 59 (12), 2891-2897, 1999 | 311 | 1999 |
Calcium regulates the PI3K-Akt pathway in stretched osteoblasts TE Danciu, RM Adam, K Naruse, MR Freeman, PV Hauschka FEBS letters 536 (1-3), 193-197, 2003 | 235 | 2003 |
CaT1 expression correlates with tumor grade in prostate cancer JB Peng, L Zhuang, UV Berger, RM Adam, BJ Williams, EM Brown, ... Biochemical and Biophysical Research Communications 282 (3), 729-734, 2001 | 231 | 2001 |
Heparin-binding EGF-like growth factor is an autocrine growth factor for human urothelial cells and is synthesized by epithelial and smooth muscle cells in the human bladder. MR Freeman, JJ Yoo, G Raab, S Soker, RM Adam, FX Schneck, ... The Journal of clinical investigation 99 (5), 1028-1036, 1997 | 191 | 1997 |
Retinoid signaling in progenitors controls specification and regeneration of the urothelium D Gandhi, A Molotkov, E Batourina, K Schneider, H Dan, M Reiley, ... Developmental cell 26 (5), 469-482, 2013 | 165 | 2013 |
MYC mediates large oncosome-induced fibroblast reprogramming in prostate cancer VR Minciacchi, C Spinelli, M Reis-Sobreiro, L Cavallini, S You, M Zandian, ... Cancer research 77 (9), 2306-2317, 2017 | 164 | 2017 |
A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis C Guo, Y Sun, B Zhou, RM Adam, XK Li, WT Pu, BE Morrow, A Moon, X Li The Journal of clinical investigation 121 (4), 1585-1595, 2011 | 162 | 2011 |
Cholesterol sensitivity of endogenous and myristoylated Akt RM Adam, NK Mukhopadhyay, J Kim, D Di Vizio, B Cinar, K Boucher, ... Cancer research 67 (13), 6238-6246, 2007 | 159 | 2007 |
The pro‐apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1 B Cinar, PK Fang, M Lutchman, D Di Vizio, RM Adam, N Pavlova, ... The EMBO journal 26 (21), 4523-4534, 2007 | 155 | 2007 |
Fluidization and resolidification of the human bladder smooth muscle cell in response to transient stretch C Chen, R Krishnan, E Zhou, A Ramachandran, D Tambe, K Rajendran, ... PloS one 5 (8), e12035, 2010 | 143 | 2010 |
Evaluation of gel spun silk-based biomaterials in a murine model of bladder augmentation JR Mauney, GM Cannon, ML Lovett, EM Gong, D Di Vizio, P Gomez III, ... Biomaterials 32 (3), 808-818, 2011 | 142 | 2011 |
Extracellular calcium influx stimulates metalloproteinase cleavage and secretion of heparin‐binding EGF‐like growth factor independently of protein kinase C SM Dethlefsen, G Raab, MA Moses, RM Adam, M Klagsbrun, ... Journal of cellular biochemistry 69 (2), 143-153, 1998 | 140 | 1998 |
Loss of caveolin‐1 in prostate cancer stroma correlates with reduced relapse‐free survival and is functionally relevant to tumour progression G Ayala, M Morello, A Frolov, S You, R Li, F Rosati, G Bartolucci, G Danza, ... The Journal of pathology 231 (1), 77-87, 2013 | 137 | 2013 |
Induction of smooth muscle cell-like phenotype in marrow-derived cells among regenerating urinary bladder smooth muscle cells A Kanematsu, S Yamamoto, E Iwai-Kanai, I Kanatani, M Imamura, ... The American journal of pathology 166 (2), 565-573, 2005 | 123 | 2005 |
AP-1 mediates stretch-induced expression of HB-EGF in bladder smooth muscle cells JM Park, RM Adam, CA Peters, PD Guthrie, Z Sun, M Klagsbrun, ... American Journal of Physiology-Cell Physiology 277 (2), C294-C301, 1999 | 122 | 1999 |