| Parathyroid hormone regulation of the rat collagenase-3 promoter by protein kinase A-dependent transactivation of core binding factor α1 N Selvamurugan, MR Pulumati, DR Tyson, NC Partridge Journal of Biological Chemistry 275 (7), 5037-5042, 2000 | 226 | 2000 |
| Quantifying drug combination synergy along potency and efficacy axes CT Meyer, DJ Wooten, BB Paudel, J Bauer, KN Hardeman, D Westover, ... Cell systems 8 (2), 97-108. e16, 2019 | 181 | 2019 |
| O-sulfonation of serine and threonine: mass spectrometric detection and characterization of a new posttranslational modification in diverse proteins throughout the eukaryotes KF Medzihradszky, Z Darula, E Perlson, M Fainzilber, RJ Chalkley, H Ball, ... Molecular & Cellular Proteomics 3 (5), 429-440, 2004 | 173 | 2004 |
| Periprostatic adipose tissue as a modulator of prostate cancer aggressiveness DS Finley, VS Calvert, J Inokuchi, A Lau, N Narula, EF Petricoin, ... The Journal of urology 182 (4), 1621-1627, 2009 | 167 | 2009 |
| Fractional proliferation: a method to deconvolve cell population dynamics from single-cell data DR Tyson, SP Garbett, PL Frick, V Quaranta Nature methods 9 (9), 923-928, 2012 | 126 | 2012 |
| An unbiased metric of antiproliferative drug effect in vitro LA Harris, PL Frick, SP Garbett, KN Hardeman, BB Paudel, CF Lopez, ... Nature methods 13 (6), 497-500, 2016 | 118 | 2016 |
| Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers DJ Wooten, SM Groves, DR Tyson, Q Liu, JS Lim, R Albert, CF Lopez, ... PLoS computational biology 15 (10), e1007343, 2019 | 112 | 2019 |
| Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer AB Hanker, MV Estrada, G Bianchini, PD Moore, J Zhao, F Cheng, ... Cancer research 77 (12), 3280-3292, 2017 | 106 | 2017 |
| Bone marrow stem cells for urologic tissue engineering D Shukla, GN Box, RA Edwards, DR Tyson World Journal of Urology 26, 341-349, 2008 | 105 | 2008 |
| Reverse-phase protein array profiling of oropharyngeal cancer and significance of PIK3CA mutations in HPV-associated head and neck cancer A Sewell, B Brown, A Biktasova, GB Mills, Y Lu, DR Tyson, N Issaeva, ... Clinical cancer research 20 (9), 2300-2311, 2014 | 100 | 2014 |
| Network analysis of the focal adhesion to invadopodia transition identifies a PI3K-PKCα invasive signaling axis D Hoshino, J Jourquin, SW Emmons, T Miller, M Goldgof, K Costello, ... Science signaling 5 (241), ra66-ra66, 2012 | 99 | 2012 |
| The impact of altered annexin I protein levels on apoptosis and signal transduction pathways in prostate cancer cells CH Hsiang, T Tunoda, YE Whang, DR Tyson, DK Ornstein The Prostate 66 (13), 1413-1424, 2006 | 95 | 2006 |
| Annexin A2 positively contributes to the malignant phenotype and secretion of IL‐6 in DU145 prostate cancer cells J Inokuchi, N Narula, DS Yee, DW Skarecky, A Lau, DK Ornstein, ... International journal of cancer 124 (1), 68-74, 2009 | 85 | 2009 |
| Increased Osteoblastic c-fos Expression by Parathyroid Hormone Requires Protein Kinase A Phosphorylation of the Cyclic Adenosine 3′,5′-Monophosphate … DR Tyson, JT Swarthout, NC Partridge Endocrinology 140 (3), 1255-1261, 1999 | 78 | 1999 |
| The contribution of age structure to cell population responses to targeted therapeutics P Gabriel, SP Garbett, V Quaranta, DR Tyson, GF Webb Journal of theoretical biology 311, 19-27, 2012 | 68 | 2012 |
| Proteomics for the identification of new prostate cancer biomarkers DK Ornstein, DR Tyson Urologic Oncology: Seminars and Original Investigations 24 (3), 231-236, 2006 | 68 | 2006 |
| Dependence on glycolysis sensitizes BRAF-mutated melanomas for increased response to targeted BRAF inhibition KN Hardeman, C Peng, BB Paudel, CT Meyer, T Luong, DR Tyson, ... Scientific reports 7 (1), 42604, 2017 | 63 | 2017 |
| A predictive mathematical modeling approach for the study of doxorubicin treatment in triple negative breast cancer MT McKenna, JA Weis, SL Barnes, DR Tyson, MI Miga, V Quaranta, ... Scientific reports 7 (1), 5725, 2017 | 59 | 2017 |
| Inhibition of phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model T Tsunoda, T Ota, T Fujimoto, K Doi, Y Tanaka, Y Yoshida, M Ogawa, ... Molecular cancer 11, 1-12, 2012 | 58 | 2012 |
| Long-term impact of a robot assisted laparoscopic prostatectomy mini fellowship training program on postgraduate urological practice patterns AJR Gamboa, RT Santos, ER Sargent, MK Louie, GN Box, KH Sohn, ... The Journal of urology 181 (2), 778-782, 2009 | 58 | 2009 |
