Large-scale lipidomics identifies associations between plasma sphingolipids and T2DM incidence WS Chew, F Torta, S Ji, H Choi, H Begum, X Sim, CM Khoo, EYH Khoo, ... JCI insight 4 (13), 2019 | 133 | 2019 |
To fingolimod and beyond: The rich pipeline of drug candidates that target S1P signaling WS Chew, W Wang, DR Herr Pharmacological research 113, 521-532, 2016 | 68 | 2016 |
Pleotropic roles of autotaxin in the nervous system present opportunities for the development of novel therapeutics for neurological diseases DR Herr, WS Chew, RL Satish, WY Ong Molecular neurobiology 57 (1), 372-392, 2020 | 48 | 2020 |
Activation of sphingosine 1-phosphate receptor 2 attenuates chemotherapy-induced neuropathy W Wang, P Xiang, WS Chew, F Torta, A Bandla, V Lopez, WL Seow, ... Journal of Biological Chemistry 295 (4), 1143-1152, 2020 | 38 | 2020 |
Immunomodulatory sphingosine-1-phosphates as plasma biomarkers of Alzheimer’s disease and vascular cognitive impairment XY Chua, YL Chai, WS Chew, JR Chong, HL Ang, P Xiang, K Camara, ... Alzheimer's Research & Therapy 12, 1-12, 2020 | 33 | 2020 |
Plasma sphingolipids and risk of cardiovascular diseases: a large-scale lipidomic analysis JYH Seah, WS Chew, F Torta, CM Khoo, MR Wenk, DR Herr, H Choi, ... Metabolomics 16, 1-12, 2020 | 32 | 2020 |
Enriched expression of neutral sphingomyelinase 2 in the striatum is essential for regulation of lipid raft content and motor coordination LHR Tan, AJR Tan, YY Ng, JJE Chua, WS Chew, S Muralidharan, F Torta, ... Molecular neurobiology 55, 5741-5756, 2018 | 31 | 2018 |
Sphingosine 1-phosphate receptor 2 induces otoprotective responses to cisplatin treatment W Wang, MK Shanmugam, P Xiang, TYA Yam, V Kumar, WS Chew, ... Cancers 12 (1), 211, 2020 | 28 | 2020 |
Biological effects of naturally occurring sphingolipids, uncommon variants, and their analogs MKP Lai, WS Chew, F Torta, A Rao, GL Harris, J Chun, DR Herr Neuromolecular medicine 18, 396-414, 2016 | 28 | 2016 |
Short-and long-term changes in blood miRNA levels after nanogold injection in rats—potential biomarkers of nanoparticle exposure WS Chew, KW Poh, NJ Siddiqi, AS Alhomida, LE Yu, WY Ong Biomarkers 17 (8), 750-757, 2012 | 27 | 2012 |
Associations with metabolites in Chinese suggest new metabolic roles in Alzheimer’s and Parkinson’s diseases JF Chai, S Raichur, IW Khor, F Torta, WS Chew, DR Herr, J Ching, ... Human Molecular Genetics 29 (2), 189-201, 2020 | 25 | 2020 |
Lysophosphatidic acid and its receptor LPA1 mediate carrageenan induced inflammatory pain in mice M Srikanth, WS Chew, T Hind, SM Lim, NWJ Hay, JHM Lee, R Rivera, ... European journal of pharmacology 841, 49-56, 2018 | 22 | 2018 |
Dietary fat and protein intake in relation to plasma sphingolipids as determined by a large-scale lipidomic analysis JYH Seah, WS Chew, F Torta, CM Khoo, MR Wenk, DR Herr, ES Tai, ... Metabolites 11 (2), 93, 2021 | 20 | 2021 |
The S1P2 receptor regulates blood-brain barrier integrity and leukocyte extravasation with implications for neurodegenerative disease P Xiang, WS Chew, WL Seow, BWS Lam, WY Ong, DR Herr Neurochemistry International 146, 105018, 2021 | 19 | 2021 |
MRMkit: automated data processing for large-scale targeted metabolomics analysis G Teo, WS Chew, BJ Burla, D Herr, ES Tai, MR Wenk, F Torta, H Choi Analytical Chemistry 92 (20), 13677-13682, 2020 | 16 | 2020 |
Sphingolipidomics analysis of large clinical cohorts. Part 1: technical notes and practical considerations WS Chew, WL Seow, JR Chong, MKP Lai, F Torta, MR Wenk, DR Herr Biochemical and biophysical research communications 504 (3), 596-601, 2018 | 12 | 2018 |
Sphingolipidomics analysis of large clinical cohorts. Part 2: Potential impact and applications JR Chong, P Xiang, W Wang, T Hind, WS Chew, WY Ong, MKP Lai, ... Biochemical and biophysical research communications 504 (3), 602-607, 2018 | 11 | 2018 |
Role of constitutive calcium-independent phospholipase A2 beta in hippocampo-prefrontal cortical long term potentiation and spatial working memory SM Shalini, WS Chew, R Rajkumar, GS Dawe, WY Ong Neurochemistry international 78, 96-104, 2014 | 11 | 2014 |
Preclinical and clinical evidence for the involvement of Sphingosine 1-phosphate signaling in the pathophysiology of vascular cognitive impairment XY Chua, LTY Ho, P Xiang, WS Chew, BWS Lam, CP Chen, WY Ong, ... NeuroMolecular Medicine 23, 47-67, 2021 | 8 | 2021 |
Regulation of Calcium-Independent Phospholipase A2 Expression by Adrenoceptors and Sterol Regulatory Element Binding Protein—Potential Crosstalk Between … WS Chew, WY Ong Molecular neurobiology 53, 500-517, 2016 | 8 | 2016 |