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Tian-Min Fu
Tian-Min Fu
The Ohio State University
Bestätigte E-Mail-Adresse bei crystal.harvard.edu
Titel
Zitiert von
Zitiert von
Jahr
Gasdermin D pore structure reveals preferential release of mature interleukin-1
S Xia, Z Zhang, VG Magupalli, JL Pablo, Y Dong, SM Vora, L Wang, ...
Nature 593 (7860), 607-611, 2021
4552021
Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway
YR Lee, M Chen, JD Lee, J Zhang, SY Lin, TM Fu, H Chen, T Ishikawa, ...
Science 364 (6441), eaau0159, 2019
2662019
Structural basis and functional role of intramembrane trimerization of the Fas/CD95 death receptor
Q Fu, TM Fu, AC Cruz, P Sengupta, SK Thomas, S Wang, RM Siegel, ...
Molecular cell 61 (4), 602-613, 2016
2132016
Molecular mechanism of V (D) J recombination from synaptic RAG1-RAG2 complex structures
H Ru, MG Chambers, TM Fu, AB Tong, M Liao, H Wu
Cell 163 (5), 1138-1152, 2015
2002015
Cryo-EM structure of caspase-8 tandem DED filament reveals assembly and regulation mechanisms of the death-inducing signaling complex
TM Fu, Y Li, A Lu, Z Li, PR Vajjhala, AC Cruz, DB Srivastava, F DiMaio, ...
Molecular cell 64 (2), 236-250, 2016
1902016
Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism
A Lu, Y Li, FI Schmidt, Q Yin, S Chen, TM Fu, AB Tong, HL Ploegh, Y Mao, ...
Nature structural & molecular biology 23 (5), 416-425, 2016
1732016
Structures and gating mechanism of human TRPM2
L Wang, TM Fu, Y Zhou, S Xia, A Greka, H Wu
Science 362 (6421), eaav4809, 2018
1682018
Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome
C Shen, R Li, R Negro, J Cheng, SM Vora, TM Fu, A Wang, K He, ...
Cell 184 (23), 5759-5774. e20, 2021
1662021
Higher-order clustering of the transmembrane anchor of DR5 drives signaling
L Pan, TM Fu, W Zhao, L Zhao, W Chen, C Qiu, W Liu, Z Liu, A Piai, Q Fu, ...
Cell 176 (6), 1477-1489. e14, 2019
1462019
Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold
P Fontana, Y Dong, X Pi, AB Tong, CW Hecksel, L Wang, TM Fu, ...
Science 376 (6598), eabm9326, 2022
1402022
Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1
Y Li, TM Fu, A Lu, K Witt, J Ruan, C Shen, H Wu
Proceedings of the National Academy of Sciences 115 (43), 10845-10852, 2018
1322018
Structures of a complete human V-ATPase reveal mechanisms of its assembly
L Wang, D Wu, CV Robinson, H Wu, TM Fu
Molecular cell 80 (3), 501-511. e3, 2020
1302020
Structural biology of innate immunity
Q Yin, TM Fu, J Li, H Wu
Annual review of immunology 33 (1), 393-416, 2015
1292015
K63-linked polyubiquitin chains bind to DNA to facilitate DNA damage repair
† Pengda Liu1,2,*,†, Wenjian Gan1,*, Siyuan Su2,*, Arthur V. Hauenstein3 ...
science signaling 11 (533), 2018
1112018
Molecular mechanism for NLRP6 inflammasome assembly and activation
C Shen, A Lu, WJ Xie, J Ruan, R Negro, EH Egelman, TM Fu, H Wu
Proceedings of the National Academy of Sciences 116 (6), 2052-2057, 2019
1092019
Targeting stem-loop 1 of the SARS-CoV-2 5′ UTR to suppress viral translation and Nsp1 evasion
SM Vora, P Fontana, T Mao, V Leger, Y Zhang, TM Fu, J Lieberman, ...
Proceedings of the National Academy of Sciences 119 (9), e2117198119, 2022
942022
SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism
M Shi, L Wang, P Fontana, S Vora, Y Zhang, TM Fu, J Lieberman, H Wu
BioRxiv, 2020
742020
Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes
L Robert Hollingsworth, L David, Y Li, AR Griswold, J Ruan, H Sharif, ...
Nature communications 12 (1), 189, 2021
622021
Crystal structure of the F27G AIM2 PYD mutant and similarities of its self-association to DED/DED interactions
A Lu, V Kabaleeswaran, T Fu, VG Magupalli, H Wu
Journal of molecular biology 426 (7), 1420-1427, 2014
622014
Mechanism of ubiquitin transfer promoted by TRAF6
TM Fu, C Shen, Q Li, P Zhang, H Wu
Proceedings of the National Academy of Sciences 115 (8), 1783-1788, 2018
462018
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