Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia AG Kotini, CJ Chang, A Chow, H Yuan, TC Ho, T Wang, S Vora, ... Cell stem cell 20 (3), 315-328. e7, 2017 | 156 | 2017 |
Multitask learning improves prediction of cancer drug sensitivity H Yuan, I Paskov, H Paskov, AJ González, CS Leslie Scientific reports 6 (1), 31619, 2016 | 120 | 2016 |
Drosophila Muller F Elements Maintain a Distinct Set of Genomic Properties Over 40 Million Years of Evolution W Leung, CD Shaffer, LK Reed, ST Smith, W Barshop, W Dirkes, ... G3: Genes, Genomes, Genetics 5 (5), 719-740, 2015 | 110 | 2015 |
Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation J Dalal, JH Roh, SE Maloney, A Akuffo, S Shah, H Yuan, B Wamsley, ... Genes & development 27 (5), 565-578, 2013 | 101 | 2013 |
scBasset: sequence-based modeling of single-cell ATAC-seq using convolutional neural networks H Yuan, DR Kelley Nature Methods 19 (9), 1088-1096, 2022 | 86 | 2022 |
Novel insights from a multiomics dissection of the Hayflick limit M Chan, H Yuan, I Soifer, TM Maile, RY Wang, A Ireland, JJ O'Brien, ... Elife 11, e70283, 2022 | 74 | 2022 |
Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets T Wang, AR Pine, AG Kotini, H Yuan, L Zamparo, DT Starczynowski, ... Cell Stem Cell 28 (6), 1074-1089. e7, 2021 | 59 | 2021 |
Predicting RNA-seq coverage from DNA sequence as a unifying model of gene regulation J Linder, D Srivastava, H Yuan, V Agarwal, DR Kelley bioRxiv, 2023.08. 30.555582, 2023 | 55 | 2023 |
Cluster M mycobacteriophages Bongo, PegLeg, and Rey with unusually large repertoires of tRNA isotypes WH Pope, KR Anders, M Baird, CA Bowman, MM Boyle, GW Broussard, ... Journal of virology 88 (5), 2461-2480, 2014 | 54 | 2014 |
Acute myeloid leukemia iPSCs reveal a role for RUNX1 in the maintenance of human leukemia stem cells J Wesely, AG Kotini, F Izzo, H Luo, H Yuan, J Sun, M Georgomanoli, ... Cell reports 31 (9), 2020 | 46 | 2020 |
Individual cell types in C. elegans age differently and activate distinct cell-protective responses AE Roux, H Yuan, K Podshivalova, D Hendrickson, R Kerr, C Kenyon, ... Cell Reports 42 (8), 2023 | 45 | 2023 |
BindSpace decodes transcription factor binding signals by large-scale sequence embedding H Yuan, M Kshirsagar, L Zamparo, Y Lu, CS Leslie Nature methods 16 (9), 858-861, 2019 | 41 | 2019 |
Novel extragenic genomic safe harbors for precise therapeutic T-cell engineering A Odak, H Yuan, J Feucht, VA Cantu, J Mansilla-Soto, F Kogel, J Eyquem, ... Blood, The Journal of the American Society of Hematology 141 (22), 2698-2712, 2023 | 23 | 2023 |
The complete cell atlas of an aging multicellular organism AE Roux, H Yuan, K Podshivalova, D Hendrickson, R Kerr, C Kenyon, ... bioRxiv, 2022.06. 15.496201, 2022 | 16 | 2022 |
BindVAE: Dirichlet variational autoencoders for de novo motif discovery from accessible chromatin M Kshirsagar, H Yuan, JL Ferres, C Leslie Genome Biology 23 (1), 174, 2022 | 14 | 2022 |
Investigation of Maternal Genotype Effects in Autism by Genome‐Wide Association H Yuan, JD Dougherty Autism Research 7 (2), 245-253, 2014 | 8 | 2014 |
Globin vector regulatory elements are active in early hematopoietic progenitor cells A Cabriolu, A Odak, L Zamparo, H Yuan, CS Leslie, M Sadelain Molecular Therapy 30 (6), 2199-2209, 2022 | 5 | 2022 |
Author Correction: scBasset: sequence-based modeling of single-cell ATAC-seq using convolutional neural networks H Yuan, DR Kelley Nature Methods 20 (1), 162-162, 2023 | 4 | 2023 |
Targeted Integration of a CAR at a Novel Genomic Safe Harbor Directs Potent Therapeutic Outcomes A Odak, H Yuan, J Feucht, J Mansilla-Soto, J Eyquem, C Leslie, ... Blood 136, 28, 2020 | 2 | 2020 |
Novel Genomic Safe Harbors for Effective CAR T Cell Engineering A Odak, H Yuan, J Mansilla-Soto, J Eyquem, P Vedantam, C Leslie, ... MOLECULAR THERAPY 27 (4), 433-433, 2019 | 2 | 2019 |