Algorithm for optimized mRNA design improves stability and immunogenicity H Zhang, L Zhang, A Lin, C Xu, Z Li, K Liu, B Liu, X Ma, F Zhao, H Jiang, ... Nature 621 (7978), 396-403, 2023 | 228 | 2023 |
LinearPartition: linear-time approximation of RNA folding partition function and base-pairing probabilities H Zhang, L Zhang, DH Mathews, L Huang Bioinformatics 36 (Supplement_1), i258-i267, 2020 | 76 | 2020 |
Analysis and visualization of spatial transcriptomic data B Liu, Y Li, L Zhang Frontiers in Genetics 12, 785290, 2022 | 65 | 2022 |
CoV-Seq, a new tool for SARS-CoV-2 genome analysis and visualization: Development and usability study B Liu, K Liu, H Zhang, L Zhang, Y Bian, L Huang Journal of medical Internet research 22 (10), e22299, 2020 | 34* | 2020 |
LinearTurboFold: linear-time global prediction of conserved structures for RNA homologs with applications to SARS-CoV-2 S Li, H Zhang, L Zhang, K Liu, B Liu, DH Mathews, L Huang Proceedings of the National Academy of Sciences 118 (52), e2116269118, 2021 | 26 | 2021 |
ThreshKnot: Thresholded ProbKnot for improved RNA secondary structure prediction L Zhang, H Zhang, DH Mathews, L Huang arXiv preprint arXiv:1912.12796, 2019 | 16 | 2019 |
LazySampling and LinearSampling: fast stochastic sampling of RNA secondary structure with applications to SARS-CoV-2 H Zhang, S Li, L Zhang, DH Mathews, L Huang Nucleic acids research 51 (2), e7-e7, 2023 | 8* | 2023 |
Linear-time algorithms for RNA structure prediction H Zhang, L Zhang, K Liu, S Li, DH Mathews, L Huang RNA Structure Prediction, 15-34, 2022 | 5 | 2022 |
LinearCoFold and LinearCoPartition: linear-time algorithms for secondary structure prediction of interacting RNA molecules H Zhang, S Li, N Dai, L Zhang, DH Mathews, L Huang Nucleic Acids Research 51 (18), e94-e94, 2023 | 3 | 2023 |
Improving the Circularization Efficiency, Stability and Translatability of Circular RNA by circDesign C Xu, L Zhang, W Wang, Y Tang, Q Wang, J An, H Xu, Y Ge, H Zhu, ... bioRxiv, 2023.07. 09.548293, 2023 | 3 | 2023 |
m6A-modified cenRNA stabilizes CENPA to ensure centromere integrity in cancer cells Z Kang, R Li, C Liu, X Dong, Y Hu, L Xu, X Liu, Y Xiang, L Gao, W Si, ... Cell 187 (21), 6035-6054. e27, 2024 | 2 | 2024 |
LinearAlifold: Linear-time consensus structure prediction for RNA alignments A Malik, L Zhang, M Gautam, N Dai, S Li, H Zhang, DH Mathews, L Huang Journal of Molecular Biology 436 (17), 168694, 2024 | 1 | 2024 |
A nucleoside-modified rabies mRNA vaccine induces long-lasting and comprehensive immune responses in mice and non-human primates Y Wang, S Wang, L Huang, W Mao, F Li, A Lin, W Zhao, X Zeng, Y Zhang, ... Molecular Therapy, 2024 | | 2024 |
Systems and Methods for Sequence Design H Zhang, L Zhang, Z Li, K Liu, B Liu, L Huang US Patent App. 18/795,898, 2024 | | 2024 |
siRNADiscovery: a graph neural network for siRNA efficacy prediction via deep RNA sequence analysis R Long, Z Guo, D Han, B Liu, X Yuan, G Chen, PA Heng, L Zhang Briefings in Bioinformatics 25 (6), bbae563, 2024 | | 2024 |
Systems and methods for sequence design H Zhang, L Zhang, Z Li, LIU Kaibo, LIU Boxiang, L Huang US Patent App. 17/184,505, 2022 | | 2022 |
Systems and methods for genome analysis and visualization LIU Boxiang, LIU Kaibo, H Zhang, L Zhang, Y Bian, L Huang US Patent App. 17/065,233, 2022 | | 2022 |
Cross Protection and Sustained Immunity Against Influenza a Viruses in Mice Provided by Core-Shell Structured Lipopolyplex Delivered mRNA Vaccine with Optimized Sequences … T Wang, R Han, Z Hao, X Cheng, J Li, C Zhai, D Wang, Y Deng, L Zhang, ... Available at SSRN 5083848, 0 | | |