Global Initiative for Asthma Strategy 2021: executive summary and rationale for key changes HK Reddel, LB Bacharier, ED Bateman, CE Brightling, GG Brusselle, ... American journal of respiratory and critical care medicine 205 (1), 17-35, 2022 | 1071 | 2022 |
Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort DE Shaw, AR Sousa, SJ Fowler, LJ Fleming, G Roberts, J Corfield, ... European Respiratory Journal 46 (5), 1308-1321, 2015 | 627 | 2015 |
GINA 2019: a fundamental change in asthma management: treatment of asthma with short-acting bronchodilators alone is no longer recommended for adults and adolescents HK Reddel, JM FitzGerald, ED Bateman, LB Bacharier, A Becker, ... European Respiratory Journal 53 (6), 2019 | 464 | 2019 |
Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI) EH Bel, A Sousa, L Fleming, A Bush, KF Chung, J Versnel, AH Wagener, ... Thorax 66 (10), 910-917, 2011 | 394 | 2011 |
Pediatric severe asthma is characterized by eosinophilia and remodeling without TH2 cytokines CJ Bossley, L Fleming, A Gupta, N Regamey, J Frith, T Oates, L Tsartsali, ... Journal of Allergy and Clinical Immunology 129 (4), 974-982. e13, 2012 | 388 | 2012 |
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics D Lefaudeux, B De Meulder, MJ Loza, N Peffer, A Rowe, F Baribaud, ... Journal of Allergy and Clinical Immunology 139 (6), 1797-1807, 2017 | 314 | 2017 |
The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts L Fleming, C Murray, AT Bansal, S Hashimoto, H Bisgaard, A Bush, ... European Respiratory Journal 46 (5), 1322-1333, 2015 | 254 | 2015 |
The importance of nurse-led home visits in the assessment of children with problematic asthma M Bracken, L Fleming, P Hall, N Van Stiphout, C Bossley, E Biggart, ... Archives of disease in childhood 94 (10), 780-784, 2009 | 244 | 2009 |
Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33 S Castanhinha, R Sherburn, S Walker, A Gupta, CJ Bossley, J Buckley, ... Journal of Allergy and Clinical Immunology 136 (2), 312-322. e7, 2015 | 220 | 2015 |
Key recommendations for primary care from the 2022 Global Initiative for Asthma (GINA) update ML Levy, LB Bacharier, E Bateman, LP Boulet, C Brightling, R Buhl, ... NPJ primary care respiratory medicine 33 (1), 1-13, 2023 | 215 | 2023 |
Sputum inflammatory phenotypes are not stable in children with asthma L Fleming, L Tsartsali, N Wilson, N Regamey, A Bush Thorax 67 (8), 675-681, 2012 | 209 | 2012 |
A transcriptome-driven analysis of epithelial brushings and bronchial biopsies to define asthma phenotypes in U-BIOPRED CHS Kuo, S Pavlidis, M Loza, F Baribaud, A Rowe, I Pandis, U Hoda, ... American journal of respiratory and critical care medicine 195 (4), 443-455, 2017 | 198 | 2017 |
Increased airway smooth muscle mass in children with asthma, cystic fibrosis, and non-cystic fibrosis bronchiectasis N Regamey, M Ochs, TN Hilliard, C Mühlfeld, N Cornish, L Fleming, ... American journal of respiratory and critical care medicine 177 (8), 837-843, 2008 | 196 | 2008 |
Measurement of bronchial and alveolar nitric oxide production in normal children and children with asthma E Paraskakis, C Brindicci, L Fleming, R Krol, SA Kharitonov, NM Wilson, ... American journal of respiratory and critical care medicine 174 (3), 260-267, 2006 | 196 | 2006 |
Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation Z Jevnikar, J Östling, E Ax, J Calvén, K Thörn, E Israelsson, L Öberg, ... Journal of Allergy and Clinical Immunology 143 (2), 577-590, 2019 | 172 | 2019 |
Type 2 innate lymphoid cells in induced sputum from children with severe asthma P Nagakumar, L Denney, L Fleming, A Bush, CM Lloyd, S Saglani Journal of Allergy and Clinical Immunology 137 (2), 624-626. e6, 2016 | 169 | 2016 |
“T2-high” in severe asthma related to blood eosinophil, exhaled nitric oxide and serum periostin S Pavlidis, K Takahashi, FNK Kwong, J Xie, U Hoda, K Sun, ... European Respiratory Journal 53 (1), 2019 | 167 | 2019 |
Advances in understanding and reducing the burden of severe asthma in children MW Pijnenburg, L Fleming The Lancet Respiratory Medicine 8 (10), 1032-1044, 2020 | 146 | 2020 |
Use of sputum eosinophil counts to guide management in children with severe asthma L Fleming, N Wilson, N Regamey, A Bush Thorax 67 (3), 193-198, 2012 | 144 | 2012 |
Blood eosinophil counts rarely reflect airway eosinophilia in children with severe asthma N Ullmann, CJ Bossley, L Fleming, M Silvestri, A Bush, S Saglani Allergy 68 (3), 402-406, 2013 | 136 | 2013 |