Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin Y Wang, W Gao, X Shi, J Ding, W Liu, H He, K Wang, F Shao Nature 547 (7661), 99-103, 2017 | 2507 | 2017 |
Pore-forming activity and structural autoinhibition of the gasdermin family J Ding, K Wang, W Liu, Y She, Q Sun, J Shi, H Sun, DC Wang, F Shao Nature 535 (7610), 111-116, 2016 | 2455 | 2016 |
Inflammatory caspases are innate immune receptors for intracellular LPS J Shi, Y Zhao, Y Wang, W Gao, J Ding, P Li, L Hu, F Shao Nature 514 (7521), 187-192, 2014 | 2285 | 2014 |
Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells Z Zhou, H He, K Wang, X Shi, Y Wang, Y Su, Y Wang, D Li, W Liu, ... Science 368 (6494), eaaz7548, 2020 | 1042 | 2020 |
A bioorthogonal system reveals antitumour immune function of pyroptosis Q Wang, Y Wang, J Ding, C Wang, X Zhou, W Gao, H Huang, F Shao, ... Nature 579 (7799), 421-426, 2020 | 785 | 2020 |
Structural mechanism for GSDMD targeting by autoprocessed caspases in pyroptosis K Wang, QI Sun, X Zhong, M Zeng, H Zeng, X Shi, Z Li, Y Wang, Q Zhao, ... Cell 180 (5), 941-955. e20, 2020 | 564 | 2020 |
A bacterial effector reveals the V-ATPase-ATG16L1 axis that initiates xenophagy Y Xu, P Zhou, S Cheng, Q Lu, K Nowak, AK Hopp, L Li, X Shi, Z Zhou, ... Cell 178 (3), 552-566. e20, 2019 | 304 | 2019 |
Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose P Zhou, Y She, N Dong, P Li, H He, A Borio, Q Wu, S Lu, X Ding, Y Cao, ... Nature 561 (7721), 122-126, 2018 | 236 | 2018 |
Shigella evades pyroptosis by arginine ADP-riboxanation of caspase-11 Z Li, W Liu, J Fu, S Cheng, Y Xu, Z Wang, X Liu, X Shi, Y Liu, X Qi, X Liu, ... Nature 599 (7884), 290-295, 2021 | 153 | 2021 |
Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins H Feng, J Ding, D Zhu, X Liu, X Xu, Y Zhang, S Zang, DC Wang, W Liu Journal of the American Chemical Society 136 (42), 14694-14697, 2014 | 127 | 2014 |
SnapShot: the noncanonical inflammasome J Ding, F Shao Cell 168 (3), 544-544. e1, 2017 | 109 | 2017 |
Structural basis of the ultrasensitive calcium indicator GCaMP6 JJ Ding, AF Luo, LY Hu, DC Wang, F Shao Science china life sciences 57, 269-274, 2014 | 86 | 2014 |
Structural mechanisms for regulation of GSDMB pore-forming activity X Zhong, H Zeng, Z Zhou, Y Su, H Cheng, Y Hou, Y She, N Feng, J Wang, ... Nature 616 (7957), 598-605, 2023 | 84 | 2023 |
Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome X Shi, Q Sun, Y Hou, H Zeng, Y Cao, M Dong, J Ding, F Shao Nature 624 (7991), 442-450, 2023 | 58 | 2023 |
Structural insights into the Pseudomonas aeruginosa type VI virulence effector Tse1 bacteriolysis and self-protection mechanisms J Ding, W Wang, H Feng, Y Zhang, DC Wang Journal of Biological Chemistry 287 (32), 26911-26920, 2012 | 56 | 2012 |
ARF GTPases activate Salmonella effector SopF to ADP-ribosylate host V-ATPase and inhibit endomembrane damage-induced autophagy Y Xu, S Cheng, H Zeng, P Zhou, Y Ma, L Li, X Liu, F Shao, J Ding Nature Structural & Molecular Biology 29 (1), 67-77, 2022 | 51 | 2022 |
Structural and functional insights into host death domains inactivation by the bacterial arginine GlcNAcyltransferase effector J Ding, X Pan, L Du, Q Yao, J Xue, H Yao, DC Wang, S Li, F Shao Molecular cell 74 (5), 922-935. e6, 2019 | 47 | 2019 |
Crystal structures of a novel anti-HIV mannose-binding lectin from Polygonatum cyrtonema Hua with unique ligand-binding property and super-structure J Ding, J Bao, D Zhu, Y Zhang, DC Wang Journal of structural Biology 171 (3), 309-317, 2010 | 44 | 2010 |
Structural mechanism governing the quaternary organization of monocot mannose-binding lectin revealed by the novel monomeric structure of an orchid lectin W Liu, N Yang, J Ding, R Huang, Z Hu, DC Wang Journal of Biological Chemistry 280 (15), 14865-14876, 2005 | 41 | 2005 |
Structural insights into the molecular recognition between cerebral cavernous malformation 2 and mitogen-activated protein kinase kinase kinase 3 X Wang, Y Hou, K Deng, Y Zhang, DC Wang, J Ding Structure 23 (6), 1087-1096, 2015 | 35 | 2015 |