Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts BJ Hansen, J Zhao, TA Csepe, BT Moore, N Li, LA Jayne, ... European heart journal 36 (35), 2390-2401, 2015 | 444 | 2015 |
Calsequestrin 2 deletion causes sinoatrial node dysfunction and atrial arrhythmias associated with altered sarcoplasmic reticulum calcium cycling and degenerative fibrosis … AV Glukhov, A Kalyanasundaram, Q Lou, LT Hage, BJ Hansen, ... European heart journal 36 (11), 686-697, 2015 | 150 | 2015 |
Three‐dimensional integrated functional, structural, and computational mapping to define the structural “fingerprints” of heart‐specific atrial fibrillation drivers in human … J Zhao, BJ Hansen, Y Wang, TA Csepe, LV Sul, A Tang, Y Yuan, N Li, ... Journal of the American Heart Association 6 (8), e005922, 2017 | 146 | 2017 |
Fibrosis: a structural modulator of sinoatrial node physiology and dysfunction TA Csepe, A Kalyanasundaram, BJ Hansen, J Zhao, VV Fedorov Frontiers in physiology 6, 37, 2015 | 128 | 2015 |
Redundant and diverse intranodal pacemakers and conduction pathways protect the human sinoatrial node from failure N Li, BJ Hansen, TA Csepe, J Zhao, AJ Ignozzi, LV Sul, SO Zakharkin, ... Science translational medicine 9 (400), eaam5607, 2017 | 111 | 2017 |
Adenosine-induced atrial fibrillation: localized reentrant drivers in lateral right atria due to heterogeneous expression of adenosine A1 receptors and GIRK4 subunits in the … N Li, TA Csepe, BJ Hansen, LV Sul, A Kalyanasundaram, SO Zakharkin, ... Circulation 134 (6), 486-498, 2016 | 110 | 2016 |
Human sinoatrial node structure: 3D microanatomy of sinoatrial conduction pathways TA Csepe, J Zhao, BJ Hansen, N Li, LV Sul, P Lim, Y Wang, OP Simonetti, ... Progress in biophysics and molecular biology 120 (1-3), 164-178, 2016 | 110 | 2016 |
Fibrosis and atrial fibrillation: computerized and optical mapping: a view into the human atria at submillimeter resolution BJ Hansen, J Zhao, VV Fedorov JACC: Clinical Electrophysiology 3 (6), 531-546, 2017 | 106 | 2017 |
Molecular mapping of sinoatrial node HCN channel expression in the human heart N Li, TA Csepe, BJ Hansen, H Dobrzynski, RSD Higgins, A Kilic, ... Circulation: Arrhythmia and Electrophysiology 8 (5), 1219-1227, 2015 | 104 | 2015 |
Human atrial fibrillation drivers resolved with integrated functional and structural imaging to benefit clinical mapping BJ Hansen, J Zhao, N Li, A Zolotarev, S Zakharkin, Y Wang, J Atwal, ... JACC: Clinical Electrophysiology 4 (12), 1501-1515, 2018 | 92* | 2018 |
Upregulation of adenosine A1 receptors facilitates sinoatrial node dysfunction in chronic canine heart failure by exacerbating nodal conduction abnormalities revealed by novel … Q Lou, BJ Hansen, O Fedorenko, TA Csepe, A Kalyanasundaram, N Li, ... Circulation 130 (4), 315-324, 2014 | 78 | 2014 |
Rationally engineered Troponin C modulates in vivo cardiac function and performance in health and disease V Shettigar, B Zhang, SC Little, HE Salhi, BJ Hansen, N Li, J Zhang, ... Nature communications 7 (1), 10794, 2016 | 66 | 2016 |
Sinoatrial node reentry in a canine chronic left ventricular infarct model: role of intranodal fibrosis and heterogeneity of refractoriness AV Glukhov, LT Hage, BJ Hansen, A Pedraza-Toscano, P Vargas-Pinto, ... Circulation: Arrhythmia and Electrophysiology 6 (5), 984-994, 2013 | 61 | 2013 |
Integration of high-resolution optical mapping and 3-dimensional micro-computed tomographic imaging to resolve the structural basis of atrial conduction in the human heart J Zhao, BJ Hansen, TA Csepe, P Lim, Y Wang, M Williams, PJ Mohler, ... Circulation: arrhythmia and electrophysiology 8 (6), 1514-1517, 2015 | 57* | 2015 |
Maintenance of atrial fibrillation: are reentrant drivers with spatial stability the key? BJ Hansen, TA Csepe, J Zhao, AJ Ignozzi, JD Hummel, VV Fedorov Circulation: Arrhythmia and Electrophysiology 9 (10), e004398, 2016 | 55 | 2016 |
Impaired neuronal sodium channels cause intranodal conduction failure and reentrant arrhythmias in human sinoatrial node N Li, A Kalyanasundaram, BJ Hansen, EJ Artiga, R Sharma, ... Nature communications 11 (1), 512, 2020 | 49 | 2020 |
Canine and human sinoatrial node: differences and similarities in the structure, function, molecular profiles, and arrhythmia A Kalyanasundaram, N Li, BJ Hansen, J Zhao, VV Fedorov Journal of veterinary cardiology 22, 2-19, 2019 | 46 | 2019 |
Silencing miR-370-3p rescues funny current and sinus node function in heart failure J Yanni, A D’Souza, Y Wang, N Li, BJ Hansen, SO Zakharkin, M Smith, ... Scientific reports 10 (1), 11279, 2020 | 45 | 2020 |
Atrial fibrillation driver mechanisms: insight from the isolated human heart TA Csepe, BJ Hansen, VV Fedorov Trends in cardiovascular medicine 27 (1), 1-11, 2017 | 40 | 2017 |
Optical mapping-validated machine learning improves atrial fibrillation driver detection by multi-electrode mapping AM Zolotarev, BJ Hansen, EA Ivanova, KM Helfrich, N Li, PML Janssen, ... Circulation: Arrhythmia and Electrophysiology 13 (10), e008249, 2020 | 38 | 2020 |