GPR109A is a G-protein–coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon M Thangaraju, GA Cresci, K Liu, S Ananth, JP Gnanaprakasam, ... Cancer research 69 (7), 2826-2832, 2009 | 808 | 2009 |
Common activation mechanism of class A GPCRs Q Zhou, D Yang, M Wu, Y Guo, W Guo, L Zhong, X Cai, A Dai, W Jang, ... Elife 8, e50279, 2019 | 528 | 2019 |
Mini G protein probes for active G protein–coupled receptors (GPCRs) in live cells Q Wan, N Okashah, A Inoue, R Nehmé, B Carpenter, CG Tate, ... Journal of Biological Chemistry 293 (19), 7466-7473, 2018 | 346 | 2018 |
Differentiation of human embryonic stem cells to dopaminergic neurons in serum‐free suspension culture TC Schulz, SA Noggle, GM Palmarini, DA Weiler, IG Lyons, KA Pensa, ... Stem cells 22 (7), 1218-1238, 2004 | 320 | 2004 |
Blockade of dendritic cell development by bacterial fermentation products butyrate and propionate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases N Singh, M Thangaraju, PD Prasad, PM Martin, NA Lambert, T Boettger, ... Journal of Biological Chemistry 285 (36), 27601-27608, 2010 | 308 | 2010 |
Targeted inactivation of the sodium‐calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization SV Koushik, J Wang, R Rogers, D Moskophidis, NA Lambert, TL Creazzo, ... The FASEB Journal 15 (7), 1209-1211, 2001 | 295 | 2001 |
Inactive-state preassembly of Gq-coupled receptors and Gq heterotrimers K Qin, C Dong, G Wu, NA Lambert Nature chemical biology 7 (10), 740-747, 2011 | 227 | 2011 |
Some G protein heterotrimers physically dissociate in living cells GJ Digby, RM Lober, PR Sethi, NA Lambert Proceedings of the National Academy of Sciences 103 (47), 17789-17794, 2006 | 198 | 2006 |
The c-terminus of GRK3 indicates rapid dissociation of G protein heterotrimers B Hollins, S Kuravi, GJ Digby, NA Lambert Cellular signalling 21 (6), 1015-1021, 2009 | 167 | 2009 |
Variable G protein determinants of GPCR coupling selectivity N Okashah, Q Wan, S Ghosh, M Sandhu, A Inoue, N Vaidehi, NA Lambert Proceedings of the National Academy of Sciences 116 (24), 12054-12059, 2019 | 163 | 2019 |
Induction and reversal of long-term potentiation by low-and high-intensity theta pattern stimulation DS Barr, NA Lambert, KL Hoyt, SD Moore, WA Wilson Journal of Neuroscience 15 (7), 5402-5410, 1995 | 159 | 1995 |
Three-dimensional neural constructs: a novel platform for neurophysiological investigation HR Irons, DK Cullen, NP Shapiro, NA Lambert, RH Lee, MC LaPlaca Journal of neural engineering 5 (3), 333, 2008 | 146 | 2008 |
Adenosine depresses excitatory but not fast inhibitory synaptic transmission in area CA1 of the rat hippocampus NA Lambert, TJ Teyler Neuroscience letters 122 (1), 50-52, 1991 | 141 | 1991 |
Role of HCO3-ions in depolarizing GABAA receptor-mediated responses in pyramidal cells of rat hippocampus LM Grover, NA Lambert, PA Schwartzkroin, TJ Teyler Journal of Neurophysiology 69 (5), 1541-1555, 1993 | 135 | 1993 |
CODA-RET reveals functional selectivity as a result of GPCR heteromerization E Urizar, H Yano, R Kolster, C Galés, N Lambert, JA Javitch Nature chemical biology 7 (9), 624-630, 2011 | 128 | 2011 |
Dissociation of heterotrimeric g proteins in cells NA Lambert Science signaling 1 (25), re5-re5, 2008 | 123 | 2008 |
Minireview: GPCR and G proteins: Drug efficacy and activation in live cells JP Vilardaga, M Bünemann, TN Feinstein, N Lambert, VO Nikolaev, ... Molecular endocrinology 23 (5), 590-599, 2009 | 115 | 2009 |
Regulators of G-protein signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity NA Lambert, CA Johnston, SD Cappell, S Kuravi, AJ Kimple, FS Willard, ... Proceedings of the National Academy of Sciences 107 (15), 7066-7071, 2010 | 108 | 2010 |
Instability of a class AG protein-coupled receptor oligomer interface JM Fonseca, NA Lambert Molecular pharmacology 75 (6), 1296-1299, 2009 | 108 | 2009 |
Hyperpolarizing and depolarizing GABAA receptor-mediated dendritic inhibition in area CA1 of the rat hippocampus NA Lambert, AM Borroni, LM Grover, TJ Teyler Journal of neurophysiology 66 (5), 1538-1548, 1991 | 108 | 1991 |