| A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts R Li, J Liang, S Ni, T Zhou, X Qing, H Li, W He, J Chen, F Li, Q Zhuang, ... Cell stem cell 7 (1), 51-63, 2010 | 1369 | 2010 |
| RS-1 enhances CRISPR/Cas9-and TALEN-mediated knock-in efficiency J Song, D Yang, J Xu, T Zhu, YE Chen, J Zhang Nature communications 7 (1), 1-7, 2016 | 503 | 2016 |
| Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning D Yang, H Yang, W Li, B Zhao, Z Ouyang, Z Liu, Y Zhao, N Fan, J Song, ... Cell research 21 (6), 979-982, 2011 | 224 | 2011 |
| Expression of Huntington's disease protein results in apoptotic neurons in the brains of cloned transgenic pigs D Yang, CE Wang, B Zhao, W Li, Z Ouyang, Z Liu, H Yang, P Fan, ... Human molecular genetics 19 (20), 3983-3994, 2010 | 220 | 2010 |
| Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome O Rom, Y Liu, Z Liu, Y Zhao, J Wu, A Ghrayeb, L Villacorta, Y Fan, ... Science translational medicine 12 (572), eaaz2841, 2020 | 202 | 2020 |
| Effective gene targeting in rabbits using RNA-guided Cas9 nucleases D Yang, J Xu, T Zhu, J Fan, L Lai, J Zhang, YE Chen Journal of molecular cell biology 6 (1), 97-99, 2014 | 202 | 2014 |
| Piglets cloned from induced pluripotent stem cells N Fan, J Chen, Z Shang, H Dou, G Ji, Q Zou, L Wu, L He, F Wang, K Liu, ... Cell research 23 (1), 162-166, 2013 | 144 | 2013 |
| RAG1/2 knockout pigs with severe combined immunodeficiency J Huang, X Guo, N Fan, J Song, B Zhao, Z Ouyang, Z Liu, Y Zhao, Q Yan, ... The Journal of Immunology 193 (3), 1496-1503, 2014 | 118 | 2014 |
| Efficient Gene Editing at Major CFTR Mutation Loci J Ruan, H Hirai, D Yang, L Ma, X Hou, H Jiang, H Wei, C Rajagopalan, ... Molecular Therapy-Nucleic Acids 16, 73-81, 2019 | 98 | 2019 |
| Use of the 2A peptide for generation of multi-transgenic pigs through a single round of nuclear transfer W Deng, D Yang, B Zhao, Z Ouyang, J Song, N Fan, Z Liu, Y Zhao, Q Wu, ... PloS one 6 (5), e19986, 2011 | 97 | 2011 |
| ApoE knockout rabbits: A novel model for the study of human hyperlipidemia M Niimi, D Yang, S Kitajima, B Ning, C Wang, S Li, E Liu, J Zhang, ... Atherosclerosis 245, 187-193, 2016 | 88 | 2016 |
| Species-dependent neuropathology in transgenic SOD1 pigs H Yang, G Wang, H Sun, R Shu, T Liu, CE Wang, Z Liu, Y Zhao, B Zhao, ... Cell research 24 (4), 464-481, 2014 | 72 | 2014 |
| Towards an optimized culture medium for the generation of mouse induced pluripotent stem cells J Chen, J Liu, Q Han, D Qin, J Xu, Y Chen, J Yang, H Song, D Yang, ... Journal of Biological Chemistry 285 (40), 31066-31072, 2010 | 70 | 2010 |
| Deficiency of cholesteryl ester transfer protein protects against atherosclerosis in rabbits J Zhang, M Niimi, D Yang, J Liang, J Xu, T Kimura, AV Mathew, Y Guo, ... Arteriosclerosis, thrombosis, and vascular biology 37 (6), 1068-1075, 2017 | 63 | 2017 |
| Identification and characterization of rabbit ROSA26 for gene knock-in and stable reporter gene expression D Yang, J Song, J Zhang, J Xu, T Zhu, Z Wang, L Lai, YE Chen Scientific reports 6 (1), 1-8, 2016 | 57 | 2016 |
| Trichostatin A improved epigenetic modifications of transfected cells but did not improve subsequent cloned embryo development X Wu∗, Y Li∗, GP Li, D Yang, Y Yue, L Wang, K Li, P Xin, S Bou, H Yu Animal biotechnology 19 (4), 211-224, 2008 | 55 | 2008 |
| Production of apolipoprotein C-III knockout rabbits using zinc finger nucleases D Yang, J Zhang, J Xu, T Zhu, Y Fan, J Fan, YE Chen JoVE (Journal of Visualized Experiments), e50957, 2013 | 47 | 2013 |
| Phenotypes of CF rabbits generated by CRISPR/Cas9-mediated disruption of the CFTR gene J Xu, A Livraghi-Butrico, X Hou, C Rajagopalan, J Zhang, J Song, H Jiang, ... JCI insight 6 (1), 2021 | 41 | 2021 |
| MiCas9 increases large size gene knock-in rates and reduces undesirable on-target and off-target indel edits L Ma, J Ruan, J Song, L Wen, D Yang, J Zhao, X Xia, YE Chen, J Zhang, ... Nature communications 11 (1), 1-11, 2020 | 40 | 2020 |
| Recent advances in improving gene-editing specificity through CRISPR–Cas9 nuclease engineering X Huang, D Yang, J Zhang, J Xu, YE Chen Cells 11 (14), 2186, 2022 | 36 | 2022 |
Y. Eugene CHENUniversity of MichiganBestätigte E-Mail-Adresse bei umich.edu