| Acute rheumatic fever and rheumatic heart disease JR Carapetis, A Beaton, MW Cunningham, L Guilherme, G Karthikeyan, ... Nature reviews Disease primers 2 (1), 1-24, 2016 | 666 | 2016 |
| The epidemiology of sepsis in Brazilian intensive care units (the Sepsis PREvalence Assessment Database, SPREAD): an observational study FR Machado, AB Cavalcanti, FA Bozza, EM Ferreira, FSA Carrara, ... The Lancet Infectious Diseases 17 (11), 1180-1189, 2017 | 406 | 2017 |
| Autoimmunity in Chagas' disease. Identification of cardiac myosin-B13 Trypanosoma cruzi protein crossreactive T cell clones in heart lesions of a chronic Chagas' cardiomyopathy … E Cunha-Neto, V Coelho, L Guilherme, A Fiorelli, N Stolf, J Kalil The Journal of clinical investigation 98 (8), 1709-1712, 1996 | 283 | 1996 |
| Human heart–infiltrating T-Cell clones from rheumatic heart disease patients recognize both streptococcal and cardiac proteins L Guilherme, E Cunha-Neto, V Coelho, R Snitcowsky, PMA Pomerantzeff, ... Circulation 92 (3), 415-420, 1995 | 280 | 1995 |
| Molecular mimicry in the autoimmune pathogenesis of rheumatic heart disease L Guilherme, J Kalil, M Cunningham Autoimmunity 39 (1), 31-39, 2006 | 259 | 2006 |
| Rheumatic heart disease: proinflammatory cytokines play a role in the progression and maintenance of valvular lesions L Guilherme, P Cury, LMF Demarchi, V Coelho, L Abel, AP Lopez, ... The American journal of pathology 165 (5), 1583-1591, 2004 | 257 | 2004 |
| Rheumatic fever and rheumatic heart disease: cellular mechanisms leading autoimmune reactivity and disease L Guilherme, J Kalil Journal of clinical immunology 30, 17-23, 2010 | 243 | 2010 |
| Acute rheumatic fever G Karthikeyan, L Guilherme The Lancet 392 (10142), 161-174, 2018 | 232 | 2018 |
| Rheumatic fever and rheumatic heart disease: genetics and pathogenesis L Guilherme, R Ramasawmy, J Kalil Scandinavian journal of immunology 66 (2‐3), 199-207, 2007 | 201 | 2007 |
| Mimicry in recognition of cardiac myosin peptides by heart-intralesional T cell clones from rheumatic heart disease KC Faé, DD da Silva, SE Oshiro, AC Tanaka, P Pomerantzeff, C Douay, ... The Journal of Immunology 176 (9), 5662-5670, 2006 | 184 | 2006 |
| Association of human leukocyte class II antigens with rheumatic fever or rheumatic heart disease in a Brazilian population. L Guilherme, W Weidebach, MH Kiss, R Snitcowsky, J Kalil Circulation 83 (6), 1995-1998, 1991 | 177 | 1991 |
| Status of research and development of vaccines for Streptococcus pyogenes AC Steer, JR Carapetis, JB Dale, JD Fraser, MF Good, L Guilherme, ... Vaccine 34 (26), 2953-2958, 2016 | 174 | 2016 |
| T-cell reactivity against streptococcal antigens in the periphery mirrors reactivity of heart-infiltrating T lymphocytes in rheumatic heart disease patients L Guilherme, SE Oshiro, KC Faé, E Cunha-Neto, G Renesto, AC Goldberg, ... Infection and Immunity 69 (9), 5345-5351, 2001 | 138 | 2001 |
| Molecular pathogenesis of rheumatic fever and rheumatic heart disease L Guilherme, K Faé, SE Oshiro, J Kalil Expert reviews in molecular medicine 7 (28), 1-15, 2005 | 121 | 2005 |
| Immunological balance is associated with clinical outcome after autologous hematopoietic stem cell transplantation in type 1 diabetes KCR Malmegrim, JLTC De Azevedo, LCM Arruda, JRF Abreu, CEB Couri, ... Frontiers in immunology 8, 167, 2017 | 99 | 2017 |
| Association of polymorphisms within the promoter region of the tumor necrosis factor-α with clinical outcomes of rheumatic fever R Ramasawmy, KC Faé, G Spina, GD Victora, AC Tanaka, SA Palácios, ... Molecular immunology 44 (8), 1873-1878, 2007 | 99 | 2007 |
| Genes, autoimmunity and pathogenesis of rheumatic heart disease L Guilherme, KF Köhler, E Postol, J Kalil Annals of pediatric cardiology 4 (1), 13-21, 2011 | 97 | 2011 |
| Cytokine production profile of heart-infiltrating T cells in Chagas' disease cardiomyopathy E Cunha-Neto, LV Rizzo, F Albuquerque, L Abel, L Guilherme, E Bocchi, ... Brazilian Journal of Medical and Biological Research 31, 133-137, 1998 | 93 | 1998 |
| Towards a vaccine against rheumatic fever L Guilherme, KC Faé, F Higa, L Chaves, SE Oshiro, SF De Barros, ... Journal of Immunology Research 13 (2-4), 125-132, 2006 | 92 | 2006 |
| How an autoimmune reaction triggered by molecular mimicry between streptococcal M protein and cardiac tissue proteins leads to heart lesions in rheumatic heart disease KC Fae, SE Oshiro, A Toubert, D Charron, J Kalil, L Guilherme Journal of autoimmunity 24 (2), 101-109, 2005 | 92 | 2005 |
