Bacterial multidrug efflux pumps: much more than antibiotic resistance determinants P Blanco, S Hernando-Amado, JA Reales-Calderon, F Corona, F Lira, ... Microorganisms 4 (1), 14, 2016 | 761 | 2016 |
Multidrug efflux pumps at the crossroad between antibiotic resistance and bacterial virulence M Alcalde-Rico, S Hernando-Amado, P Blanco, JL Martínez Frontiers in microbiology 7, 1483, 2016 | 252 | 2016 |
Multidrug efflux pumps as main players in intrinsic and acquired resistance to antimicrobials S Hernando-Amado, P Blanco, M Alcalde-Rico, F Corona, ... Drug Resistance Updates 28, 13-27, 2016 | 216 | 2016 |
Metabolic Compensation of Fitness Costs Is a General Outcome for Antibiotic-Resistant Pseudomonas aeruginosa Mutants Overexpressing Efflux Pumps J Olivares Pacheco, C Alvarez-Ortega, M Alcalde Rico, JL Martínez MBio 8 (4), 10.1128/mbio. 00500-17, 2017 | 94 | 2017 |
Role of the Multidrug Resistance Efflux Pump MexCD-OprJ in the Pseudomonas aeruginosa Quorum Sensing Response M Alcalde-Rico, J Olivares-Pacheco, C Alvarez-Ortega, M Cámara, ... Frontiers in Microbiology 9, 2752, 2018 | 85 | 2018 |
Naringenin inhibition of the Pseudomonas aeruginosa quorum sensing response is based on its time-dependent competition with N-(3-Oxo-dodecanoyl)-L-homoserine lactone for LasR … S Hernando-Amado, M Alcalde-Rico, T Gil-Gil, JR Valverde, JL Martínez Frontiers in molecular biosciences 7, 25, 2020 | 64 | 2020 |
The development of efflux pump inhibitors to treat Gram-negative infections P Blanco, F Sanz-García, S Hernando-Amado, JL Martínez, ... Expert opinion on drug discovery 13 (10), 919-931, 2018 | 49 | 2018 |
The impaired quorum sensing response of Pseudomonas aeruginosa MexAB‐OprM efflux pump overexpressing mutants is not due to non‐physiological efflux of 3 … M Alcalde‐Rico, J Olivares‐Pacheco, N Halliday, M Cámara, JL Martínez Environmental microbiology 22 (12), 5167-5188, 2020 | 37 | 2020 |
Novel Inducers of the Expression of Multidrug Efflux Pumps That Trigger Pseudomonas aeruginosa Transient Antibiotic Resistance P Laborda, M Alcalde-Rico, P Blanco, JL Martínez, S Hernando-Amado Antimicrobial Agents and Chemotherapy 63 (11), 10.1128/aac. 01095-19, 2019 | 31 | 2019 |
Discovery of inhibitors of Pseudomonas aeruginosa virulence through the search for natural‐like compounds with a dual role as inducers and substrates of efflux … P Laborda, M Alcalde‐Rico, A Chini, JL Martínez, S Hernando‐Amado Environmental Microbiology 23 (12), 7396-7411, 2021 | 23 | 2021 |
The analysis of the antibiotic resistome offers new opportunities for therapeutic intervention F Corona, P Blanco, M Alcalde-Rico, S Hernando-Amado, F Lira, ... Future medicinal chemistry 8 (10), 1133-1151, 2016 | 21 | 2016 |
Mutations in the efflux pump regulator MexZ shift tissue colonization by Pseudomonas aeruginosa to a state of antibiotic tolerance P Laborda, S Lolle, S Hernando-Amado, M Alcalde-Rico, K Aanæs, ... Nature Communications 15 (1), 2584, 2024 | 11 | 2024 |
The MexJK Multidrug Efflux Pump Is Not Involved in Acquired or Intrinsic Antibiotic Resistance in Pseudomonas aeruginosa, but Modulates the Bacterial Quorum … R Amieva, T Gil-Gil, JL Martínez, M Alcalde-Rico International Journal of Molecular Sciences 23 (14), 7492, 2022 | 10 | 2022 |
Genetic characterization of clinically relevant class 1 integrons carried by multidrug resistant bacteria (MDRB) isolated from the gut microbiota of highly antibiotic treated … F Vásquez-Ponce, S Higuera-Llantén, J Parás-Silva, N Gamboa-Acuña, ... Journal of Global Antimicrobial Resistance 29, 55-62, 2022 | 10 | 2022 |
Acquisition of resistance to ceftazidime-avibactam during infection treatment in Pseudomonas aeruginosa through D179Y mutation in one of two blaKPC-2 gene … P García, B Brito, M Alcalde-Rico, JM Munita, JRW Martínez, ... Frontiers in Cellular and Infection Microbiology 12, 981792, 2022 | 8 | 2022 |
Methods for measuring the production of quorum sensing signal molecules M Alcalde-Rico, JL Martínez Antibiotic Resistance Protocols, 1-15, 2018 | 6 | 2018 |
Dynamics of the MRSA population in a Chilean hospital: a phylogenomic analysis (2000–2016) JRW Martínez, PJ Planet, M Spencer-Sandino, L Rivas, L Díaz, ... Microbiology Spectrum 11 (4), e05351-22, 2023 | 5 | 2023 |
Isolation of an Extensively Drug-Resistant Pseudomonas aeruginosa exoS+/O4 Strain Belonging to the “High-Risk” Clone ST654 and Coproducer of NDM-1 and … A Opazo-Capurro, F Morales-León, C Jerez, J Olivares-Pacheco, ... Microbiology Spectrum 10 (5), e01439-22, 2022 | 5 | 2022 |
Use of phenotype microarrays to study the effect of acquisition of resistance to antimicrobials in bacterial physiology JA Reales-Calderon, P Blanco, M Alcalde-Rico, F Corona, F Lira, ... Research in microbiology 167 (9-10), 723-730, 2016 | 5 | 2016 |
Activity of imipenem/relebactam and comparators against KPC-producing Klebsiella pneumoniae and imipenem-resistant Pseudomonas aeruginosa M Delgado-Valverde, I Portillo-Calderón, M Alcalde-Rico, MC Conejo, ... European Journal of Clinical Microbiology & Infectious Diseases 43 (3), 445-457, 2024 | 4 | 2024 |