The microRNA miR-155 controls CD8+ T cell responses by regulating interferon signaling DT Gracias, E Stelekati, JL Hope, AC Boesteanu, TA Doering, J Norton, ... Nature immunology 14 (6), 593-602, 2013 | 353 | 2013 |
Mir-155 is overexpressed in systemic sclerosis fibroblasts and is required for NLRP3 inflammasome-mediated collagen synthesis during fibrosis CM Artlett, S Sassi-Gaha, JL Hope, CA Feghali-Bostwick, PD Katsikis Arthritis research & therapy 19, 1-8, 2017 | 131 | 2017 |
Acute exposure to ZnO nanoparticles induces autophagic immune cell death BM Johnson, JA Fraietta, DT Gracias, JL Hope, CJ Stairiker, PR Patel, ... Nanotoxicology 9 (6), 737-748, 2015 | 123 | 2015 |
Type I interferon upregulates Bak and contributes to T cell loss during human immunodeficiency virus (HIV) infection JA Fraietta, YM Mueller, G Yang, AC Boesteanu, DT Gracias, DH Do, ... PLoS pathogens 9 (10), e1003658, 2013 | 97 | 2013 |
Long-term persistence of exhausted CD8 T cells in chronic infection is regulated by microRNA-155 E Stelekati, Z Chen, S Manne, M Kurachi, MA Ali, K Lewy, Z Cai, ... Cell reports 23 (7), 2142-2156, 2018 | 95 | 2018 |
FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells JZ Shen, Z Qiu, Q Wu, D Finlay, G Garcia, D Sun, J Rantala, W Barshop, ... Cell 184 (2), 352-369. e23, 2021 | 80 | 2021 |
Rapid in vitro generation of bona fide exhausted CD8+ T cells is accompanied by Tcf7 promotor methylation M Zhao, CH Kiernan, CJ Stairiker, JL Hope, LG Leon, M van Meurs, ... PLoS pathogens 16 (6), e1008555, 2020 | 58 | 2020 |
Lessons in antiviral immunity JL Hope, LM Bradley Science 371 (6528), 464-465, 2021 | 48 | 2021 |
Striking a balance—cellular and molecular drivers of memory T cell development and responses to chronic stimulation JL Hope, CJ Stairiker, EA Bae, DC Otero, LM Bradley Frontiers in immunology 10, 1595, 2019 | 39 | 2019 |
Phosphatidylinositol 3-kinase p110δ isoform regulates CD8+ T cell responses during acute viral and intracellular bacterial infections DT Gracias, AC Boesteanu, JA Fraietta, JL Hope, AJ Carey, YM Mueller, ... The Journal of Immunology 196 (3), 1186-1198, 2016 | 38 | 2016 |
Public Clonotypes and Convergent Recombination Characterize the Naïve CD8+ T-Cell Receptor Repertoire of Extremely Preterm Neonates AJ Carey, JL Hope, YM Mueller, AJ Fike, OK Kumova, DBH van Zessen, ... Frontiers in immunology 8, 1859, 2017 | 33 | 2017 |
The Transcription Factor T-Bet Is Regulated by MicroRNA-155 in Murine Anti-Viral CD8+ T Cells via SHIP-1 JL Hope, CJ Stairiker, PI Spantidea, DT Gracias, AJ Carey, AJ Fike, ... Frontiers in immunology 8, 1696, 2017 | 32 | 2017 |
Rapid evolution of the CD8+ TCR repertoire in neonatal mice AJ Carey, DT Gracias, JL Thayer, AC Boesteanu, OK Kumova, ... The Journal of Immunology 196 (6), 2602-2613, 2016 | 30 | 2016 |
PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion JL Hope, DC Otero, EA Bae, CJ Stairiker, AB Palete, HA Faso, M Lin, ... Cell reports 42 (5), 2023 | 21 | 2023 |
Developmentally distinct CD4+ Treg lineages shape the CD8+ T cell response to acute Listeria infection JS Dolina, J Lee, EL Moore, JL Hope, DT Gracias, T Matsutani, A Chawla, ... Proceedings of the National Academy of Sciences 119 (10), e2113329119, 2022 | 12 | 2022 |
Microenvironment-dependent gradient of CTL exhaustion in the AE17sOVA murine mesothelioma tumor model JL Hope, PI Spantidea, CH Kiernan, CJ Stairiker, LC Rijsbergen, ... Frontiers in immunology 10, 3074, 2020 | 10 | 2020 |
MicroRNA-139 expression is dispensable for the generation of influenza-specific CD8+ T cell responses JL Hope, M Zhao, CJ Stairiker, CH Kiernan, AJ Carey, YM Mueller, ... The Journal of Immunology 208 (3), 603-617, 2022 | 2 | 2022 |
Abasic phosphorothioate oligomers inhibit HIV-1 reverse transcription and block virus transmission across polarized ectocervical organ cultures JA Fraietta, YM Mueller, KL Lozenski, D Ratner, AC Boesteanu, ... Antimicrobial agents and chemotherapy 58 (12), 7056-7071, 2014 | 2 | 2014 |
Macropinocytosis controls metabolic stress-driven CAF subtype identity in pancreatic cancer Y Zhang, L Ling, S Maganti, JL Hope, CM Galapate, F Carrette, ... bioRxiv, 2024.11. 29.625709, 2024 | 1 | 2024 |
RNF5-deficiency inhibits CD8+ T cell exhaustion in chronic antigen stimulation E Bae, JL Hope, DC Otero, HA Faso, AB Palete, ZA Ronai, LM Bradley The Journal of Immunology 206 (1_Supplement), 14.12-14.12, 2021 | 1 | 2021 |