The Warburg effect: how does it benefit cancer cells? MV Liberti, JW Locasale Trends in biochemical sciences 41 (3), 211-218, 2016 | 5097 | 2016 |
Distinct regulation of Th17 and Th1 cell differentiation by glutaminase-dependent metabolism MO Johnson, MM Wolf, MZ Madden, G Andrejeva, A Sugiura, ... Cell 175 (7), 1780-1795. e19, 2018 | 611 | 2018 |
A predictive model for selective targeting of the Warburg effect through GAPDH inhibition with a natural product MV Liberti, Z Dai, SE Wardell, JA Baccile, X Liu, X Gao, R Baldi, ... Cell metabolism 26 (4), 648-659. e8, 2017 | 211 | 2017 |
Serine synthesis through PHGDH coordinates nucleotide levels by maintaining central carbon metabolism MA Reid, AE Allen, S Liu, MV Liberti, P Liu, X Liu, Z Dai, X Gao, Q Wang, ... Nature communications 9 (1), 5442, 2018 | 198 | 2018 |
Rational design of selective allosteric inhibitors of PHGDH and serine synthesis with anti-tumor activity Q Wang, MV Liberti, P Liu, X Deng, Y Liu, JW Locasale, L Lai Cell chemical biology 24 (1), 55-65, 2017 | 140 | 2017 |
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence KR Singleton, L Crawford, E Tsui, HE Manchester, O Maertens, X Liu, ... Cell reports 21 (10), 2796-2812, 2017 | 106 | 2017 |
Histone lactylation: a new role for glucose metabolism MV Liberti, JW Locasale Trends in biochemical sciences 45 (3), 179-182, 2020 | 103 | 2020 |
PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis N Yamaguchi, EM Weinberg, A Nguyen, MV Liberti, H Goodarzi, ... Elife 8, e52135, 2019 | 83 | 2019 |
Leucyl-tRNA synthetase is a tumour suppressor in breast cancer and regulates codon-dependent translation dynamics MC Passarelli, AM Pinzaru, H Asgharian, MV Liberti, S Heissel, H Molina, ... Nature cell biology 24 (3), 307-315, 2022 | 44 | 2022 |
Discovery of a potent GLUT inhibitor from a library of rapafucins by using 3D microarrays Z Guo, Z Cheng, J Wang, W Liu, H Peng, Y Wang, AVS Rao, R Li, X Ying, ... Angewandte Chemie 131 (48), 17318-17322, 2019 | 35 | 2019 |
RRmix: A method for simultaneous batch effect correction and analysis of metabolomics data in the absence of internal standards S Salerno Jr, M Mehrmohamadi, MV Liberti, M Wan, MT Wells, JG Booth, ... PloS one 12 (6), e0179530, 2017 | 25 | 2017 |
The TGF-β/HDAC7 axis suppresses TCA cycle metabolism in renal cancer H Nam, A Kundu, S Karki, GJ Brinkley, DS Chandrashekar, RL Kirkman, ... JCI insight 6 (22), 2021 | 21 | 2021 |
Evolved resistance to partial GAPDH inhibition results in loss of the Warburg effect and in a different state of glycolysis MV Liberti, AE Allen, V Ramesh, Z Dai, KR Singleton, Z Guo, JO Liu, ... Journal of Biological Chemistry 295 (1), 111-124, 2020 | 18 | 2020 |
A new layer of glycolysis MV Liberti, JW Locasale Nature Chemical Biology 12 (8), 577-578, 2016 | 17 | 2016 |
Arginine limitation drives a directed codon-dependent DNA sequence evolution response in colorectal cancer cells DJ Hsu, J Gao, N Yamaguchi, A Pinzaru, Q Wu, N Mandayam, M Liberti, ... Science Advances 9 (1), eade9120, 2023 | 14 | 2023 |
The Na+/K+ ATPase Regulates Glycolysis and Defines Immunometabolism in Tumors SM Sanderson, Z Xiao, AJ Wisdom, S Bose, MV Liberti, MA Reid, E Hocke, ... bioRxiv, 2020.03. 31.018739, 2020 | 9 | 2020 |
TGF-β signaling suppresses TCA cycle metabolism in renal cancer H Nam, A Kundu, S Karki, G Brinkley, DS Chandrashekar, RL Kirkman, ... bioRxiv, 2021.02. 19.429599, 2021 | 3 | 2021 |
A link between metabolic energetics and pancreatic cancer mechanosensing MV Liberti, K Birsoy Nature Metabolism 2 (1), 5-6, 2020 | 2 | 2020 |
PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic pyrimidine nucleotide biosynthesis N Yamaguchi, EM Weinberg, A Nguyen, MV Liberti, H Goodarzi, ... bioRxiv, 833186, 2019 | 1 | 2019 |
Evolved resistance to GAPDH inhibition results in loss of the Warburg Effect but retains a different state of glycolysis MV Liberti, AE Allen, V Ramesh, Z Dai, KR Singleton, Z Guo, JO Liu, ... bioRxiv, 602557, 2019 | 1 | 2019 |