| Structures of γ-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5′-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with γ-ethynyl-GABA and with the … P Storici, D De Biase, F Bossa, S Bruno, A Mozzarelli, C Peneff, ... Journal of Biological Chemistry 279 (1), 363, 2004 | 191 | 2004 |
| Structural basis for the oxidation of thiosulfate by a sulfur cycle enzyme VA Bamford, S Bruno, T Rasmussen, C Appia‐Ayme, MR Cheesman, ... The EMBO journal, 2002 | 180 | 2002 |
| New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels C Viappiani, S Bettati, S Bruno, L Ronda, S Abbruzzetti, A Mozzarelli, ... Proceedings of the National Academy of Sciences 101 (40), 14414-14419, 2004 | 130 | 2004 |
| The SoxYZ complex carries sulfur cycle intermediates on a peptide swinging arm V Sauvé, S Bruno, BC Berks, AM Hemmings Journal of Biological Chemistry 282 (32), 23194-23204, 2007 | 120 | 2007 |
| High and low oxygen affinity conformations of T state hemoglobin S Bruno, M Bonaccio, S Bettati, C Rivetti, C Viappiani, S Abbruzzetti, ... Protein Science 10 (11), 2401-2407, 2001 | 113 | 2001 |
| Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions A Mozzarelli, L Ronda, S Faggiano, S Bettati, S Bruno Blood transfusion 8 (Suppl 3), s59, 2010 | 108 | 2010 |
| Enzymes from marine polar regions and their biotechnological applications S Bruno, D Coppola, G di Prisco, D Giordano, C Verde Marine drugs 17 (10), 544, 2019 | 101 | 2019 |
| Time-resolved methods in Biophysics. 2. Monitoring haem proteins at work with nanosecond laser flash photolysis S Abbruzzetti, S Bruno, S Faggiano, E Grandi, A Mozzarelli, C Viappiani Photochemical & Photobiological Sciences 5, 1109-1120, 2006 | 77 | 2006 |
| The reactivity with CO of AHb1 and AHb2 from Arabidopsis thaliana is controlled by the distal HisE7 and internal hydrophobic cavities S Bruno, S Faggiano, F Spyrakis, A Mozzarelli, S Abbruzzetti, E Grandi, ... Journal of the American Chemical Society 129 (10), 2880-2889, 2007 | 71 | 2007 |
| Ligand migration through the internal hydrophobic cavities in human neuroglobin S Abbruzzetti, S Faggiano, S Bruno, F Spyrakis, A Mozzarelli, S Dewilde, ... Proceedings of the National Academy of Sciences 106 (45), 18984-18989, 2009 | 65 | 2009 |
| Functional properties of the active core of human cystathionine β-synthase crystals S Bruno, F Schiaretti, P Burkhard, JP Kraus, M Janosik, A Mozzarelli Journal of Biological Chemistry 276 (1), 16-19, 2001 | 65 | 2001 |
| UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism I Dando, R Pacchiana, E Dalla Pozza, I Cataldo, S Bruno, P Conti, ... Free Radical Biology and Medicine 113, 176-189, 2017 | 63 | 2017 |
| PEGylation promotes hemoglobin tetramer dissociation D Caccia, L Ronda, R Frassi, M Perrella, E Del Favero, S Bruno, B Pioselli, ... Bioconjugate chemistry 20 (7), 1356-1366, 2009 | 61 | 2009 |
| Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity G Butera, R Pacchiana, N Mullappilly, M Margiotta, S Bruno, P Conti, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865 (12), 1914-1923, 2018 | 59 | 2018 |
| Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria S Bruno, A Pinto, G Paredi, L Tamborini, C De Micheli, V La Pietra, ... Journal of Medicinal Chemistry 57 (17), 7465-7471, 2014 | 57 | 2014 |
| Towards a novel haemoglobin-based oxygen carrier: Euro-PEG-Hb, physico-chemical properties, vasoactivity and renal filtration I Portörő, L Kocsis, P Herman, D Caccia, M Perrella, L Ronda, S Bruno, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (10), 1402-1409, 2008 | 53 | 2008 |
| Functional and Spectroscopic Characterization of Half-Liganded Iron−Zinc Hybrid Hemoglobin: Evidence for Conformational Plasticity within the T State, U Samuni, L Juszczak, D Dantsker, I Khan, AJ Friedman, ... Biochemistry 42 (27), 8272-8288, 2003 | 53 | 2003 |
| Trapping of the thioacylglyceraldehyde-3-phosphate dehydrogenase intermediate from Bacillus stearothermophilus: direct evidence for a flip-flop mechanism S Moniot, S Bruno, C Vonrhein, C Didierjean, S Boschi-Muller, M Vas, ... Journal of Biological Chemistry 283 (31), 21693-21702, 2008 | 46 | 2008 |
| From hemoglobin allostery to hemoglobin-based oxygen carriers S Faggiano, L Ronda, S Bruno, S Abbruzzetti, C Viappiani, S Bettati, ... Molecular Aspects of Medicine 84, 101050, 2022 | 42 | 2022 |
| Experiments on hemoglobin in single crystals and silica gels distinguish among allosteric models ER Henry, A Mozzarelli, C Viappiani, S Abbruzzetti, S Bettati, L Ronda, ... Biophysical Journal 109 (6), 1264-1272, 2015 | 42 | 2015 |
