| Molecular signature of CD8+ T cell exhaustion during chronic viral infection EJ Wherry, SJ Ha, SM Kaech, WN Haining, S Sarkar, V Kalia, ... Immunity 27 (4), 670-684, 2007 | 2502 | 2007 |
| Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection HT Jin, AC Anderson, WG Tan, EE West, SJ Ha, K Araki, GJ Freeman, ... Proceedings of the National Academy of Sciences 107 (33), 14733-14738, 2010 | 1038 | 2010 |
| Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8+ T cells B Youngblood, KJ Oestreich, SJ Ha, J Duraiswamy, RS Akondy, EE West, ... Immunity 35 (3), 400-412, 2011 | 471 | 2011 |
| Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination D Masopust, SJ Ha, V Vezys, R Ahmed The Journal of Immunology 177 (2), 831-839, 2006 | 393 | 2006 |
| PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells EE West, HT Jin, AU Rasheed, P Penaloza-MacMaster, SJ Ha, WG Tan, ... The Journal of clinical investigation 123 (6), 2604-2615, 2013 | 354 | 2013 |
| Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases YH Sung, JM Kim, HT Kim, J Lee, J Jeon, Y Jin, JH Choi, YH Ban, SJ Ha, ... Genome research 24 (1), 125-131, 2014 | 338 | 2014 |
| Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection SJ Ha, SN Mueller, EJ Wherry, DL Barber, RD Aubert, AH Sharpe, ... The Journal of experimental medicine 205 (3), 543-555, 2008 | 308 | 2008 |
| PD-L1 expression on immune cells, but not on tumor cells, is a favorable prognostic factor for head and neck cancer patients HR Kim, SJ Ha, MH Hong, SJ Heo, YW Koh, EC Choi, EK Kim, KH Pyo, ... Scientific reports 6 (1), 36956, 2016 | 287 | 2016 |
| IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection DG Brooks, SJ Ha, H Elsaesser, AH Sharpe, GJ Freeman, MBA Oldstone Proceedings of the National Academy of Sciences 105 (51), 20428-20433, 2008 | 274 | 2008 |
| Recruitment of monocytes/macrophages in different tumor microenvironments HW Lee, HJ Choi, SJ Ha, KT Lee, YG Kwon Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1835 (2), 170-179, 2013 | 260 | 2013 |
| Activation of IL-6R/JAK1/STAT3 Signaling Induces De Novo Resistance to Irreversible EGFR Inhibitors in Non–Small Cell Lung Cancer with T790M Resistance … SM Kim, OJ Kwon, YK Hong, JH Kim, F Solca, SJ Ha, RA Soo, ... Molecular cancer therapeutics 11 (10), 2254-2264, 2012 | 236 | 2012 |
| Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection RD Aubert, AO Kamphorst, S Sarkar, V Vezys, SJ Ha, DL Barber, L Ye, ... Proceedings of the National Academy of Sciences 108 (52), 21182-21187, 2011 | 226 | 2011 |
| Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection Q Li, PJ Skinner, SJ Ha, L Duan, TL Mattila, A Hage, C White, DL Barber, ... Science 323 (5922), 1726-1729, 2009 | 224 | 2009 |
| Fibroblast growth factor receptor 1 gene amplification is associated with poor survival and cigarette smoking dosage in patients with resected squamous cell lung cancer HR Kim, DJ Kim, DR Kang, JG Lee, SM Lim, CY Lee, SY Rha, MK Bae, ... Journal of clinical oncology 31 (6), 731-737, 2013 | 208 | 2013 |
| PD-1 upregulated on regulatory T cells during chronic virus infection enhances the suppression of CD8+ T cell immune response via the interaction with PD-L1 expressed on CD8+ T … HJ Park, JS Park, YH Jeong, J Son, YH Ban, BH Lee, L Chen, J Chang, ... The Journal of Immunology 194 (12), 5801-5811, 2015 | 206 | 2015 |
| Distinct clinical features and outcomes in never‐smokers with nonsmall cell lung cancer who harbor EGFR or KRAS mutations or ALK rearrangement HR Kim, HS Shim, JH Chung, YJ Lee, YK Hong, SY Rha, SH Kim, SJ Ha, ... Cancer 118 (3), 729-739, 2012 | 185 | 2012 |
| Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection JN Blattman, EJ Wherry, SJ Ha, RG Van Der Most, R Ahmed Journal of virology 83 (9), 4386-4394, 2009 | 185 | 2009 |
| PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice SN Mueller, VK Vanguri, SJ Ha, EE West, ME Keir, JN Glickman, ... The Journal of clinical investigation 120 (7), 2508-2515, 2010 | 168 | 2010 |
| Genome-wide identification of differentially methylated promoters and enhancers associated with response to anti-PD-1 therapy in non-small cell lung cancer JW Cho, MH Hong, SJ Ha, YJ Kim, BC Cho, I Lee, HR Kim Experimental & molecular medicine 52 (9), 1550-1563, 2020 | 162 | 2020 |
| Single-cell transcriptome analysis reveals TOX as a promoting factor for T cell exhaustion and a predictor for anti-PD-1 responses in human cancer K Kim, S Park, SY Park, G Kim, SM Park, JW Cho, DH Kim, YM Park, ... Genome Medicine 12, 1-16, 2020 | 138 | 2020 |