Microfabricated mammalian organ systems and their integration into models of whole animals and humans JH Sung, MB Esch, JM Prot, CJ Long, A Smith, JJ Hickman, ML Shuler Lab on a Chip 13 (7), 1201-1212, 2013 | 287 | 2013 |
Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow MB Esch, JM Prot, YI Wang, P Miller, JR Llamas-Vidales, BA Naughton, ... Lab on a Chip 15 (10), 2269-2277, 2015 | 189 | 2015 |
How multi-organ microdevices can help foster drug development MB Esch, AST Smith, JM Prot, C Oleaga, JJ Hickman, ML Shuler Advanced drug delivery reviews 69, 158-169, 2014 | 173 | 2014 |
Behavior of HepG2/C3A cell cultures in a microfluidic bioreactor R Baudoin, L Griscom, JM Prot, C Legallais, E Leclerc Biochemical Engineering Journal 53 (2), 172-181, 2011 | 129 | 2011 |
Metabolomics-on-a-chip and predictive systems toxicology in microfluidic bioartificial organs L Shintu, R Baudoin, V Navratil, JM Prot, C Pontoizeau, M Defernez, ... Analytical chemistry 84 (4), 1840-1848, 2012 | 116 | 2012 |
Improvement of HepG2/C3a cell functions in a microfluidic biochip JM Prot, C Aninat, L Griscom, F Razan, C Brochot, CG Guillouzo, ... Biotechnology and bioengineering 108 (7), 1704-1715, 2011 | 105 | 2011 |
First pass intestinal and liver metabolism of paracetamol in a microfluidic platform coupled with a mathematical modeling as a means of evaluating ADME processes in humans JM Prot, L Maciel, T Bricks, F Merlier, J Cotton, P Paullier, FY Bois, ... Biotechnology and bioengineering 111 (10), 2027-2040, 2014 | 91 | 2014 |
Predictive toxicology using systemic biology and liver microfluidic “on chip” approaches: application to acetaminophen injury JM Prot, A Bunescu, B Elena-Herrmann, C Aninat, LC Snouber, L Griscom, ... Toxicology and applied pharmacology 259 (3), 270-280, 2012 | 82 | 2012 |
A cocktail of metabolic probes demonstrates the relevance of primary human hepatocyte cultures in a microfluidic biochip for pharmaceutical drug screening JM Prot, O Videau, C Brochot, C Legallais, H Benech, E Leclerc International journal of pharmaceutics 408 (1-2), 67-75, 2011 | 73 | 2011 |
A phenotypic in vitro model for the main determinants of human whole heart function M Stancescu, P Molnar, CW McAleer, W McLamb, CJ Long, C Oleaga, ... Biomaterials 60, 20-30, 2015 | 68 | 2015 |
Metabolomics-on-a-chip and metabolic flux analysis for label-free modeling of the internal metabolism of HepG2/C3A cells DA Ouattara, JM Prot, A Bunescu, ME Dumas, B Elena-Herrmann, ... Molecular bioSystems 8 (7), 1908-1920, 2012 | 52 | 2012 |
Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips R Baudoin, JM Prot, G Nicolas, J Brocheton, C Brochot, C Legallais, ... Xenobiotica 43 (2), 140-152, 2013 | 47 | 2013 |
Integrated proteomic and transcriptomic investigation of the acetaminophen toxicity in liver microfluidic biochip JM Prot, AS Briffaut, F Letourneur, P Chafey, F Merlier, Y Grandvalet, ... PLoS One 6 (8), e21268, 2011 | 47 | 2011 |
Microphysiological systems and low-cost microfluidic platform with analytics AST Smith, CJ Long, BJ Berry, C McAleer, M Stancescu, P Molnar, ... Stem cell research & therapy 4, 1-5, 2013 | 35 | 2013 |
Zonation related function and ubiquitination regulation in human hepatocellular carcinoma cells in dynamic vs. static culture conditions S Cheng, JM Prot, E Leclerc, FY Bois BMC genomics 13, 1-10, 2012 | 28 | 2012 |
The current status of alternatives to animal testing and predictive toxicology methods using liver microfluidic biochips JM Prot, E Leclerc Annals of biomedical engineering 40, 1228-1243, 2012 | 28 | 2012 |
Piezoelectric bioMEMS cantilever for measurement of muscle contraction and for actuation of mechanosensitive cells EA Coln, A Colon, CJ Long, NN Sriram, M Esch, JM Prot, DH Elbrecht, ... MRS communications 9, 1186-1192, 2019 | 12 | 2019 |
Benchmark des services biomédicaux: vision médiane et diversité de la maintenance hospitalière… G Farges, I Claude, JM Prot, PM Félan IRBM News 40 (5), 100200, 2019 | 5 | 2019 |
Qualité opérationnelle pour les laboratoires avec le «5S Biologie» N Drillaud, C Siaka, A Khalil, L Yin, JM Prot, JP Caliste, G Farges IRBM News 38 (1), 82-86, 2017 | 4 | 2017 |
‘Body-on-a-Chip’Technology and Supporting Microfluidics AST Smith, CJ Long, C McAleer, X Guo, M Esch, JM Prot, ML Shuler, ... | 4 | 2014 |