Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor YM Kerdiles, DR Beisner, R Tinoco, AS Dejean, DH Castrillon, ... Nature immunology 10 (2), 176-184, 2009 | 632 | 2009 |
Cell-intrinsic transforming growth factor-β signaling mediates virus-specific CD8+ T cell deletion and viral persistence in vivo R Tinoco, V Alcalde, Y Yang, K Sauer, EI Zuniga Immunity 31 (1), 145-157, 2009 | 329 | 2009 |
PSGL-1 is an immune checkpoint regulator that promotes T cell exhaustion R Tinoco, F Carrette, ML Barraza, DC Otero, J Magaña, MW Bosenberg, ... Immunity 44 (5), 1190-1203, 2016 | 196 | 2016 |
Regulation of antigen-experienced T cells: lessons from the quintessential memory marker CD44 BJG Baaten, R Tinoco, AT Chen, LM Bradley Frontiers in immunology 3, 23, 2012 | 182 | 2012 |
PSGL-1: a new player in the immune checkpoint landscape R Tinoco, DC Otero, AA Takahashi, LM Bradley Trends in immunology 38 (5), 323-335, 2017 | 151 | 2017 |
Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice Y Li, R Tinoco, L Elmén, I Segota, Y Xian, Y Fujita, A Sahu, R Zarecki, ... Nature communications 10 (1), 1492, 2019 | 150 | 2019 |
Prebiotic-induced anti-tumor immunity attenuates tumor growth Y Li, L Elmén, I Segota, Y Xian, R Tinoco, Y Feng, Y Fujita, RRS Muñoz, ... Cell reports 30 (6), 1753-1766. e6, 2020 | 135 | 2020 |
Regulation of S100A8 stability by RNF5 in intestinal epithelial cells determines intestinal inflammation and severity of colitis YU Fujita, A Khateb, Y Li, R Tinoco, T Zhang, H Bar-Yoseph, MA Tam, ... Cell reports 24 (12), 3296-3311. e6, 2018 | 60 | 2018 |
Ubiquitin ligases in cancer immunotherapy–balancing antitumor and autoimmunity Y Fujita, R Tinoco, Y Li, D Senft, AR Ze’ev Trends in molecular medicine 25 (5), 428-443, 2019 | 49 | 2019 |
PSGL-1 Immune Checkpoint Inhibition for CD4+ T Cell Cancer Immunotherapy JM DeRogatis, KM Viramontes, EN Neubert, R Tinoco Frontiers in Immunology 12, 636238, 2021 | 44 | 2021 |
Nuclear pore complex-mediated modulation of TCR signaling is required for naïve CD4+ T cell homeostasis J Borlido, S Sakuma, M Raices, F Carrette, R Tinoco, LM Bradley, ... Nature immunology 19 (6), 594-605, 2018 | 35 | 2018 |
Targeting the PSGL-1 Immune Checkpoint Promotes Immunity to PD-1–Resistant Melanoma JM DeRogatis, KM Viramontes, EN Neubert, ML Henriquez, ... Cancer immunology research 10 (5), 612-625, 2022 | 28 | 2022 |
Siah2 control of T-regulatory cells limits anti-tumor immunity M Scortegagna, K Hockemeyer, I Dolgalev, J Poźniak, F Rambow, Y Li, ... Nature communications 11 (1), 99, 2020 | 26 | 2020 |
PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion JL Hope, DC Otero, EA Bae, CJ Stairiker, AB Palete, HA Faso, M Lin, ... Cell reports 42 (5), 2023 | 20 | 2023 |
PSGL-1 is a T cell intrinsic inhibitor that regulates effector and memory differentiation and responses during viral infection R Tinoco, EN Neubert, CJ Stairiker, ML Henriquez, LM Bradley Frontiers in Immunology 12, 677824, 2021 | 20 | 2021 |
HMGB2 regulates the differentiation and stemness of exhausted CD8+ T cells during chronic viral infection and cancer EN Neubert, JM DeRogatis, SA Lewis, KM Viramontes, P Ortega, ... Nature Communications 14 (1), 5631, 2023 | 19 | 2023 |
Cell-Intrinsic CD38 Expression Sustains Exhausted CD8+ T Cells by Regulating Their Survival and Metabolism during Chronic Viral Infection JM DeRogatis, EN Neubert, KM Viramontes, ML Henriquez, DA Nicholas, ... Journal of Virology 97 (4), e00225-23, 2023 | 13 | 2023 |
PD-1 immune checkpoint blockade and PSGL-1 inhibition synergize to reinvigorate exhausted T cells KM Viramontes, EN Neubert, JM DeRogatis, R Tinoco Frontiers in Immunology 13, 869768, 2022 | 13 | 2022 |
The cure from within? a review of the microbiome and diet in melanoma P Kumar, D Brazel, J DeRogatis, JBG Valerin, K Whiteson, WA Chow, ... Cancer and Metastasis Reviews 41 (2), 261-280, 2022 | 12 | 2022 |
Targeting the PSGL-1 pathway for immune modulation R Tinoco, LM Bradley Immunotherapy 9 (10), 785-788, 2017 | 10 | 2017 |