| MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 V La Rosa, G Poce, JO Canseco, S Buroni, MR Pasca, M Biava, RM Raju, ... Antimicrobial agents and chemotherapy 56 (1), 324-331, 2012 | 244 | 2012 |
| Synthesis, biological evaluation, and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis: Part 2. Synthesis of rigid pyrazolones D Castagnolo, F Manetti, M Radi, B Bechi, M Pagano, A De Logu, ... Bioorganic & medicinal chemistry 17 (15), 5716-5721, 2009 | 209 | 2009 |
| Synthesis, biological evaluation and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis D Castagnolo, A De Logu, M Radi, B Bechi, F Manetti, M Magnani, ... Bioorganic & medicinal chemistry 16 (18), 8587-8591, 2008 | 177 | 2008 |
| Antimycobacterial agents. Novel diarylpyrrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity M Biava, GC Porretta, G Poce, S Supino, D Deidda, R Pompei, P Molicotti, ... Journal of medicinal chemistry 49 (16), 4946-4952, 2006 | 156 | 2006 |
| Synthesis, Biological Evaluation, and Pharmacophore Generation of New Pyridazinone Derivatives with Affinity toward α1-and α2-Adrenoceptors 1 R Barbaro, L Betti, M Botta, F Corelli, G Giannaccini, L Maccari, F Manetti, ... Journal of medicinal chemistry 44 (13), 2118-2132, 2001 | 152 | 2001 |
| LIM kinases are attractive targets with many macromolecular partners and only a few small molecule regulators F Manetti Medicinal research reviews 32 (5), 968-998, 2012 | 140 | 2012 |
| Antimycobacterial compounds. New pyrrole derivatives of BM212 M Biava, GC Porretta, D Deidda, R Pompei, A Tafi, F Manetti Bioorganic & medicinal chemistry 12 (6), 1453-1458, 2004 | 125 | 2004 |
| Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection G Poce, RH Bates, S Alfonso, M Cocozza, GC Porretta, L Ballell, J Rullas, ... PLoS One 8 (2), e56980, 2013 | 116 | 2013 |
| New pyrazolo [3, 4-d] pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation S Schenone, O Bruno, A Ranise, F Bondavalli, C Brullo, P Fossa, L Mosti, ... Bioorganic & medicinal chemistry letters 14 (10), 2511-2517, 2004 | 116 | 2004 |
| Pyrazolo [3, 4-d] pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation F Carraro, A Naldini, A Pucci, GA Locatelli, G Maga, S Schenone, O Bruno, ... Journal of medicinal chemistry 49 (5), 1549-1561, 2006 | 114 | 2006 |
| Fibroblast growth factors and their inhibitors F Manetti, F Corelli, M Botta Current pharmaceutical design 6 (18), 1897-1924, 2000 | 112 | 2000 |
| Toward the Discovery of Novel Anti‐HIV Drugs. Second‐Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti‐HIV Activity: Synthesis, Structure–Activity … G Maga, F Falchi, M Radi, L Botta, G Casaluce, M Bernardini, H Irannejad, ... ChemMedChem 6 (8), 1371-1389, 2011 | 110 | 2011 |
| 1, 5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings M Biava, GC Porretta, G Poce, A De Logu, M Saddi, R Meleddu, F Manetti, ... Journal of medicinal chemistry 51 (12), 3644-3648, 2008 | 110 | 2008 |
| Identification of a Novel Pyrazolo[3,4-d]pyrimidine Able To Inhibit Cell Proliferation of a Human Osteogenic Sarcoma in Vitro and in a Xenograft Model in Mice F Manetti, A Santucci, GA Locatelli, G Maga, A Spreafico, T Serchi, ... Journal of medicinal chemistry 50 (23), 5579-5588, 2007 | 109 | 2007 |
| Importance of the thiomorpholine introduction in new pyrrole derivatives as antimycobacterial agents analogues of BM 212 M Biava, GC Porretta, D Deidda, R Pompei, A Tafi, F Manetti Bioorganic & medicinal chemistry 11 (4), 515-520, 2003 | 109 | 2003 |
| Antifungal Agents. 10. New Derivatives of 1-[(Aryl)[4-aryl-1 H-pyrrol-3-yl] methyl]-1 H-imidazole, Synthesis, Anti-Candida Activity, and Quantitative Structure-Analysis … A Tafi, R Costi, M Botta, R Di Santo, F Corelli, S Massa, A Ciacci, ... Journal of medicinal chemistry 45 (13), 2720-2732, 2002 | 109 | 2002 |
| Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: towards the next generation HIV-1 inhibitors M Radi, F Falchi, A Garbelli, A Samuele, V Bernardo, S Paolucci, ... Bioorganic & medicinal chemistry letters 22 (5), 2094-2098, 2012 | 104 | 2012 |
| Pharmacophore Modeling and Molecular Docking Led to the Discovery of Inhibitors of Human Immunodeficiency Virus-1 Replication Targeting the Human Cellular Aspartic Acid … G Maga, F Falchi, A Garbelli, A Belfiore, M Witvrouw, F Manetti, M Botta Journal of medicinal chemistry 51 (21), 6635-6638, 2008 | 103 | 2008 |
| Computational comparison of microtubule-stabilising agents laulimalide and peloruside with taxol and colchicine O Pineda, J Farràs, L Maccari, F Manetti, M Botta, J Vilarrasa Bioorganic & medicinal chemistry letters 14 (19), 4825-4829, 2004 | 103 | 2004 |
| Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity A Solinas, H Faure, H Roudaut, E Traiffort, A Schoenfelder, A Mann, ... Journal of medicinal chemistry 55 (4), 1559-1571, 2012 | 102 | 2012 |
Giovanni MagaIGM CNRBestätigte E-Mail-Adresse bei igm.cnr.it