| Generation of impossible cross-peaks between bulk water and biomolecules in solution NMR WS Warren, W Richter, AH Andreotti, BT Farmer Science 262 (5142), 2005-2009, 1993 | 469 | 1993 |
| Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A KN Brazin, RJ Mallis, DB Fulton, AH Andreotti Proceedings of the National Academy of Sciences 99 (4), 1899-1904, 2002 | 347 | 2002 |
| Regulatory intramolecular association in a tyrosine kinase of the Tec family AH Andreotti, SC Bunnell, S Feng, LJ Berg, SL Schreiber Nature 385 (6611), 93-97, 1997 | 342 | 1997 |
| Native state proline isomerization: an intrinsic molecular switch AH Andreotti Biochemistry 42 (32), 9515-9524, 2003 | 337 | 2003 |
| T-cell signaling regulated by the Tec family kinase, Itk AH Andreotti, PL Schwartzberg, RE Joseph, LJ Berg Cold Spring Harbor perspectives in biology 2 (7), a002287, 2010 | 282 | 2010 |
| Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk J Colgan, M Asmal, M Neagu, B Yu, J Schneidkraut, Y Lee, E Sokolskaja, ... Immunity 21 (2), 189-201, 2004 | 267 | 2004 |
| Structural characterization of a proline-driven conformational switch within the Itk SH2 domain RJ Mallis, KN Brazin, DB Fulton, AH Andreotti Nature structural biology 9 (12), 900-905, 2002 | 169 | 2002 |
| The effects of glycosylation on peptide backbone conformation AH Andreotti, D Kahne Journal of the American Chemical Society 115 (8), 3352-3353, 1993 | 154 | 1993 |
| Solution and Micelle-Bound Structures of Tachyplesin I and Its Active Aromatic Linear Derivatives, A Laederach, AH Andreotti, DB Fulton Biochemistry 41 (41), 12359-12368, 2002 | 145 | 2002 |
| Positive regulation of Itk PH domain function by soluble IP4 YH Huang, JA Grasis, AT Miller, R Xu, S Soonthornvacharin, AH Andreotti, ... Science 316 (5826), 886-889, 2007 | 127 | 2007 |
| A specific intermolecular association between the regulatory domains of a Tec family kinase KN Brazin, DB Fulton, AH Andreotti Journal of Molecular Biology 302 (3), 607-623, 2000 | 110 | 2000 |
| Sensitivity of glycopeptide conformation to carbohydrate chain length. R Liang, AH Andreotti, D Kahne Journal of the American Chemical Society 117 (41), 10395-10396, 1995 | 82 | 1995 |
| Bacterial expression and purification of interleukin-2 tyrosine kinase: single step separation of the chaperonin impurity RE Joseph, AH Andreotti Protein expression and purification 60 (2), 194-197, 2008 | 76 | 2008 |
| The linker between SH2 and kinase domains positively regulates catalysis of the Tec family kinases RE Joseph, L Min, AH Andreotti Biochemistry 46 (18), 5455-5462, 2007 | 70 | 2007 |
| Exploring the specificity pockets of two homologous SH3 domains using structure-based, split-pool synthesis and affinity-based selection TM Kapoor, AH Andreotti, SL Schreiber Journal of the American Chemical Society 120 (1), 23-29, 1998 | 62 | 1998 |
| Dynamic allostery mediated by a conserved tryptophan in the Tec family kinases N Chopra, TE Wales, RE Joseph, SE Boyken, JR Engen, RL Jernigan, ... PLoS computational biology 12 (3), e1004826, 2016 | 59 | 2016 |
| Competing modes of self‐association in the regulatory domains of Bruton's tyrosine kinase: intramolecular contact versus asymmetric homodimerization A Laederach, KW Cradic, KN Brazin, J Zamoon, DB Fulton, XY Huang, ... Protein science 11 (1), 36-57, 2002 | 57 | 2002 |
| Achieving a graded immune response: BTK adopts a range of active/inactive conformations dictated by multiple interdomain contacts RE Joseph, TE Wales, DB Fulton, JR Engen, AH Andreotti Structure 25 (10), 1481-1494. e4, 2017 | 56 | 2017 |
| Molecular details of Itk activation by prolyl isomerization and phospholigand binding: the NMR structure of the Itk SH2 domain bound to a phosphopeptide EV Pletneva, M Sundd, DB Fulton, AH Andreotti Journal of molecular biology 357 (2), 550-561, 2006 | 55 | 2006 |
| Ligand specificity modulated by prolyl imide bond cis/trans isomerization in the Itk SH2 domain: a quantitative NMR study PJ Breheny, A Laederach, DB Fulton, AH Andreotti Journal of the American Chemical Society 125 (51), 15706-15707, 2003 | 55 | 2003 |
