High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ... Cell 163 (6), 1515-1526, 2015 | 1724 | 2015 |
A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice C Escribano-Díaz, A Orthwein, A Fradet-Turcotte, M Xing, JTF Young, ... Molecular cell 49 (5), 872-883, 2013 | 1079 | 2013 |
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark A Fradet-Turcotte, MD Canny, C Escribano-Díaz, A Orthwein, CCY Leung, ... Nature 499 (7456), 50-54, 2013 | 776 | 2013 |
RETRACTED: Mitosis Inhibits DNA Double-Strand Break Repair to Guard Against Telomere Fusions A Orthwein, A Fradet-Turcotte, SM Noordermeer, MD Canny, CM Brun, ... Science 344 (6180), 189-193, 2014 | 387 | 2014 |
The TIP60 complex regulates bivalent chromatin recognition by 53BP1 through direct H4K20me binding and H2AK15 acetylation K Jacquet, A Fradet-Turcotte, N Avvakumov, JP Lambert, C Roques, ... Molecular cell 62 (3), 409-421, 2016 | 284 | 2016 |
Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR–Cas9 genome-editing efficiency MD Canny, N Moatti, LCK Wan, A Fradet-Turcotte, D Krasner, ... Nature biotechnology 36 (1), 95-102, 2018 | 276 | 2018 |
The structural basis of modified nucleosome recognition by 53BP1 MD Wilson, S Benlekbir, A Fradet-Turcotte, A Sherker, JP Julien, ... Nature 536 (7614), 100-103, 2016 | 253 | 2016 |
Virus DNA replication and the host DNA damage response MD Weitzman, A Fradet-Turcotte Annual review of virology 5, 141-164, 2018 | 197 | 2018 |
Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks S Panier, Y Ichijima, A Fradet-Turcotte, CCY Leung, L Kaustov, ... Molecular cell 47 (3), 383-395, 2012 | 176 | 2012 |
Nuclear accumulation of the papillomavirus E1 helicase blocks S-phase progression and triggers an ATM-dependent DNA damage response A Fradet-Turcotte, F Bergeron-Labrecque, CA Moody, M Lehoux, ... Journal of virology 85 (17), 8996-9012, 2011 | 154 | 2011 |
Human papillomaviruses activate caspases upon epithelial differentiation to induce viral genome amplification CA Moody, A Fradet-Turcotte, J Archambault, LA Laimins Proceedings of the National Academy of Sciences 104 (49), 19541-19546, 2007 | 135 | 2007 |
BRCA2 functions: from DNA repair to replication fork stabilization A Fradet-Turcotte, J Sitz, D Grapton, A Orthwein Endocr Relat Cancer 23 (10), T1-T17, 2016 | 115 | 2016 |
RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks M Bohgaki, T Bohgaki, S El Ghamrasni, T Srikumar, G Maire, S Panier, ... Proceedings of the National Academy of Sciences 110 (52), 20982-20987, 2013 | 114 | 2013 |
Proteasomal degradation of the papillomavirus E2 protein is inhibited by overexpression of bromodomain-containing protein 4 D Gagnon, S Joubert, H Sénéchal, A Fradet-Turcotte, S Torre, ... Journal of virology 83 (9), 4127-4139, 2009 | 104 | 2009 |
ActiveDriverDB: human disease mutations and genome variation in post-translational modification sites of proteins M Krassowski, M Paczkowska, K Cullion, T Huang, I Dzneladze, ... Nucleic acids research 46 (D1), D901-D910, 2018 | 91 | 2018 |
Nuclear export of human papillomavirus type 31 E1 is regulated by Cdk2 phosphorylation and required for viral genome maintenance A Fradet-Turcotte, C Moody, LA Laimins, J Archambault Journal of virology 84 (22), 11747-11760, 2010 | 79 | 2010 |
Human papillomavirus E7 oncoprotein targets RNF168 to hijack the host DNA damage response J Sitz, SA Blanchet, SF Gameiro, E Biquand, TM Morgan, M Galloy, ... Proceedings of the National Academy of Sciences 116 (39), 19552-19562, 2019 | 68 | 2019 |
Development of quantitative and high-throughput assays of polyomavirus and papillomavirus DNA replication A Fradet-Turcotte, G Morin, M Lehoux, PA Bullock, J Archambault Virology 399 (1), 65-76, 2010 | 59 | 2010 |
p53 and TFIIEα share a common binding site on the Tfb1/p62 subunit of TFIIH P Di Lello, LM Miller Jenkins, C Mas, C Langlois, E Malitskaya, ... Proceedings of the National Academy of Sciences 105 (1), 106-111, 2008 | 55 | 2008 |
The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage J Kitevski-LeBlanc, A Fradet-Turcotte, P Kukic, MD Wilson, G Portella, ... Elife 6, e23872, 2017 | 54 | 2017 |