Inhibition of tumor-derived prostaglandin-e2 blocks the induction of myeloid-derived suppressor cells and recovers natural killer cell activity Y Mao, D Sarhan, A Steven, B Seliger, R Kiessling, A Lundqvist Clinical cancer research 20 (15), 4096-4106, 2014 | 309 | 2014 |
Natural killer cell-based therapies targeting cancer: possible strategies to gain and sustain anti-tumor activity CIM Dahlberg, D Sarhan, M Chrobok, AD Duru, E Alici Frontiers in immunology 6, 605, 2015 | 240 | 2015 |
Adaptive NK cells with low TIGIT expression are inherently resistant to myeloid-derived suppressor cells D Sarhan, F Cichocki, B Zhang, A Yingst, SR Spellman, S Cooley, ... Cancer research 76 (19), 5696-5706, 2016 | 217 | 2016 |
Distinct developmental pathways from blood monocytes generate human lung macrophage diversity E Evren, E Ringqvist, KP Tripathi, N Sleiers, IC Rives, A Alisjahbana, ... Immunity 54 (2), 259-275. e7, 2021 | 173 | 2021 |
Selenium stimulates the antitumour immunity: Insights to future research A Razaghi, M Poorebrahim, D Sarhan, M Björnstedt European Journal of Cancer 155, 256-267, 2021 | 170 | 2021 |
Targeting MARCO and IL37R on immunosuppressive macrophages in lung cancer blocks regulatory T cells and supports cytotoxic lymphocyte function L La Fleur, J Botling, F He, C Pelicano, C Zhou, C He, G Palano, ... Cancer Research 81 (4), 956-967, 2021 | 161 | 2021 |
GSK3 inhibition drives maturation of NK cells and enhances their antitumor activity F Cichocki, B Valamehr, R Bjordahl, B Zhang, B Rezner, P Rogers, ... Cancer research 77 (20), 5664-5675, 2017 | 156 | 2017 |
Targeting a scavenger receptor on tumor-associated macrophages activates tumor cell killing by natural killer cells S Eisinger, D Sarhan, VF Boura, I Ibarlucea-Benitez, S Tyystjärvi, ... Proceedings of the National Academy of Sciences 117 (50), 32005-32016, 2020 | 129 | 2020 |
161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS D Sarhan, L Brandt, M Felices, K Guldevall, T Lenvik, P Hinderlie, ... Blood advances 2 (12), 1459-1469, 2018 | 118 | 2018 |
Haploidentical natural killer cells induce remissions in non-Hodgkin lymphoma patients with low levels of immune-suppressor cells V Bachanova, D Sarhan, TE DeFor, S Cooley, A Panoskaltsis-Mortari, ... Cancer Immunology, Immunotherapy 67, 483-494, 2018 | 102 | 2018 |
Adaptive NK cells resist regulatory T-cell suppression driven by IL37 D Sarhan, KL Hippen, A Lemire, S Hying, X Luo, T Lenvik, J Curtsinger, ... Cancer immunology research 6 (7), 766-775, 2018 | 99 | 2018 |
Doxorubicin sensitizes human tumor cells to NK cell‐and T‐cell‐mediated killing by augmented TRAIL receptor signaling E Wennerberg, D Sarhan, M Carlsten, VO Kaminskyy, P D'Arcy, ... International journal of cancer 133 (7), 1643-1652, 2013 | 76 | 2013 |
HER2/HER3 signaling regulates NK cell-mediated cytotoxicity via MHC class I chain-related molecule A and B expression in human breast cancer cell lines R Okita, D Mougiakakos, T Ando, Y Mao, D Sarhan, E Wennerberg, ... The Journal of Immunology 188 (5), 2136-2145, 2012 | 75 | 2012 |
Early reconstitution of NK and γδ T cells and its implication for the design of post-transplant immunotherapy MA de Witte, D Sarhan, Z Davis, M Felices, DA Vallera, P Hinderlie, ... Biology of Blood and Marrow Transplantation 24 (6), 1152-1162, 2018 | 73 | 2018 |
Mesenchymal stromal cells shape the MDS microenvironment by inducing suppressive monocytes that dampen NK cell function D Sarhan, J Wang, US Arvindam, C Hallstrom, MR Verneris, B Grzywacz, ... JCI insight 5 (5), 2020 | 54 | 2020 |
Dendritic cell regulation of NK‐cell responses involves lymphotoxin‐α, IL‐12, and TGF‐β D Sarhan, M Palma, Y Mao, L Adamson, R Kiessling, H Mellstedt, ... European journal of immunology 45 (6), 1783-1793, 2015 | 46 | 2015 |
Enhanced stimulation of human tumor-specific T cells by dendritic cells matured in the presence of interferon-γ and multiple toll-like receptor agonists T Lövgren, D Sarhan, I Truxová, B Choudhary, R Maas, J Melief, ... Cancer Immunology, Immunotherapy 66, 1333-1344, 2017 | 44 | 2017 |
Regulation of TRAIL-receptor expression by the ubiquitin-proteasome system D Sarhan, P D’Arcy, A Lundqvist International journal of molecular sciences 15 (10), 18557-18573, 2014 | 34 | 2014 |
Activated monocytes augment TRAIL‐mediated cytotoxicity by human NK cells through release of IFN‐γ D Sarhan, P D'Arcy, E Wennerberg, M Lidén, J Hu, O Winqvist, C Rolny, ... European journal of immunology 43 (1), 249-257, 2013 | 34 | 2013 |
Independent control of natural killer cell responsiveness and homeostasis at steady-state by CD11c+ dendritic cells TT Luu, S Ganesan, AK Wagner, D Sarhan, S Meinke, N Garbi, ... Scientific reports 6 (1), 37996, 2016 | 26 | 2016 |