Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis K Wouters, PJ van Gorp, V Bieghs, MJ Gijbels, H Duimel, D Lütjohann, ... Hepatology 48 (2), 474-486, 2008 | 580 | 2008 |
Roles of PPARs in NAFLD: potential therapeutic targets A Tailleux, K Wouters, B Staels Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2012 | 338 | 2012 |
Macrophage microRNA-155 promotes cardiac hypertrophy and failure S Heymans, MF Corsten, W Verhesen, P Carai, REW Van Leeuwen, ... Circulation 128 (13), 1420-1432, 2013 | 292 | 2013 |
Abdominal subcutaneous and visceral adipocyte size, lipolysis and inflammation relate to insulin resistance in male obese humans K Verboven, K Wouters, K Gaens, D Hansen, M Bijnen, S Wetzels, ... Scientific reports 8 (1), 4677, 2018 | 265 | 2018 |
Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype NMJ Hanssen, K Wouters, MS Huijberts, MJ Gijbels, JC Sluimer, ... European heart journal 35 (17), 1137-1146, 2014 | 226 | 2014 |
Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates R Shiri-Sverdlov, K Wouters, PJ van Gorp, MJ Gijbels, B Noel, L Buffat, ... Journal of hepatology 44 (4), 732-741, 2006 | 224 | 2006 |
LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease V Bieghs, PJ Van Gorp, K Wouters, T Hendrikx, MJ Gijbels, M van Bilsen, ... PloS one 7 (1), e30668, 2012 | 211 | 2012 |
Understanding hyperlipidemia and atherosclerosis: lessons from genetically modified apoe and ldlr mice K Wouters, R Shiri-Sverdlov, PJ van Gorp, M van Bilsen, MH Hofker Clinical Chemistry and Laboratory Medicine (CCLM) 43 (5), 470-479, 2005 | 207 | 2005 |
Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice V Bieghs, K Wouters, PJ Van Gorp, MJJ Gijbels, MPJ De Winther, ... Gastroenterology 138 (7), 2477-2486. e3, 2010 | 191 | 2010 |
Functional genomics of the CDKN2A/B locus in cardiovascular and metabolic disease: what have we learned from GWASs? SA Hannou, K Wouters, R Paumelle, B Staels Trends in Endocrinology & Metabolism 26 (4), 176-184, 2015 | 167 | 2015 |
Plant-based sterols and stanols in health & disease:“Consequences of human development in a plant-based environment?” J Plat, S Baumgartner, T Vanmierlo, D Lütjohann, KL Calkins, DG Burrin, ... Progress in lipid research 74, 87-102, 2019 | 159 | 2019 |
Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice M Bijnen, T Josefs, I Cuijpers, CJ Maalsen, J van de Gaar, M Vroomen, ... Gut 67 (7), 1317-1327, 2018 | 140 | 2018 |
Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells V Bieghs, F Verheyen, PJ van Gorp, T Hendrikx, K Wouters, D Lütjohann, ... PloS one 7 (3), e34378, 2012 | 138 | 2012 |
p16INK4a deficiency promotes IL-4–induced polarization and inhibits proinflammatory signaling in macrophages C Cudejko, K Wouters, L Fuentes, SA Hannou, C Paquet, K Bantubungi, ... Blood, The Journal of the American Society of Hematology 118 (9), 2556-2566, 2011 | 127 | 2011 |
Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice K Wouters, M van Bilsen, PJ van Gorp, V Bieghs, D Lütjohann, A Kerksiek, ... FEBS letters 584 (5), 1001-1005, 2010 | 124 | 2010 |
Circulating classical monocytes are associated with CD11c+ macrophages in human visceral adipose tissue K Wouters, K Gaens, M Bijnen, K Verboven, J Jocken, S Wetzels, ... Scientific Reports 7 (1), 42665, 2017 | 102 | 2017 |
Methylglyoxal-derived advanced glycation endproducts in multiple sclerosis S Wetzels, K Wouters, CG Schalkwijk, T Vanmierlo, JJA Hendriks International journal of molecular sciences 18 (2), 421, 2017 | 88 | 2017 |
Human adipose tissue macrophages display activation of cancer-related pathways TH Mayi, M Daoudi, B Derudas, B Gross, G Bories, K Wouters, J Brozek, ... Journal of Biological Chemistry 287 (26), 21904-21913, 2012 | 86 | 2012 |
Peroxisome proliferator–activated receptor-α gene level differently affects lipid metabolism and inflammation in apolipoprotein E2 knock-in mice F Lalloyer, K Wouters, M Baron, S Caron, E Vallez, J Vanhoutte, E Baugé, ... Arteriosclerosis, thrombosis, and vascular biology 31 (7), 1573-1579, 2011 | 80 | 2011 |
Delayed intervention with Pyridoxamine improves metabolic function and prevents adipose tissue inflammation and insulin resistance in high-fat diet–induced obese mice DE Maessen, O Brouwers, KH Gaens, K Wouters, JP Cleutjens, ... Diabetes 65 (4), 956-966, 2016 | 79 | 2016 |