Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours A Mansurov, J Ishihara, P Hosseinchi, L Potin, TM Marchell, A Ishihara, ... Nature biomedical engineering 4 (5), 531-543, 2020 | 192 | 2020 |
Targeted antibody and cytokine cancer immunotherapies through collagen affinity J Ishihara, A Ishihara, K Sasaki, SSY Lee, JM Williford, M Yasui, H Abe, ... Science translational medicine 11 (487), eaau3259, 2019 | 173 | 2019 |
Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy JM Williford, J Ishihara, A Ishihara, A Mansurov, P Hosseinchi, ... Science advances 5 (12), eaay1357, 2019 | 123 | 2019 |
Engineered collagen-binding serum albumin as a drug conjugate carrier for cancer therapy K Sasaki, J Ishihara, A Ishihara, R Miura, A Mansurov, K Fukunaga, ... Science advances 5 (8), eaaw6081, 2019 | 84 | 2019 |
Bacterial adhesion to ultrafiltration membranes: role of hydrophilicity, natural organic matter, and cell-surface macromolecules S BinAhmed, A Hasane, Z Wang, A Mansurov, ... Environmental science & technology 52 (1), 162-172, 2018 | 79 | 2018 |
Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies K Katsumata, J Ishihara, A Mansurov, A Ishihara, MM Raczy, E Yuba, ... Science advances 5 (11), eaay1971, 2019 | 61 | 2019 |
Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker A Mansurov, P Hosseinchi, K Chang, AL Lauterbach, LT Gray, AT Alpar, ... Nature biomedical engineering 6 (7), 819-829, 2022 | 59 | 2022 |
Prolonged residence of an albumin–IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis A Ishihara, J Ishihara, EA Watkins, AC Tremain, M Nguyen, A Solanki, ... Nature Biomedical Engineering 5 (5), 387-398, 2021 | 38 | 2021 |
Polymersomes decorated with the SARS-CoV-2 spike protein receptor-binding domain elicit robust humoral and cellular immunity LR Volpatti, RP Wallace, S Cao, MM Raczy, R Wang, LT Gray, AT Alpar, ... ACS central science 7 (8), 1368-1380, 2021 | 37 | 2021 |
Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant LT Gray, MM Raczy, PS Briquez, TM Marchell, AT Alpar, RP Wallace, ... Biomaterials 278, 121159, 2021 | 29 | 2021 |
Suppression of rheumatoid arthritis by enhanced lymph node trafficking of engineered interleukin‐10 in murine models E Yuba, E Budina, K Katsumata, A Ishihara, A Mansurov, AT Alpar, ... Arthritis & Rheumatology 73 (5), 769-778, 2021 | 27 | 2021 |
Immunoengineering approaches for cytokine therapy A Mansurov, A Lauterbach, E Budina, AT Alpar, JA Hubbell, J Ishihara American Journal of Physiology-Cell Physiology 321 (2), C369-C383, 2021 | 25 | 2021 |
Tumor cell-surface binding of immune stimulating polymeric glyco-adjuvant via cysteine-reactive pyridyl disulfide promotes antitumor immunity AJ Slezak, A Mansurov, MM Raczy, K Chang, AT Alpar, AL Lauterbach, ... ACS Central Science 8 (10), 1435-1446, 2022 | 19 | 2022 |
Therapeutic synthetic and natural materials for immunoengineering A Slezak, K Chang, S Hossainy, A Mansurov, SJ Rowan, JA Hubbell, ... Chemical Society Reviews 53 (4), 1789-1822, 2024 | 10 | 2024 |
Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity S Kang, A Mansurov, T Kurtanich, HR Chun, AJ Slezak, LR Volpatti, ... Science Advances 9 (48), eadh9879, 2023 | 7 | 2023 |
Topically-applied collagen-binding serum albumin-fused interleukin-4 modulates wound microenvironment in non-healing wounds AL Lauterbach, RP Wallace, AT Alpar, KC Refvik, JW Reda, A Ishihara, ... NPJ Regenerative Medicine 8 (1), 49, 2023 | 6 | 2023 |
Prolonged residence of an albumin-IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis (Oct, 10.1038/s41551-020-00627-3, 2020) A Ishihara, J Ishihara, EA Watkins, AC Tremain, M Nguyen, A Solanki, ... NATURE BIOMEDICAL ENGINEERING 4 (11), 1117-1117, 2020 | 2 | 2020 |
Methods and compositions for treating inflammatory and autoimmune conditions with ecm-affinity peptides linked to anti-inflammatory agents JA Hubbell, K Katsumata, A Ishihara, J Ishihara, A Mansurov | 2 | 2020 |
Enhanced lymph node trafficking of engineered IL‐10 suppresses rheumatoid arthritis in murine models E Yuba, E Budina, K Katsumata, A Ishihara, A Mansurov, AT Alpar, ... Arthritis & Rheumatology 73, 769-778, 2020 | 2 | 2020 |
Cysteine-binding adjuvant enhances survival and promotes immune function in a murine model of acute myeloid leukemia AJ Slezak, K Chang, TN Beckman, KC Refvik, AT Alpar, AL Lauterbach, ... Blood advances 8 (7), 1747-1759, 2024 | 1 | 2024 |