Individual brain organoids reproducibly form cell diversity of the human cerebral cortex S Velasco, AJ Kedaigle, SK Simmons, A Nash, M Rocha, G Quadrato, ... Nature 570 (7762), 523-527, 2019 | 905 | 2019 |
Autism genes converge on asynchronous development of shared neuron classes B Paulsen, S Velasco, AJ Kedaigle, M Pigoni, G Quadrato, AJ Deo, ... Nature 602 (7896), 268-273, 2022 | 301 | 2022 |
Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient B da Silveira Paulsen, R de Moraes Maciel, A Galina, MS Da Silveira, ... Cell transplantation 21 (7), 1547-1559, 2012 | 168 | 2012 |
Successful scale-up of human embryonic stem cell production in a stirred microcarrier culture system AM Fernandes, PAN Marinho, RC Sartore, BS Paulsen, RM Mariante, ... Brazilian journal of medical and biological research 42, 515-522, 2009 | 144 | 2009 |
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex A Uzquiano, AJ Kedaigle, M Pigoni, B Paulsen, X Adiconis, K Kim, T Faits, ... Cell 185 (20), 3770-3788. e27, 2022 | 140 | 2022 |
Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR–Cas9 genome editing BS Paulsen, PK Mandal, RL Frock, B Boyraz, R Yadav, S Upadhyayula, ... Nature biomedical engineering 1 (11), 878-888, 2017 | 116 | 2017 |
3D brain organoids: studying brain development and disease outside the embryo S Velasco, B Paulsen, P Arlotta Annual review of neuroscience 43 (1), 375-389, 2020 | 94 | 2020 |
Accelerating neuronal aging in in vitro model brain disorders: a focus on reactive oxygen species PB Campos, BS Paulsen, SK Rehen Frontiers in aging neuroscience 6, 292, 2014 | 71 | 2014 |
Co-expression network of neural-differentiation genes shows specific pattern in schizophrenia M Maschietto, AC Tahira, R Puga, L Lima, D Mariani, ... BMC medical genomics 8, 1-15, 2015 | 58 | 2015 |
Valproate reverts zinc and potassium imbalance in schizophrenia-derived reprogrammed cells B da Silveira Paulsen, SC Cardoso, MP Stelling, DV Cadilhe, SK Rehen Schizophrenia research 154 (1-3), 30-35, 2014 | 53 | 2014 |
Generation of iPSC-derived human peripheral sensory neurons releasing substance P elicited by TRPV1 agonists MZP Guimarães, R De Vecchi, G Vitória, JK Sochacki, BS Paulsen, I Lima, ... Frontiers in molecular neuroscience 11, 277, 2018 | 47 | 2018 |
Agathisflavone enhances retinoic acid-induced neurogenesis and its receptors α and β in pluripotent stem cells BS Paulsen, CS Souza, L Chicaybam, MH Bonamino, M Bahia, SL Costa, ... Stem Cells and Development 20 (10), 1711-1721, 2011 | 47 | 2011 |
Xeno-free production of human embryonic stem cells in stirred microcarrier systems using a novel animal/human-component-free medium PAN Marinho, DT Vareschini, IC Gomes, BS Paulsen, DR Furtado, ... Tissue Engineering Part C: Methods 19 (2), 146-155, 2013 | 46 | 2013 |
Retinoic acid-treated pluripotent stem cells undergoing neurogenesis present increased aneuploidy and micronuclei formation RC Sartore, PB Campos, CA Trujillo, BL Ramalho, PD Negraes, ... PloS one 6 (6), e20667, 2011 | 39 | 2011 |
Single-cell multiomics atlas of organoid development uncovers longitudinal molecular programs of cellular diversification of the human cerebral cortex A Uzquiano, AJ Kedaigle, M Pigoni, B Paulsen, X Adiconis, K Kim, T Faits, ... BioRxiv, 2022.03. 17.484798, 2022 | 28 | 2022 |
Commitment of human pluripotent stem cells to a neural lineage is induced by the pro-estrogenic flavonoid apigenin CS Souza, BS Paulsen, S Devalle, S Lima Costa, HL Borges, SK Rehen Advances in Regenerative Biology 2 (1), 29244, 2015 | 24 | 2015 |
Implications of aneuploidy for stem cell biology and brain therapeutics S Devalle, RC Sartore, BS Paulsen, HL Borges, RAP Martins, SK Rehen Frontiers in cellular neuroscience 6, 36, 2012 | 24 | 2012 |
Pluripotent stem cells as a model to study oxygen metabolism in neurogenesis and neurodevelopmental disorders B da Silveira Paulsen, MS da Silveira, A Galina, SK Rehen Archives of biochemistry and biophysics 534 (1-2), 3-10, 2013 | 21 | 2013 |
Generation of iPS cell lines from schizophrenia patients using a non-integrative method J Sochacki, S Devalle, M Reis, R de Moraes Maciel, B da Silveira Paulsen, ... Stem cell research 17 (1), 97-101, 2016 | 20 | 2016 |
How collaboration between bioethicists and neuroscientists can advance research I Hyun, JC Scharf-Deering, S Sullivan, JD Aach, P Arlotta, ML Baum, ... Nature Neuroscience 25 (11), 1399-1401, 2022 | 19 | 2022 |