Richard T Eastman

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David FidockProfessor of Microbiology & Immunology and of Medical Sciences (in Medicine), Columbia UniversityBestätigte E-Mail-Adresse bei columbia.edu
Christophe LMJ VerlindeAssociate professor of Biochemistry, University of Washington, SeattleBestätigte E-Mail-Adresse bei u.washington.edu
Sittiporn PattaradilokratAssistant Professor, Faculty of Science, Chulalongkorn UniversityBestätigte E-Mail-Adresse bei Chula.ac.th
Martine ZilversmitSackler Institute of Comparative Genomics at the American Museum of Natural HistoryBestätigte E-Mail-Adresse bei amnh.org
Elizabeth A. WinzelerProfessor, University of California San DiegoBestätigte E-Mail-Adresse bei ucsd.edu
Geoffrey Chi-JohnstonCruiseBestätigte E-Mail-Adresse bei getcruise.com
Deborah SmithUniversity of YorkBestätigte E-Mail-Adresse bei york.ac.uk
Manuel LlinásDistinguished Professor of Biochemistry & Molecular Biology, The Pennsylvania State UniversityBestätigte E-Mail-Adresse bei psu.edu
Anbu Karani AdikesavanUTHealth McGovern Medical School (Houston, Texas)Bestätigte E-Mail-Adresse bei uth.tmc.edu
Andreas Martin LisewskiConstructor University (formerly Jacobs University) BremenBestätigte E-Mail-Adresse bei constructor.university
Olivier LichtargeProfessor of Molecular and Human Genetics, Baylor College of MedicineBestätigte E-Mail-Adresse bei bcm.edu
Seiichi P. T. MatsudaRice University Department of Chemistry and Department of BioSciencesBestätigte E-Mail-Adresse bei rice.edu
Olivo MiottoAssociate Professor, University of OxfordBestätigte E-Mail-Adresse bei tropmedres.ac
Kayode K. OjoUniversity of WashingtonBestätigte E-Mail-Adresse bei u.washington.edu
Kasey RivasResearch Scientist, University of WashingtonBestätigte E-Mail-Adresse bei uw.edu
Debopam ChakrabartiProfessor of Biomedical sciences, University of Central FloridaBestätigte E-Mail-Adresse bei ucf.edu
jerome clainParis Descartes UniversityBestätigte E-Mail-Adresse bei parisdescartes.fr
Peter J MylerUniversity of WashingtonBestätigte E-Mail-Adresse bei seattlechildrens.org
Thomas D. OttoUniversity of GlasgowBestätigte E-Mail-Adresse bei glasgow.ac.uk
Prof. Matthew BerrimanSchool of Infection and Immunity, University of GlasgowBestätigte E-Mail-Adresse bei glasgow.ac.uk

