CRISPR-Cas antimicrobials: Challenges and future prospects E Pursey, D Sünderhauf, WH Gaze, ER Westra, S van Houte PLoS pathogens 14 (6), e1006990, 2018 | 149 | 2018 |
Bacterial biodiversity drives the evolution of CRISPR-based phage resistance EO Alseth, E Pursey, AM Luján, I McLeod, C Rollie, ER Westra Nature 574 (7779), 549-552, 2019 | 135 | 2019 |
CRISPR-Cas is associated with fewer antibiotic resistance genes in bacterial pathogens E Pursey, T Dimitriu, FL Paganelli, ER Westra, S van Houte Philosophical Transactions of the Royal Society B 377 (1842), 20200464, 2022 | 41 | 2022 |
Removal of AMR plasmids using a mobile, broad host-range CRISPR-Cas9 delivery tool D Walker-Sünderhauf, U Klümper, E Pursey, ER Westra, WH Gaze, ... Microbiology 169 (5), 2023 | 11 | 2023 |
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape A Maestri, BJ Pons, E Pursey, CE Chong, S Gandon, R Custodio, A Olina, ... Cell Host & Microbe, 2024 | 5 | 2024 |
Transient eco-evolutionary dynamics early in a phage epidemic have strong and lasting impact on the long-term evolution of bacterial defences BNJ Watson, E Pursey, S Gandon, ER Westra PLoS biology 21 (9), e3002122, 2023 | 5 | 2023 |
Bacterial defences interact synergistically by disrupting phage cooperation A Maestri, E Pursey, C Chong, BJ Pons, S Gandon, R Custodio, ... bioRxiv, 2023.03. 30.534895, 2023 | 4 | 2023 |
Antibiotics of the future are prone to resistance in Gram-negative pathogens L Daruka, MS Czikkely, P Szili, Z Farkas, D Balogh, E Maharramov, TH Vu, ... bioRxiv, 2023.07. 23.550022, 2023 | 3 | 2023 |
Comparative genomics approaches to understand the interplay between bacterial defences and mobile genetic elements E Pursey University of Exeter, 2023 | | 2023 |
Eco-evolutionary feedbacks shape the evolution of constitutive and inducible defences B Watson, E Pursey, S Gandon, ER Westra bioRxiv, 2023.04. 14.536855, 2023 | | 2023 |
Modelling the distribution of antimicrobial resistance genes across geography, climate, host species and phylogroup in 16,000 E. coli genomes E Pursey, T Dimitriu, WH Gaze, ER Westra, S van Houte medRxiv, 2022.08. 05.22278465, 2022 | | 2022 |
CRISPR-Cas is associated with fewer antibiotic resistance genes in bacterial pathogens E Pursey, T Dimitriu, FL Paganelli, ER Westra, S van Houte bioRxiv, 2021 | | 2021 |