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John A. Morris
John A. Morris
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα utoronto.ca - Αρχική σελίδα
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An atlas of genetic influences on osteoporosis in humans and mice
JA Morris, JP Kemp, SE Youlten, L Laurent, JG Logan, RC Chai, ...
Nature genetics 51 (2), 258-266, 2019
7262019
Genetic drivers of epigenetic and transcriptional variation in human immune cells
L Chen, B Ge, FP Casale, L Vasquez, T Kwan, D Garrido-Martín, S Watt, ...
Cell 167 (5), 1398-1414. e24, 2016
7112016
Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis
JP Kemp, JA Morris, C Medina-Gomez, V Forgetta, NM Warrington, ...
Nature genetics 49 (10), 1468-1475, 2017
4652017
Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study
K Trajanoska, JA Morris, L Oei, HF Zheng, DM Evans, DP Kiel, C Ohlsson, ...
bmj 362, 2018
269*2018
Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness
SM Willems, DJ Wright, FR Day, K Trajanoska, PK Joshi, JA Morris, ...
Nature communications 8 (1), 16015, 2017
1972017
A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease
OS Ahmad, JA Morris, M Mujammami, V Forgetta, A Leong, R Li, ...
Nature communications 6 (1), 7060, 2015
1442015
Genetically decreased vitamin D and risk of Alzheimer disease
LE Mokry, S Ross, JA Morris, D Manousaki, V Forgetta, JB Richards
Neurology 87 (24), 2567-2574, 2016
1352016
Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens
JA Morris, C Caragine, Z Daniloski, J Domingo, T Barry, L Lu, K Davis, ...
Science 380 (6646), eadh7699, 2023
118*2023
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease
SE Youlten, JP Kemp, JG Logan, EJ Ghirardello, CM Sergio, MRG Dack, ...
Nature communications 12 (1), 2444, 2021
992021
Development of a polygenic risk score to improve screening for fracture risk: a genetic risk prediction study
V Forgetta, J Keller-Baruch, M Forest, A Durand, S Bhatnagar, JP Kemp, ...
PLoS medicine 17 (7), e1003152, 2020
86*2020
Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps
V Iotchkova, J Huang, JA Morris, D Jain, C Barbieri, K Walter, JL Min, ...
Nature genetics 48 (11), 1303-1312, 2016
802016
A Mendelian randomization study of the effect of type‐2 diabetes and glycemic traits on bone mineral density
OS Ahmad, A Leong, JA Miller, JA Morris, V Forgetta, M Mujammami, ...
Journal of Bone and Mineral Research 32 (5), 1072-1081, 2017
682017
Epigenome‐wide association of DNA methylation in whole blood with bone mineral density
JA Morris, PC Tsai, R Joehanes, J Zheng, K Trajanoska, M Soerensen, ...
Journal of Bone and Mineral Research 32 (8), 1644-1650, 2017
632017
Metabolomic pathways to osteoporosis in middle‐aged women: a genome‐metabolome‐wide Mendelian randomization study
A Moayyeri, CL Cheung, KCB Tan, JA Morris, A Cerani, RP Mohney, ...
Journal of Bone and Mineral Research 33 (4), 643-650, 2018
622018
Genome-wide association study of extreme high bone mass: contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes
CL Gregson, F Newell, PJ Leo, GR Clark, L Paternoster, M Marshall, ...
Bone 114, 62-71, 2018
602018
Childhood obesity and multiple sclerosis: A Mendelian randomization study
A Harroud, RE Mitchell, TG Richardson, JA Morris, V Forgetta, ...
Multiple Sclerosis Journal 27 (14), 2150-2158, 2021
592021
Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq
HH Wessels, A Méndez-Mancilla, Y Hao, E Papalexi, WM Mauck III, L Lu, ...
Nature methods 20 (1), 86-94, 2023
492023
An effector index to predict target genes at GWAS loci
V Forgetta, L Jiang, NA Vulpescu, MS Hogan, S Chen, JA Morris, S Grinek, ...
Human Genetics 141 (8), 1431-1447, 2022
49*2022
FAM210A is a novel determinant of bone and muscle structure and strength
K Tanaka, Y Xue, L Nguyen-Yamamoto, JA Morris, I Kanazawa, ...
Proceedings of the National Academy of Sciences 115 (16), E3759-E3768, 2018
492018
Genetic predisposition to increased serum calcium, bone mineral density, and fracture risk in individuals with normal calcium levels: mendelian randomisation study
A Cerani, S Zhou, V Forgetta, JA Morris, K Trajanoska, F Rivadeneira, ...
bmj 366, 2019
472019
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