| Viral evasion of intracellular DNA and RNA sensing YK Chan, MU Gack Nature Reviews Microbiology 14 (6), 360-373, 2016 | 489 | 2016 |
| TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine S Jemielity, JJ Wang, YK Chan, AA Ahmed, W Li, S Monahan, X Bu, ... PLoS pathogens 9 (3), e1003232, 2013 | 393 | 2013 |
| CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during West Nile virus encephalitis B Zhang, YK Chan, B Lu, MS Diamond, RS Klein The Journal of Immunology 180 (4), 2641-2649, 2008 | 197 | 2008 |
| RIG-I-like receptor regulation in virus infection and immunity YK Chan, MU Gack Current opinion in virology 12, 7-14, 2015 | 184 | 2015 |
| Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses YK Chan, SK Wang, CJ Chu, DA Copland, AJ Letizia, H Costa Verdera, ... Science translational medicine 13 (580), eabd3438, 2021 | 180 | 2021 |
| Ligation of Fc gamma receptor IIB inhibits antibody-dependent enhancement of dengue virus infection KR Chan, SLX Zhang, HC Tan, YK Chan, A Chow, APC Lim, ... Proceedings of the National Academy of Sciences 108 (30), 12479-12484, 2011 | 170 | 2011 |
| The ubiquitin-specific protease USP15 promotes RIG-I–mediated antiviral signaling by deubiquitylating TRIM25 EK Pauli, YK Chan, ME Davis, S Gableske, MK Wang, KF Feister, ... Science signaling 7 (307), ra3-ra3, 2014 | 168 | 2014 |
| Zika virus NS3 mimics a cellular 14-3-3-binding motif to antagonize RIG-I-and MDA5-mediated innate immunity W Riedl, D Acharya, JH Lee, G Liu, T Serman, C Chiang, YK Chan, ... Cell host & microbe 26 (4), 493-503. e6, 2019 | 133 | 2019 |
| A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity YK Chan, MU Gack Nature immunology 17 (5), 523-530, 2016 | 125 | 2016 |
| Adeno-associated virus (AAV) versus immune response J Rabinowitz, YK Chan, RJ Samulski Viruses 11 (2), 102, 2019 | 118 | 2019 |
| Management of neuroinflammatory responses to AAV-mediated gene therapies for neurodegenerative diseases BA Perez, A Shutterly, YK Chan, BJ Byrne, M Corti Brain sciences 10 (2), 119, 2020 | 110 | 2020 |
| IFITM proteins restrict antibody-dependent enhancement of dengue virus infection YK Chan, IC Huang, M Farzan PloS one 7 (3), e34508, 2012 | 66 | 2012 |
| Circumventing cellular immunity by miR142-mediated regulation sufficiently supports rAAV-delivered OVA expression without activating humoral immunity Y Xiao, M Muhuri, S Li, W Qin, G Xu, L Luo, J Li, AJ Letizia, SK Wang, ... JCI insight 4 (13), e99052, 2019 | 43 | 2019 |
| Inflammation in viral vector-mediated ocular gene therapy: a review and report from a workshop hosted by the foundation fighting blindness, 9/2020 YK Chan, AD Dick, SM Hall, T Langmann, CL Scribner, BC Mansfield, ... Translational vision science & technology 10 (4), 3-3, 2021 | 37 | 2021 |
| The herpesvirus accessory protein γ134.5 facilitates viral replication by disabling mitochondrial translocation of RIG-I X Liu, Y Ma, K Voss, M van Gent, YK Chan, MU Gack, M Gale Jr, B He PLoS pathogens 17 (3), e1009446, 2021 | 22 | 2021 |
| Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder ET Lim, Y Chan, P Dawes, X Guo, S Erdin, DJC Tai, S Liu, JM Reichert, ... Nature Communications 13 (1), 3243, 2022 | 19 | 2022 |
| Enabling multiplexed testing of pooled donor cells through whole-genome sequencing Y Chan, YK Chan, DB Goodman, X Guo, A Chavez, ET Lim, GM Church Genome medicine 10, 1-11, 2018 | 11 | 2018 |
| Reducing AAV-mediated immune responses and pathology in a subretinal pig model by engineering the vector genome YK Chan, S Wang, A Letizia, Y Chan, E Lim, A Graveline, HC Verdera, ... Molecular Therapy 27 (4), 298-298, 2019 | 7 | 2019 |
| An unbiased index to quantify participant’s phenotypic contribution to an open-access cohort Y Chan, M Tung, AS Garruss, SW Zaranek, YK Chan, JE Lunshof, ... Scientific Reports 7 (1), 46148, 2017 | 7 | 2017 |
| RIG-I works double duty YK Chan, MU Gack Cell host & microbe 17 (3), 285-287, 2015 | 7 | 2015 |