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Richard T Eastman

Novartis Institutes for BioMedical Research- Global Health

Bestätigte E-Mail-Adresse bei novartis.com

Chemical Biology Parasitology Virology Infectious Diseases


Titel Nach Zitationen sortieren Nach Jahr sortieren Nach Titel sortieren	Zitiert von Zitiert von	Jahr
Remdesivir: a review of its discovery and development leading to emergency use authorization for treatment of COVID-19 RT Eastman, JS Roth, KR Brimacombe, A Simeonov, M Shen, S Patnaik, ... ACS central Science 6 (5), 672-683, 2020	1029	2020
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria RT Eastman, DA Fidock Nature Reviews Microbiology 7 (12), 864-874, 2009	711	2009
Drug-resistant malaria: molecular mechanisms and implications for public health I Petersen, R Eastman, M Lanzer FEBS letters 585 (11), 1551-1562, 2011	410	2011
Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue SH Adjalley, GL Johnston, T Li, RT Eastman, EH Ekland, AG Eappen, ... Proceedings of the National Academy of Sciences 108 (47), E1214-E1223, 2011	350	2011
Protein farnesyl and N-myristoyl transferases: piggy-back medicinal chemistry targets for the development of antitrypanosomatid and antimalarial therapeutics MH Gelb, WC Van Voorhis, FS Buckner, K Yokoyama, R Eastman, ... Molecular and biochemical parasitology 126 (2), 155-163, 2003	182	2003
Piperaquine Resistance Is Associated with a Copy Number Variation on Chromosome 5 in Drug-Pressured Plasmodium falciparum Parasites RT Eastman, NV Dharia, EA Winzeler, DA Fidock Antimicrobial agents and chemotherapy 55 (8), 3908-3916, 2011	165	2011
Thematic review series: lipid posttranslational modifications. Fighting parasitic disease by blocking protein farnesylation RT Eastman, FS Buckner, K Yokoyama, MH Gelb, WC Van Voorhis Journal of lipid research 47 (2), 233-240, 2006	156	2006
Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate AM Lisewski, JP Quiros, CL Ng, AK Adikesavan, K Miura, N Putluri, ... Cell 158 (4), 916-928, 2014	152	2014
Deep learning identifies synergistic drug combinations for treating COVID-19 W Jin, JM Stokes, RT Eastman, Z Itkin, AV Zakharov, JJ Collins, ... Proceedings of the National Academy of Sciences 118 (39), e2105070118, 2021	149	2021
Recent highlights in antimalarial drug resistance and chemotherapy research DA Fidock, RT Eastman, SA Ward, SR Meshnick Trends in parasitology 24 (12), 537-544, 2008	142	2008
High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations BT Mott, RT Eastman, R Guha, KS Sherlach, A Siriwardana, P Shinn, ... Scientific reports 5 (1), 13891, 2015	123	2015
A Specific Inhibitor of PfCDPK4 Blocks Malaria Transmission: Chemical-genetic Validation KK Ojo, RT Eastman, RSR Vidadala, Z Zhang, KL Rivas, R Choi, JD Lutz, ... The Journal of infectious diseases 209 (2), 275-284, 2014	104	2014
Synergistic and antagonistic drug combinations against SARS-CoV-2 T Bobrowski, L Chen, RT Eastman, Z Itkin, P Shinn, CZ Chen, H Guo, ... Molecular Therapy 29 (2), 873-885, 2021	102	2021
Trypanosoma cruzi Inactivation in Human Platelet Concentrates and Plasma by a Psoralen (Amotosalen HCl) and Long-Wavelength UV WC Van Voorhis, LK Barrett, RT Eastman, R Alfonso, K Dupuis Antimicrobial agents and chemotherapy 47 (2), 475-479, 2003	97	2003
The Candida albicans Lanosterol 14-α-Demethylase (ERG11) Gene Promoter Is Maximally Induced after Prolonged Growth with Antifungal Drugs JL Song, JB Harry, RT Eastman, BG Oliver, TC White Antimicrobial agents and chemotherapy 48 (4), 1136-1144, 2004	94	2004
Drug repurposing screen for compounds inhibiting the cytopathic effect of SARS-CoV-2 CZ Chen, P Shinn, Z Itkin, RT Eastman, R Bostwick, L Rasmussen, ... Frontiers in Pharmacology 11, 592737, 2021	92	2021
Resistance to a protein farnesyltransferase inhibitor in Plasmodium falciparum RT Eastman, J White, O Hucke, K Bauer, K Yokoyama, L Nallan, ... Journal of Biological Chemistry 280 (14), 13554-13559, 2005	90	2005
Targeting ACE2–RBD interaction as a platform for COVID-19 therapeutics: development and drug-repurposing screen of an AlphaLISA proximity assay QM Hanson, KM Wilson, M Shen, Z Itkin, RT Eastman, P Shinn, MD Hall ACS Pharmacology & Translational Science 3 (6), 1352-1360, 2020	82	2020
An OpenData portal to share COVID-19 drug repurposing data in real time KR Brimacombe, T Zhao, RT Eastman, X Hu, K Wang, M Backus, ... BioRxiv, 2020	82	2020
Design and synthesis of peptidomimetic protein farnesyltransferase inhibitors as anti-Trypanosoma brucei agents J Ohkanda, FS Buckner, JW Lockman, K Yokoyama, D Carrico, ... Journal of medicinal chemistry 47 (2), 432-445, 2004	73	2004

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