| Sulforhodamine B (SRB) assay in cell culture to investigate cell proliferation EA Orellana, AL Kasinski Bio-protocol 6 (21), e1984-e1984, 2016 | 464 | 2016 |
| A combinatorial microRNA therapeutics approach to suppressing non-small cell lung cancer AL Kasinski, K Kelnar, C Stahlhut, E Orellana, J Zhao, E Shimer, S Dysart, ... Oncogene 34 (27), 3547-3555, 2015 | 239 | 2015 |
| METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation EA Orellana, Q Liu, E Yankova, M Pirouz, E De Braekeleer, W Zhang, ... Molecular cell 81 (16), 3323-3338. e14, 2021 | 233 | 2021 |
| MicroRNAs in cancer: a historical perspective on the path from discovery to therapy EA Orellana, AL Kasinski Cancers 7 (3), 1388-1405, 2015 | 148 | 2015 |
| METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing H Chen, L Gu, EA Orellana, Y Wang, J Guo, QI Liu, L Wang, Z Shen, H Wu, ... Cell research 30 (6), 544-547, 2020 | 124 | 2020 |
| Synthetic lethality of Wnt pathway activation and asparaginase in drug-resistant acute leukemias L Hinze, M Pfirrmann, S Karim, J Degar, C McGuckin, D Vinjamur, ... Cancer cell 35 (4), 664-676. e7, 2019 | 105 | 2019 |
| tRNA dysregulation and disease EA Orellana, E Siegal, RI Gregory Nature Reviews Genetics 23 (11), 651-664, 2022 | 94 | 2022 |
| FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer EA Orellana, S Tenneti, L Rangasamy, LT Lyle, PS Low, AL Kasinski Science translational medicine 9 (401), eaam9327, 2017 | 87 | 2017 |
| Structural basis of regulated m7G tRNA modification by METTL1–WDR4 J Li, L Wang, Q Hahn, RP Nowak, T Viennet, EA Orellana, ... Nature 613 (7943), 391-397, 2023 | 61 | 2023 |
| Biosynthesis and genomic analysis of medium-chain hydrocarbon production by the endophytic fungal isolate Nigrograna mackinnonii E5202H JJ Shaw, DJ Spakowicz, RS Dalal, JH Davis, NA Lehr, BF Dunican, ... Applied Microbiology and Biotechnology 99, 3715-3728, 2015 | 61 | 2015 |
| Enhancing microRNA activity through increased endosomal release mediated by nigericin EA Orellana, AM Abdelaal, L Rangasamy, S Tenneti, S Myoung, PS Low, ... Molecular Therapy Nucleic Acids 16, 505-518, 2019 | 33 | 2019 |
| New Mechanism for Release of Endosomal Contents: Osmotic Lysis via Nigericin-Mediated K+/H+ Exchange L Rangasamy, V Chelvam, AK Kanduluru, M Srinivasarao, NA Bandara, ... Bioconjugate chemistry 29 (4), 1047-1059, 2018 | 30 | 2018 |
| In tobacco BY-2 cells xyloglucan oligosaccharides alter the expression of genes involved in cell wall metabolism, signalling, stress responses, cell division and … L González-Pérez, L Perrotta, A Acosta, E Orellana, N Spadafora, L Bruno, ... Molecular Biology Reports 41, 6803-6816, 2014 | 29 | 2014 |
| Identification and validation of microRNAs that synergize with miR-34a–a basis for combinatorial microRNA therapeutics EA Orellana, C Li, A Lisevick, AL Kasinski Cell Cycle 18 (15), 1798-1811, 2019 | 24 | 2019 |
| Sulforhodamine B (SRB) assay in cell culture to investigate cell proliferation. Bio Protoc. 2016 EA Orellana, AL Kasinski | 15 | 1984 |
| Selective targeting of chemically modified miR-34a to prostate cancer using a small molecule ligand and an endosomal escape agent AM Abdelaal, IS Sohal, SG Iyer, K Sudarshan, EA Orellana, KE Ozcan, ... Molecular Therapy-Nucleic Acids 35 (2), 2024 | 8 | 2024 |
| No vehicle, no problem EA Orellana, AL Kasinski Oncotarget 8 (57), 96470, 2017 | 5 | 2017 |
| A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation RH Ali, EA Orellana, SH Lee, YC Chae, Y Chen, J Clauwaert, ... Molecular Cell, 2025 | | 2025 |
| A noncatalytic role for mettl1 in oncogenic translation in soft tissue sarcoma RH Ali, B Silverman, EA Orellana, A Kennedy, C Bowers, A Gutierrez, ... Cancer Research 83 (7_Supplement), 3500-3500, 2023 | | 2023 |
| S859 GENOME‐WIDE CRISPR‐CAS9 SCREEN REVEALS SYNTHETIC LETHALITY OF WNT PATHWAY ACTIVATION AND ASPARAGINASE IN DRUG‐RESISTANT ACUTE LEUKEMIAS L Hinze, M Pfirrmann, S Karim, J Degar, C McGuckin, D Vinjamur, ... HemaSphere 3, 384, 2019 | | 2019 |
