LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity P Gomez-Suaga, P Rivero-Ríos, E Fdez, M Blanca Ramirez, I Ferrer, ... Human molecular genetics 23 (25), 6779-6796, 2014 | 184 | 2014 |
The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A P Rivero-Ríos, M Romo-Lozano, J Madero-Pérez, AP Thomas, A Biosa, ... Journal of Biological Chemistry 294 (13), 4738-4758, 2019 | 77 | 2019 |
Targeting the autophagy/lysosomal degradation pathway in Parkinson s disease P Rivero-Ríos, J Madero-Pérez, B Fernández, S Hilfiker Current neuropharmacology 14 (3), 238-249, 2016 | 75 | 2016 |
Upstream deregulation of calcium signaling in Parkinson’s disease P Rivero-Ríos, P Gómez-Suaga, E Fdez, S Hilfiker Frontiers in molecular neuroscience 7, 53, 2014 | 62 | 2014 |
Roles of PIKfyve in multiple cellular pathways P Rivero-Ríos, LS Weisman Current Opinion in Cell Biology 76, 102086, 2022 | 59 | 2022 |
Novel insights into the neurobiology underlying LRRK2-linked Parkinson's disease P Gómez-Suaga, E Fdez, B Fernández, M Martínez-Salvador, ... Neuropharmacology 85, 45-56, 2014 | 39 | 2014 |
Alterations in late endocytic trafficking related to the pathobiology of LRRK2-linked Parkinson's disease P Rivero-Ríos, P Gómez-Suaga, B Fernández, J Madero-Pérez, ... Biochemical Society Transactions 43 (3), 390-395, 2015 | 38 | 2015 |
Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes SSP Giridharan, G Luo, P Rivero-Rios, N Steinfeld, H Tronchere, A Singla, ... Elife 11, e69709, 2022 | 36 | 2022 |
Distinct roles for RAB10 and RAB29 in pathogenic LRRK2-mediated endolysosomal trafficking alterations P Rivero-Ríos, M Romo-Lozano, B Fernández, E Fdez, S Hilfiker Cells 9 (7), 1719, 2020 | 34 | 2020 |
LRRK2-Related Parkinson’s disease due to altered endolysosomal biology with variable lewy body pathology: A hypothesis P Rivero-Ríos, M Romo-Lozano, R Fasiczka, Y Naaldijk, S Hilfiker Frontiers in Neuroscience 14, 556, 2020 | 34 | 2020 |
LRRK2 and Parkinson's disease: from lack of structure to gain of function M Blanca Ramirez, J Madero-Perez, P Rivero-Rios, M Martinez-Salvador, ... Current Protein and Peptide Science 18 (7), 677-686, 2017 | 32 | 2017 |
Cellular effects mediated by pathogenic LRRK2: homing in on Rab-mediated processes J Madero-Pérez, E Fdez, B Fernández, AJ Lara Ordonez, ... Biochemical Society Transactions 45 (1), 147-154, 2017 | 15 | 2017 |
Two-pore channels and parkinson’s disease: where’s the link? P Rivero-Ríos, B Fernández, J Madero-Pérez, MR Lozano, S Hilfiker Messenger (Los Angeles, Calif.: Print) 5 (1-2), 67, 2016 | 12 | 2016 |
Iron-induced cytotoxicity mediated by endolysosomal TRPML1 channels is reverted by TFEB B Fernández, P Olmedo, F Gil, E Fdez, Y Naaldijk, P Rivero-Ríos, ... Cell Death & Disease 13 (12), 1047, 2022 | 11 | 2022 |
Upregulation of the ESCRT pathway and multivesicular bodies accelerates degradation of proteins associated with neurodegeneration R Benyair, SS Panapakkam Giridharan, P Rivero-Ríos, J Hasegawa, ... Autophagy reports 2 (1), 2166722, 2023 | 9 | 2023 |
Recruitment of the SNX17-Retriever recycling pathway regulates synaptic function and plasticity P Rivero-Ríos, T Tsukahara, T Uygun, A Chen, GD Chavis, ... Journal of Cell Biology 222 (7), e202207025, 2023 | 8 | 2023 |
Basic Science and Pathogenesis P Rivero-Rios, T Uygun, GD Chavis, MA Sutton, LS Weisman Alzheimer's & dementia: the journal of the Alzheimer's Association 20, e086935, 2024 | | 2024 |
Defects in the signaling lipid PI3P may contribute to dendritic spine loss in Alzheimer’s disease P Rivero‐Rios, T Uygun, GD Chavis, MA Sutton, LS Weisman Alzheimer's & Dementia 20, e086935, 2024 | | 2024 |
The SNX17-Retriever endosomal recycling pathway is a key regulator of synaptic function and plasticity in hippocampal neurons G Chavis, P Rivero-Rios, T Tsukahara, T Uygun, S Iwase, L Weisman, ... Physiology 39 (S1), 665, 2024 | | 2024 |
A signaling lipid drives synapse formation P Rivero-Ríos, LS Weisman Science 382 (6667), 155-156, 2023 | | 2023 |