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Marcin Poreba
Marcin Poreba
Wroclaw University of Science and Technology
Bestätigte E-Mail-Adresse bei pwr.edu.pl - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Caspase substrates and inhibitors
M Poręba, A Stróżyk, GS Salvesen, M Drąg
Cold Spring Harbor perspectives in biology 5 (8), a008680, 2013
276*2013
Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling
P Kasperkiewicz, M Poreba, SJ Snipas, H Parker, CC Winterbourn, ...
Proceedings of the National Academy of Sciences 111 (7), 2518-2523, 2014
1732014
Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides
E Zervoudi, A Papakyriakou, D Georgiadou, I Evnouchidou, A Gajda, ...
Biochemical Journal 435 (2), 411-420, 2011
1222011
Protease‐activated prodrugs: strategies, challenges, and future directions
M Poreba
The FEBS journal 287 (10), 1936-1969, 2020
1172020
Mechanism and specificity of the human paracaspase MALT1
J Hachmann, SJ Snipas, BJ van Raam, EM Cancino, EJ Houlihan, ...
Biochemical Journal 443 (1), 287-295, 2012
1092012
Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1
MLG Ramirez, M Poreba, SJ Snipas, K Groborz, M Drag, GS Salvesen
Journal of Biological Chemistry 293 (18), 7058-7067, 2018
972018
Synthesis of a HyCoSuL peptide substrate library to dissect protease substrate specificity
M Poreba, GS Salvesen, M Drag
Nature protocols 12 (10), 2189-2214, 2017
952017
Small molecule active site directed tools for studying human caspases
M Poreba, A Szalek, P Kasperkiewicz, W Rut, GS Salvesen, M Drag
Chemical reviews 115 (22), 12546-12629, 2015
902015
Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum
M Poreba, S McGowan, TS Skinner-Adams, KR Trenholme, DL Gardiner, ...
PLoS One 7 (2), e31938, 2012
892012
Unnatural amino acids increase sensitivity and provide for the design of highly selective caspase substrates
M Poreba, P Kasperkiewicz, SJ Snipas, D Fasci, GS Salvesen, M Drag
Cell Death & Differentiation 21 (9), 1482-1492, 2014
862014
Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad
E Zeiler, A List, F Alte, M Gersch, R Wachtel, M Poreba, M Drag, M Groll, ...
Proceedings of the National Academy of Sciences 110 (28), 11302-11307, 2013
772013
Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes
M Poreba, W Rut, M Vizovisek, K Groborz, P Kasperkiewicz, D Finlay, ...
Chemical Science 9 (8), 2113-2129, 2018
742018
Highly sensitive and adaptable fluorescence-quenched pair discloses the substrate specificity profiles in diverse protease families
M Poreba, A Szalek, W Rut, P Kasperkiewicz, I Rutkowska-Wlodarczyk, ...
Scientific reports 7 (1), 1-13, 2017
742017
Fluorescent probes towards selective cathepsin B detection and visualization in cancer cells and patient samples
M Poreba, K Groborz, M Vizovisek, M Maruggi, D Turk, B Turk, G Powis, ...
Chemical science 10 (36), 8461-8477, 2019
672019
Current strategies for probing substrate specificity of proteases
M Poreba, M Drag
Current medicinal chemistry 17 (33), 3968-3995, 2010
642010
Extended substrate specificity and first potent irreversible inhibitor/activity-based probe design for Zika virus NS2B-NS3 protease
W Rut, L Zhang, P Kasperkiewicz, M Poreba, R Hilgenfeld, M Drąg
Antiviral research 139, 88-94, 2017
622017
Design of a selective substrate and activity based probe for human neutrophil serine protease 4
P Kasperkiewicz, M Poreba, SJ Snipas, SJ Lin, D Kirchhofer, ...
PLoS One 10 (7), e0132818, 2015
622015
Counter selection substrate library strategy for developing specific protease substrates and probes
M Poreba, R Solberg, W Rut, NN Lunde, P Kasperkiewicz, SJ Snipas, ...
Cell chemical biology 23 (8), 1023-1035, 2016
612016
Emerging challenges in the design of selective substrates, inhibitors and activity‐based probes for indistinguishable proteases
P Kasperkiewicz, M Poreba, K Groborz, M Drag
The FEBS journal 284 (10), 1518-1539, 2017
602017
Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45)
M Drąg-Zalesińska, M Drąg, M Poręba, S Borska, J Kulbacka, J Saczko
Cancer Cell International 17, 1-7, 2017
582017
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