Synthesis of 2-arylated thiadiazolopyrimidones by Suzuki–Miyaura cross-coupling: A new class of nucleotide pyrophosphatase (NPPs) inhibitors B Jafari, N Yelibayeva, M Ospanov, SA Ejaz, S Afzal, SU Khan, ZA Abilov, ... RSC advances 6 (109), 107556-107571, 2016 | 41 | 2016 |
Exploration of carboxy pyrazole derivatives: Synthesis, alkaline phosphatase, nucleotide pyrophosphatase/phosphodiesterase and nucleoside triphosphate diphosphohydrolase … PA Channar, S Afzal, SA Ejaz, A Saeed, FA Larik, PA Mahesar, J Lecka, ... European Journal of Medicinal Chemistry 156, 461-478, 2018 | 37 | 2018 |
Synthesis, spectral analysis and anti-bacterial study of N-substituted derivatives of 2-(5-(1-(phenylsulfonyl) piperidin-4-yl)-1, 3, 4-oxadiazol-2-ylthio) acetamide H Khalid, MA Abbasi, A Malik, S Rasool, K Nafeesa, I Ahmad, S Afzal Journal of Saudi Chemical Society 20, S615-S623, 2016 | 34 | 2016 |
Hydrazine clubbed 1, 3-thiazoles as potent urease inhibitors: design, synthesis and molecular docking studies PA Channar, A Saeed, S Afzal, D Hussain, M Kalesse, SA Shehzadi, ... Molecular Diversity 25, 1-13, 2021 | 24 | 2021 |
Investigation of new quinoline derivatives as promising inhibitors of NTPDases: Synthesis, SAR analysis and molecular docking studies K Hayat, S Afzal, A Saeed, A Murtaza, SU Rahman, KM Khan, A Saeed, ... Bioorganic Chemistry 87, 218-226, 2019 | 22 | 2019 |
Synthesis of some new 5-substituted-2-((6-chloro-3, 4-methylenedioxyphenyl) methylthio)-1, 3, 4-Oxadiazole derivatives as suitable antibacterial inhibitors A Siddiqa, MA Abbasi, S Rasool, SZ Siddiqui, I Ahmad, S Afzal Bulletin of Faculty of Pharmacy, Cairo University 53 (1), 37-43, 2015 | 20 | 2015 |
Schiff bases of tryptamine as potent inhibitors of nucleoside triphosphate diphosphohydrolases (NTPDases): structure-activity relationship KM Khan, U Salar, S Afzal, A Wadood, M Taha, S Perveen, H Khan, ... Bioorganic chemistry 82, 253-266, 2019 | 19 | 2019 |
Synthesis, spectral analysis and biological screening of some new N-(un) substituted N-(5-chloro-2-methoxyphenyl)-aryl sulfonamides S Rasool, MA Abbasi, A Fatima, K Nafeesa, I Ahmad, S Afzal Journal of Pharmacy Research 6 (5), 559-564, 2013 | 16 | 2013 |
Deazapurine Analogues Bearing a 1H‐Pyrazolo[3,4‐b]pyridin‐3(2H)‐one Core: Synthesis and Biological Activity L Supe, S Afzal, A Mahmood, SA Ejaz, M Hein, VO Iaroshenko, A Villinger, ... European Journal of Organic Chemistry 2018 (20-21), 2629-2644, 2018 | 12 | 2018 |
Functionalized oxoindolin hydrazine carbothioamide derivatives as highly potent inhibitors of nucleoside triphosphate diphosphohydrolases S Afzal, M Al-Rashida, A Hameed, J Pelletier, J Sévigny, J Iqbal Frontiers in Pharmacology 11, 585876, 2020 | 10 | 2020 |
Chemoselective synthesis and biological evaluation of arylated 2-(Trifluoromethyl) quinolines as nucleotide pyrophosphatase (NPPs) inhibitors D Kuhrt, SA Ejaz, S Afzal, SU Khan, J Lecka, J Sévigny, P Ehlers, ... European Journal of Medicinal Chemistry 138, 816-829, 2017 | 9 | 2017 |
Divergent synthesis and elaboration of structure activity relationship for quinoline derivatives as highly selective NTPDase inhibitor A Murtaza, S Afzal, G Zaman, A Saeed, J Pelletier, J Sévigny, J Iqbal, ... Bioorganic Chemistry 115, 105240, 2021 | 8 | 2021 |
Highly Potent and Selective Ectonucleoside Triphosphate Diphosphohydrolase (ENTPDase1, 2, 3 and 8) Inhibitors Having 2-substituted-7-Trifluoromethyl-Thiadiazolopyrimidones Scaffold S Afzal, S Zaib, B Jafari, P Langer, J Lecka, J Sévigny, J Iqbal Medicinal Chemistry 16 (5), 689-702, 2020 | 8 | 2020 |
Synthesis, In-vitro evaluation and molecular docking studies of oxoindolin phenylhydrazine carboxamides as potent and selective inhibitors of ectonucleoside triphosphate … S Afzal, M Al-Rashida, A Hameed, J Pelletier, J Sévigny, J Iqbal Bioorganic Chemistry 112, 104957, 2021 | 7 | 2021 |
Synthesis, structural analysis, and screening of some novel 5-substituted aryl/aralkyl-1, 3, 4-oxadiazol-2-yl 4-(morpholin-4-ylsulfonyl) benzyl sulfides as potential … Aziz-ur-Rehman, S Gul, MA Abbasi, K Nafeesa, MN Akhtar, I Ahmad, ... Phosphorus, Sulfur, and Silicon and the Related Elements 190 (7), 1045-1055, 2015 | 7 | 2015 |
Synthesis and antibacterial evaluation of 2-(1, 3-Benzodioxol-5-ylcarbonyl) arylsulfonohydrazide derivatives A Siddiqa, A Rehman, MA Abbasi, S Rasool, KM Khan, I Ahmad, S Afzal Tropical Journal of Pharmaceutical Research 13 (10), 1689-1696, 2014 | 7 | 2014 |
Synthesis, characterization and biological evaluation of thiadiazole amide derivatives as nucleoside triphosphate diphosphohydrolases (NTPDases) inhibitors S Abbas, S Afzal, H Nadeem, D Hussain, P Langer, J Sévigny, Z Ashraf, ... Bioorganic Chemistry 118, 105456, 2022 | 4 | 2022 |
Synthesis and antibacterial screening of S-substituted derivatives of 5-(3, 4-methylenedioxyphenyl)-1, 3, 4-oxadiazol-2-thiol. A Siddiqa, MA Abbasi, SZ Siddiqui, S Rasool, A Sattar, KM Khan, I Ahmad, ... Pakistan journal of pharmaceutical sciences 29 (1), 2016 | 4 | 2016 |
Synthesis, Characterization and Antibacterial Activity of Halogenated Aryl Sulfonamides Derived from 2-Amino-4-chloroanisole. S Rasool, MA Abbasi, K Nafeesa, A Fatima, S Gul, G Hussain, KM Khan, ... Journal of the Chemical Society of Pakistan 36 (3), 2014 | 3 | 2014 |
Synthesis, Characterization and Biological Activity of Some New S-Substituted Derivatives of 5-(2-Chlorophenyl)-1, 3, 4-Oxadiazol-2-Thiol. S Rasool, MA Abbasi, SZ Siddiqui, A Sattar, KM Khan, I Ahmad, S Afzal Journal of the Chemical Society of Pakistan 37 (4), 2015 | 2 | 2015 |