The role of astrocyte dysfunction in Parkinson’s disease pathogenesis HDE Booth, WD Hirst, R Wade-Martins Trends in neurosciences 40 (6), 358-370, 2017 | 610 | 2017 |
ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons HJR Fernandes, EM Hartfield, HC Christian, E Emmanoulidou, Y Zheng, ... Stem cell reports 6 (3), 342-356, 2016 | 382 | 2016 |
Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson’s iPSC-derived dopamine neurons F Zambon, M Cherubini, HJR Fernandes, C Lang, BJ Ryan, V Volpato, ... Human molecular genetics 28 (12), 2001-2013, 2019 | 158 | 2019 |
Characterizing human stem cell–derived sensory neurons at the single-cell level reveals their ion channel expression and utility in pain research GT Young, A Gutteridge, HDE Fox, AL Wilbrey, L Cao, LT Cho, AR Brown, ... Molecular Therapy 22 (8), 1530-1543, 2014 | 158 | 2014 |
Directing differentiation of human embryonic stem cells toward anterior neural ectoderm using small molecules B Surmacz, H Fox, A Gutteridge, S Lubitz, P Whiting Stem Cells 30 (9), 1875-1884, 2012 | 98 | 2012 |
Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson’s disease C Sandor, P Robertson, C Lang, A Heger, H Booth, J Vowles, L Witty, ... Human molecular genetics 26 (3), 552-566, 2017 | 85 | 2017 |
RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes HDE Booth, F Wessely, N Connor-Robson, F Rinaldi, J Vowles, C Browne, ... Neurobiology of disease 129, 56-66, 2019 | 72 | 2019 |
An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2 N Connor-Robson, H Booth, JG Martin, B Gao, K Li, N Doig, J Vowles, ... Neurobiology of disease 127, 512-526, 2019 | 72 | 2019 |
MAPT Genetic Variation and Neuronal Maturity Alter Isoform Expression Affecting Axonal Transport in iPSC-Derived Dopamine Neurons JE Beevers, MC Lai, E Collins, HDE Booth, F Zambon, L Parkkinen, ... Stem cell reports 9 (2), 587-599, 2017 | 67 | 2017 |
Method for producing retinal pigment epithelial cells P Choudhary, B Surmacz-Cordle, HDE Fox, PJ Whiting US Patent App. 14/566,184, 2015 | 18 | 2015 |
Modelling and analysis of LRRK2 mutations in iPSC-derived dopaminergic neurons and astrocytes HDE Booth University of Oxford, 2017 | 1 | 2017 |
Directing Differentiation of Human Embryonic Stem Cells Toward Anterior Neural Ectoderm Using Small Molecules (vol 30, pg 1875, 2012) B Surmacz, H Fox, A Gutteridge, P Fish, S Lubitz, P Whiting STEM CELLS 31 (7), 1446-1446, 2013 | 1 | 2013 |
Global proteomic and transcriptomic analysis of the LRRK2 G2019S mutation in iPSC-derived midbrain dopaminergic neurons J Martin, H Booth, B Gao, K Li, C Roberts, N Allaire, J Vowles, S Cowley, ... MOLECULAR & CELLULAR PROTEOMICS 16 (8), S52-S52, 2017 | | 2017 |
ER Stress and Autophagic Perturbations Lead to Elevated Extracellular a-Synuclein in GBA-N370S Parkinson’s iPSC-Derived Dopamine Neurons HJR Fernandes, EM Hartfield, HC Christian, E Emmanoulidou, Y Zheng, ... | | |