Control of autoimmune diabetes in NOD mice by GAD expression or suppression in β cells JW Yoon, CS Yoon, HW Lim, QQ Huang, Y Kang, KH Pyun, K Hirasawa, ... Science 284 (5417), 1183-1187, 1999 | 368 | 1999 |
Reovirus oncolysis: the Ras/RalGEF/p38 pathway dictates host cell permissiveness to reovirus infection KL Norman, K Hirasawa, AD Yang, MA Shields, PWK Lee Proceedings of the National Academy of Sciences 101 (30), 11099-11104, 2004 | 250 | 2004 |
Oncolytic reovirus against ovarian and colon cancer K Hirasawa, SG Nishikawa, KL Norman, T Alain, A Kossakowska, ... Cancer research 62 (6), 1696-1701, 2002 | 235 | 2002 |
Reovirus oncolysis of human breast cancer KL Norman, MC Coffey, K Hirasawa, DJ Demetrick, SG Nishikawa, ... Human gene therapy 13 (5), 641-652, 2002 | 206 | 2002 |
Systemic reovirus therapy of metastatic cancer in immune-competent mice K Hirasawa, SG Nishikawa, KL Norman, MC Coffey, BG Thompson, ... Cancer research 63 (2), 348-353, 2003 | 201 | 2003 |
Reovirus therapy of lymphoid malignancies T Alain, K Hirasawa, KJ Pon, SG Nishikawa, SJ Urbanski, Y Auer, J Luider, ... Blood, The Journal of the American Society of Hematology 100 (12), 4146-4153, 2002 | 148 | 2002 |
Oncolytic viral therapy for prostate cancer: efficacy of reovirus as a biological therapeutic CM Thirukkumaran, MJ Nodwell, K Hirasawa, ZQ Shi, R Diaz, J Luider, ... Cancer research 70 (6), 2435-2444, 2010 | 121 | 2010 |
Negative regulation of the alpha interferon-induced antiviral response by the Ras/Raf/MEK pathway SM Battcock, TW Collier, D Zu, K Hirasawa Journal of virology 80 (9), 4422-4430, 2006 | 113 | 2006 |
Hepatitis C virus infection of cultured human hepatoma cells causes apoptosis and pyroptosis in both infected and bystander cells HM Kofahi, NGA Taylor, K Hirasawa, MD Grant, RS Russell Scientific reports 6 (1), 37433, 2016 | 108 | 2016 |
Effect of p38 mitogen-activated protein kinase on the replication of encephalomyocarditis virus K Hirasawa, A Kim, HS Han, J Han, HS Jun, JW Yoon Journal of virology 77 (10), 5649-5656, 2003 | 100 | 2003 |
Role of macrophages and macrophage-derived cytokines in the pathogenesis of Kilham rat virus-induced autoimmune diabetes in diabetes-resistant BioBreeding rats. YH Chung, HS Jun, Y Kang, K Hirasawa, BR Lee, N Van Rooijen, ... Journal of immunology (Baltimore, Md.: 1950) 159 (1), 466-471, 1997 | 97 | 1997 |
Antisense suppression of pygopus2 results in growth arrest of epithelial ovarian cancer CM Popadiuk, J Xiong, MG Wells, PG Andrews, K Dankwa, K Hirasawa, ... Clinical Cancer Research 12 (7), 2216-2223, 2006 | 95 | 2006 |
Possible role of macrophage-derived soluble mediators in the pathogenesis of encephalomyocarditis virus-induced diabetes in mice K Hirasawa, HS Jun, K Maeda, Y Kawaguchi, S Itagaki, T Mikami, ... Journal of virology 71 (5), 4024-4031, 1997 | 77 | 1997 |
In vitro and in vivo comparison of viral and cellular internal ribosome entry sites for bicistronic vector expression M Licursi, SL Christian, T Pongnopparat, K Hirasawa Gene therapy 18 (6), 631-636, 2011 | 74 | 2011 |
Activation of ERα signaling differentially modulates IFN-γ induced HLA-class II expression in breast cancer cells AA Mostafa, D Codner, K Hirasawa, Y Komatsu, MN Young, V Steimle, ... PLoS one 9 (1), e87377, 2014 | 72 | 2014 |
Analysis of PrPc mRNA by in situ Hybridization in Brain, Placenta, Uterus and Testis of Rats K Tanji, K Saekia, Y Matsumoto, M Takeda, K Hirasawa, K Doi, ... Intervirology 38 (6), 309-315, 1995 | 63 | 1995 |
Enhancement of cancer-specific protoporphyrin IX fluorescence by targeting oncogenic Ras/MEK pathway E Yoshioka, VS Chelakkot, M Licursi, SG Rutihinda, J Som, L Derwish, ... Theranostics 8 (8), 2134, 2018 | 61 | 2018 |
Mcl-1 and Bcl-xL are essential for survival of the developing nervous system LC Fogarty, RT Flemmer, BA Geizer, M Licursi, A Karunanithy, ... Cell Death & Differentiation 26 (8), 1501-1515, 2019 | 58 | 2019 |
Prevention of encephalomyocarditis virus-induced diabetes in mice by inhibition of the tyrosine kinase signalling pathway and subsequent suppression of nitric oxide production … K Hirasawa, HS Jun, HS Han, ML Zhang, MD Hollenberg, JW Yoon Journal of virology 73 (10), 8541-8548, 1999 | 56 | 1999 |
Molecular cloning and characterization of a new member of the rat placental prolactin (PRL) family, PRL-like protein D (PLP-D) K Iwatsuki, M Shinozaki, N Hattori, K Hirasawa, S Itagaki, K Shiota, ... Endocrinology 137 (9), 3849-3855, 1996 | 54 | 1996 |