| NMR characterization of hairpin polyamide complexes with the minor groove of DNA RPL De Clairac, BH Geierstanger, M Mrksich, PB Dervan, DE Wemmer Journal of the American Chemical Society 119 (34), 7909-7916, 1997 | 152 | 1997 |
| Further naphthylcombretastatins. An investigation on the role of the naphthalene moiety ABS Maya, C Pérez-Melero, C Mateo, D Alonso, JL Fernández, C Gajate, ... Journal of medicinal chemistry 48 (2), 556-568, 2005 | 144 | 2005 |
| A new family of quinoline and quinoxaline analogues of combretastatins C Pérez-Melero, ABS Maya, B del Rey, R Peláez, E Caballero, ... Bioorganic & medicinal chemistry letters 14 (14), 3771-3774, 2004 | 104 | 2004 |
| Endowing indole-based tubulin inhibitors with an anchor for derivatization: highly potent 3-substituted indolephenstatins and indoleisocombretastatins R Alvarez, P Puebla, JF Diaz, AC Bento, R Garcia-Navas, ... Journal of medicinal chemistry 56 (7), 2813-2827, 2013 | 81 | 2013 |
| Synthesis and pharmacological activity of diarylindole derivatives. Cytotoxic agents based on combretastatins M Medarde, AC Ramos, E Caballero, RPL Clairac, JL López, ... Bioorganic & medicinal chemistry letters 9 (16), 2303-2308, 1999 | 80 | 1999 |
| Isocombretastatins A: 1, 1-diarylethenes as potent inhibitors of tubulin polymerization and cytotoxic compounds R Álvarez, C Álvarez, F Mollinedo, BG Sierra, M Medarde, R Peláez Bioorganic & medicinal chemistry 17 (17), 6422-6431, 2009 | 71 | 2009 |
| Synthesis and antineoplastic activity of combretastatin analogues: Heterocombretastatins M Medarde, A Ramos, E Caballero, RPL de Clairac, JL López, ... European journal of medicinal chemistry 33 (1), 71-77, 1998 | 59 | 1998 |
| Naphthylphenstatins as tubulin ligands: synthesis and biological evaluation C Álvarez, R Álvarez, P Corchete, C Pérez-Melero, R Peláez, M Medarde Bioorganic & medicinal chemistry 16 (19), 8999-9008, 2008 | 57 | 2008 |
| Diarylmethyloxime and hydrazone derivatives with 5-indolyl moieties as potent inhibitors of tubulin polymerization C Alvarez, R Alvarez, P Corchete, JL López, C Pérez-Melero, R Peláez, ... Bioorganic & medicinal chemistry 16 (11), 5952-5961, 2008 | 54 | 2008 |
| New naphthylcombretastatins. Modifications on the ethylene bridge ABS Maya, C Pérez-Melero, N Salvador, R Peláez, E Caballero, ... Bioorganic & medicinal chemistry 13 (6), 2097-2107, 2005 | 53 | 2005 |
| Exploring the effect of 2, 3, 4-trimethoxy-phenyl moiety as a component of indolephenstatins C Álvarez, R Álvarez, P Corchete, C Pérez-Melero, R Peláez, M Medarde European journal of medicinal chemistry 45 (2), 588-597, 2010 | 52 | 2010 |
| Controlling binding orientation in hairpin polyamide DNA complexes CA Hawkins, RP de Clairac, RN Dominey, EE Baird, S White, PB Dervan, ... Journal of the American Chemical Society 122 (22), 5235-5243, 2000 | 49 | 2000 |
| Pyridine based antitumour compounds acting at the colchicine site R æ# 129; lvarez, L Aramburu, P Puebla, E Caballero, M González, ... Current medicinal chemistry 23 (11), 1100-1130, 2016 | 47 | 2016 |
| Heterolignans AC Ramos, RPL de Clairac, M Medarde Heterocycles: an international journal for reviews and communications in …, 1999 | 47 | 1999 |
| A new approach to the synthesis of podophyllotoxin based on epimerization reactions M Medarde, AC Ramos, E Caballero, JL López, RPL Clairac, ... Tetrahedron letters 37 (15), 2663-2666, 1996 | 44 | 1996 |
| Design, synthesis and cytotoxic activities of naphthyl analogues of combretastatin A-4 ABS Maya, B del Rey, RPL de Clairac, E Caballero, I Barasoain, ... Bioorganic & medicinal chemistry letters 10 (22), 2549-2551, 2000 | 42 | 2000 |
| Heterolignanolides. Furo-and thieno-analogues of podophyllotoxin and thuriferic acid AC Ramos, R Peláez, JL López, E Caballero, M Medarde, ... Tetrahedron 57 (18), 3963-3977, 2001 | 41 | 2001 |
| NMR Characterization of the Aliphatic β/β Pairing for Recognition of A⊙ T/T⊙ A Base Pairs in the Minor Groove of DNA RPL De Clairac, CJ Seel, BH Geierstanger, M Mrksich, EE Baird, ... Journal of the American Chemical Society 121 (13), 2956-2964, 1999 | 41 | 1999 |
| Synthesis and biological activity of naphthalene analogues of phenstatins: Naphthylphenstatins C Álvarez, R Alvarez, P Corchete, C Pérez-Melero, R Peláez, M Medarde Bioorganic & medicinal chemistry letters 17 (12), 3417-3420, 2007 | 40 | 2007 |
| Antitubulin sulfonamides: The successful combination of an established drug class and a multifaceted target A Vicente‐Blázquez, M González, R Álvarez, S Del Mazo, M Medarde, ... Medicinal research reviews 39 (3), 775-830, 2019 | 39 | 2019 |
