Whole genome comparison of a large collection of mycobacteriophages reveals a continuum of phage genetic diversity WH Pope, CA Bowman, DA Russell, D Jacobs-Sera, DJ Asai, ... elife 4, e06416, 2015 | 315 | 2015 |
An expanded universe of cancer targets WC Hahn, JS Bader, TP Braun, A Califano, PA Clemons, BJ Druker, ... Cell 184 (5), 1142-1155, 2021 | 174 | 2021 |
Cancer cells educate natural killer cells to a metastasis-promoting cell state IS Chan, H Knútsdóttir, G Ramakrishnan, V Padmanaban, M Warrier, ... Journal of Cell Biology 219 (9), 2020 | 128 | 2020 |
Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin EM Grasset, M Dunworth, G Sharma, M Loth, J Tandurella, ... Science translational medicine 14 (656), eabn7571, 2022 | 107 | 2022 |
DFMO and 5-azacytidine increase M1 macrophages in the tumor microenvironment of murine ovarian cancer M Travers, SM Brown, M Dunworth, CE Holbert, KR Wiehagen, ... Cancer research 79 (13), 3445-3454, 2019 | 82 | 2019 |
Polyamine homeostasis in Snyder-Robinson syndrome T Murray-Stewart, M Dunworth, JR Foley, CE Schwartz, RA Casero Jr Medical sciences 6 (4), 112, 2018 | 46 | 2018 |
DOT1L is a novel cancer stem cell target for triple-negative breast cancer H Kurani, SF Razavipour, KB Harikumar, M Dunworth, AJ Ewald, A Nasir, ... Clinical cancer research 28 (9), 1948-1965, 2022 | 45 | 2022 |
Activation of endoplasmic reticulum stress response by enhanced polyamine catabolism is important in the mediation of cisplatin-induced acute kidney injury K Zahedi, S Barone, C Destefano-Shields, M Brooks, T Murray-Stewart, ... PLoS One 12 (9), e0184570, 2017 | 39 | 2017 |
Autophagy induction by exogenous polyamines is an artifact of bovine serum amine oxidase activity in culture serum CE Holbert, M Dunworth, JR Foley, TT Dunston, TM Stewart, RA Casero Journal of Biological Chemistry 295 (27), 9061-9068, 2020 | 38 | 2020 |
Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies T Murray-Stewart, M Dunworth, Y Lui, FM Giardiello, PM Woster, ... PLoS One 13 (8), e0202677, 2018 | 35 | 2018 |
Dual inhibitors of LSD1 and spermine oxidase S Holshouser, M Dunworth, T Murray-Stewart, YK Peterson, P Burger, ... MedChemComm 10 (5), 778-790, 2019 | 25 | 2019 |
Engineering a 3D collective cancer invasion model with control over collagen fiber alignment CY Su, A Burchett, M Dunworth, JS Choi, AJ Ewald, EH Ahn, DH Kim Biomaterials 275, 120922, 2021 | 24 | 2021 |
A new class of cytotoxic agents targets tubulin and disrupts microtubule dynamics AA Al-Hamashi, R Koranne, S Dlamini, A Alqahtani, E Karaj, MS Rashid, ... Bioorganic chemistry 116, 105297, 2021 | 17 | 2021 |
Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex J McKenna III, D Kapfhamer, JM Kinchen, B Wasek, M Dunworth, ... Human molecular genetics 27 (12), 2113-2124, 2018 | 17 | 2018 |
Ablation of polyamine catabolic enzymes provokes Purkinje cell damage, neuroinflammation, and severe ataxia K Zahedi, M Brooks, S Barone, N Rahmati, T Murray Stewart, M Dunworth, ... Journal of neuroinflammation 17, 1-21, 2020 | 11 | 2020 |
Polymeric prodrugs targeting polyamine metabolism inhibit Zika virus replication NK Routhu, Y Xie, M Dunworth, RA Casero Jr, D Oupicky, SN Byrareddy Molecular pharmaceutics 15 (9), 4284-4295, 2018 | 11 | 2018 |
Triple negative breast tumors contain heterogeneous cancer cells expressing distinct KRAS-dependent collective and disseminative invasion programs E Henriet, H Knutsdottir, EM Grasset, M Dunworth, M Haynes, JS Bader, ... Oncogene 42 (10), 737-747, 2023 | 10 | 2023 |
Hyperglycemic conditions proliferate triple negative breast cancer cells: role of ornithine decarboxylase CC Capellen, J Ortega-Rodas, MJ Morwitzer, HMN Tofilau, M Dunworth, ... Breast cancer research and treatment 190, 255-264, 2021 | 9 | 2021 |
Elevation of cellular Mg2+ levels by the Mg2+ transporter, Alr1, supports growth of polyamine-deficient Saccharomyces cerevisiae cells AS Hanner, M Dunworth, RA Casero, CW MacDiarmid, MH Park Journal of Biological Chemistry 294 (45), 17131-17142, 2019 | 7 | 2019 |
Intra-and Interpatient Drug Response Heterogeneity Exist in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Nongynecologic Cancers SN Radomski, M Dunworth, JJ West, JB Greer, FM Johnston, AJ Ewald Annals of surgical oncology 31 (3), 1996-2007, 2024 | 3 | 2024 |