Phagocytosis of rod outer segments by retinal pigment epithelial cells requires αvβ5 integrin for binding but not for internalization SC Finnemann, VL Bonilha, AD Marmorstein, E Rodriguez-Boulan Proceedings of the National Academy of Sciences 94 (24), 12932-12937, 1997 | 499 | 1997 |
Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking αvβ5 integrin EF Nandrot, Y Kim, SE Brodie, X Huang, D Sheppard, SC Finnemann The Journal of experimental medicine 200 (12), 1539-1545, 2004 | 369 | 2004 |
The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium SC Finnemann, LW Leung, E Rodriguez-Boulan Proceedings of the National Academy of Sciences 99 (6), 3842-3847, 2002 | 368 | 2002 |
Essential role for MFG-E8 as ligand for αvβ5 integrin in diurnal retinal phagocytosis EF Nandrot, M Anand, D Almeida, K Atabai, D Sheppard, SC Finnemann Proceedings of the National Academy of Sciences 104 (29), 12005-12010, 2007 | 278 | 2007 |
Understanding photoreceptor outer segment phagocytosis: use and utility of RPE cells in culture F Mazzoni, H Safa, SC Finnemann Experimental eye research 126, 51-60, 2014 | 270 | 2014 |
Focal adhesion kinase signaling promotes phagocytosis of integrin‐bound photoreceptors SC Finnemann The EMBO journal, 2003 | 266 | 2003 |
Differential roles of CD36 and αvβ5 integrin in photoreceptor phagocytosis by the retinal pigment epithelium SC Finnemann, RL Silverstein The Journal of experimental medicine 194 (9), 1289-1298, 2001 | 212 | 2001 |
Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for … M Sun, SC Finnemann, M Febbraio, L Shan, SP Annangudi, EA Podrez, ... Journal of Biological Chemistry 281 (7), 4222-4230, 2006 | 203 | 2006 |
Ezrin promotes morphogenesis of apical microvilli and basal infoldings in retinal pigment epithelium VL Bonilha, SC Finnemann, E Rodriguez-Boulan The Journal of cell biology 147 (7), 1533-1548, 1999 | 199 | 1999 |
The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells C Vives-Bauza, M Anand, AK Shirazi, J Magrane, J Gao, ... Journal of Biological Chemistry 283 (36), 24770-24780, 2008 | 189 | 2008 |
The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells A Lakkaraju, SC Finnemann, E Rodriguez-Boulan Proceedings of the National Academy of Sciences 104 (26), 11026-11031, 2007 | 183 | 2007 |
Regulation of phagocytosis by Rho GTPases Y Mao, SC Finnemann Small GTPases 6 (2), 89-99, 2015 | 171 | 2015 |
Macrophage and retinal pigment epithelium phagocytosis: apoptotic cells and photoreceptors compete for αvβ3 and αvβ5 integrins, and protein kinase C regulates αvβ5 binding and … SC Finnemann, E Rodriguez-Boulan The Journal of experimental medicine 190 (6), 861-874, 1999 | 169 | 1999 |
Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5−/− or Mfge8−/− mouse retina L Ruggiero, MP Connor, J Chen, R Langen, SC Finnemann Proceedings of the National Academy of Sciences 109 (21), 8145-8148, 2012 | 165 | 2012 |
Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration TL Lenis, J Hu, SY Ng, Z Jiang, S Sarfare, MB Lloyd, NJ Esposito, ... Proceedings of the National Academy of Sciences 115 (47), E11120-E11127, 2018 | 142 | 2018 |
LI-cadherin–mediated cell–cell adhesion does not require cytoplasmic interactions B Kreft, D Berndorff, A Böttinger, S Finnemann, D Wedlich, M Hortsch, ... The Journal of cell biology 136 (5), 1109, 1997 | 135 | 1997 |
Morphogenesis of the Retinal Pigment Epithelium: Toward Understanding Retinal Degenerative Diseasesa AD Marmorstein, SC Finnemann, VL Bonilha, E RODRIGUEZ‐BOULAN Annals of the New York Academy of Sciences 857 (1), 1-12, 1998 | 120 | 1998 |
Tetraspanin CD81 is required for the αvβ5-integrin-dependent particle-binding step of RPE phagocytosis Y Chang, SC Finnemann Journal of cell science 120 (17), 3053-3063, 2007 | 98 | 2007 |
Novel role for αvβ5-integrin in retinal adhesion and its diurnal peak EF Nandrot, M Anand, M Sircar, SC Finnemann American Journal of Physiology-Cell Physiology 290 (4), C1256-C1262, 2006 | 91 | 2006 |
Mertk Activation During RPE Phagocytosis in Vivo Requires αVβ5 Integrin SC Finnemann, EF Nandrot Retinal degenerative diseases, 499-503, 2006 | 89 | 2006 |