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Jorge Gómez Tejeda Zañudo
Jorge Gómez Tejeda Zañudo
Senior Scientist (Dana-Farber Cancer Institute, Broad Institute)
Bestätigte E-Mail-Adresse bei broadinstitute.org - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Structure-based control of complex networks with nonlinear dynamics
JGT Zañudo, G Yang, R Albert
Proceedings of the National Academy of Sciences 114 (28), 7234-7239, 2017
2632017
Network modeling of TGFβ signaling in hepatocellular carcinoma epithelial-to-mesenchymal transition reveals joint sonic hedgehog and Wnt pathway activation
SN Steinway, JGT Zañudo, W Ding, CB Rountree, DJ Feith, ...
Cancer research 74 (21), 5963-5977, 2014
2502014
Cell fate reprogramming by control of intracellular network dynamics
JGT Zañudo, R Albert
PLOS Computational Biology 11 (4), e1004193, 2015
2252015
The Angiosarcoma Project: enabling genomic and clinical discoveries in a rare cancer through patient-partnered research
CA Painter, E Jain, BN Tomson, M Dunphy, RE Stoddard, BS Thomas, ...
Nature medicine 26 (2), 181-187, 2020
2242020
An effective network reduction approach to find the dynamical repertoire of discrete dynamic networks
JGT Zañudo, R Albert
Chaos: An Interdisciplinary Journal of Nonlinear Science 23 (2), 2013
1522013
Combinatorial interventions inhibit TGFβ-driven epithelial-to-mesenchymal transition and support hybrid cellular phenotypes
SN Steinway, JGT Zañudo, PJ Michel, DJ Feith, TP Loughran, R Albert
NPJ systems biology and applications 1 (1), 1-12, 2015
1352015
Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer: final 10-year analysis of the open-label, single-arm, phase 2 APT trial
SM Tolaney, P Tarantino, N Graham, N Tayob, L Parè, G Villacampa, ...
The Lancet Oncology 24 (3), 273-285, 2023
1042023
A new discrete dynamic model of ABA-induced stomatal closure predicts key feedback loops
R Albert, BR Acharya, BW Jeon, JGT Zañudo, M Zhu, K Osman, ...
PLoS biology 15 (9), e2003451, 2017
642017
Discrete dynamic network modeling of oncogenic signaling: Mechanistic insights for personalized treatment of cancer
JGT Zañudo, SN Steinway, R Albert
Current Opinion in Systems Biology 9, 1-10, 2018
612018
A network modeling approach to elucidate drug resistance mechanisms and predict combinatorial drug treatments in breast cancer
J Gómez Tejeda Zañudo, M Scaltriti, R Albert
Cancer convergence 1, 1-25, 2017
612017
Parity and time reversal elucidate both decision-making in empirical models and attractor scaling in critical Boolean networks
JC Rozum, J Gómez Tejeda Zañudo, X Gan, D Deritei, R Albert
Science Advances 7 (29), eabf8124, 2021
552021
Target control in logical models using the domain of influence of nodes
G Yang, J Gómez Tejeda Zañudo, R Albert
Frontiers in physiology 9, 454, 2018
532018
Towards control of cellular decision-making networks in the epithelial-to-mesenchymal transition
JGT Zañudo, MT Guinn, K Farquhar, M Szenk, SN Steinway, G Balázsi, ...
Physical biology 16 (3), 031002, 2019
512019
Boolean threshold networks: Virtues and limitations for biological modeling
JGT Zanudo, M Aldana, G Martínez-Mekler
Information Processing and Biological Systems, 113-151, 2011
492011
pystablemotifs: Python library for attractor identification and control in Boolean networks
JC Rozum, D Deritei, KH Park, J Gómez Tejeda Zañudo, R Albert
Bioinformatics 38 (5), 1465-1466, 2022
392022
ER+ breast cancer strongly depends on MCL-1 and BCL-xL anti-apoptotic proteins
C Alcon, JGT Zañudo, R Albert, N Wagle, M Scaltriti, A Letai, J Samitier, ...
Cells 10 (7), 1659, 2021
232021
Mathematical modeling of the Candida albicans yeast to hyphal transition reveals novel control strategies
DJ Wooten, JGT Zañudo, D Murrugarra, AM Perry, A Dongari-Bagtzoglou, ...
PLoS computational biology 17 (3), e1008690, 2021
212021
Cell Line–Specific Network Models of ER+ Breast Cancer Identify Potential PI3Kα Inhibitor Resistance Mechanisms and Drug Combinations
J Gómez Tejeda Zañudo, P Mao, C Alcon, K Kowalski, GN Johnson, G Xu, ...
Cancer research 81 (17), 4603-4617, 2021
192021
Structure-based approach to identifying small sets of driver nodes in biological networks
E Newby, JG Tejeda Zañudo, R Albert
Chaos: An Interdisciplinary Journal of Nonlinear Science 32 (6), 2022
152022
The Metastatic Breast Cancer Project: leveraging patient-partnered research to expand the clinical and genomic landscape of metastatic breast cancer and accelerate discoveries
E Jain, JGT Zañudo, M McGillicuddy, DL Abravanel, BS Thomas, D Kim, ...
medRxiv, 2023.06. 07.23291117, 2023
92023
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