Regulation of bile acid synthesis by the nuclear receptor Rev-erbα H Duez, JN Van Der Veen, C Duhem, B Pourcet, T Touvier, C Fontaine, ... Gastroenterology 135 (2), 689-698. e5, 2008 | 247 | 2008 |
Nuclear receptor subfamily 1 group D member 1 regulates circadian activity of NLRP3 inflammasome to reduce the severity of fulminant hepatitis in mice B Pourcet, M Zecchin, L Ferri, J Beauchamp, S Sitaula, C Billon, ... Gastroenterology 154 (5), 1449-1464. e20, 2018 | 209 | 2018 |
Selective PPAR modulators, dual and pan PPAR agonists: multimodal drugs for the treatment of type 2 diabetes and atherosclerosis B Pourcet, JC Fruchart, B Staels, C Glineur Expert opinion on emerging drugs 11 (3), 379-401, 2006 | 130 | 2006 |
SUMOylation of human peroxisome proliferator-activated receptor α inhibits its trans-activity through the recruitment of the nuclear corepressor NCoR B Pourcet, I Pineda-Torra, B Derudas, B Staels, C Glineur Journal of Biological Chemistry 285 (9), 5983-5992, 2010 | 111 | 2010 |
LXRα regulates macrophage arginase 1 through PU. 1 and interferon regulatory factor 8 B Pourcet, JE Feig, Y Vengrenyuk, AJ Hobbs, D Kepka-Lenhart, ... Circulation research 109 (5), 492-501, 2011 | 103 | 2011 |
The nuclear receptor Rev-erbα is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophages C Fontaine, E Rigamonti, B Pourcet, H Duez, C Duhem, JC Fruchart, ... Molecular endocrinology 22 (8), 1797-1811, 2008 | 94 | 2008 |
Transcriptional regulation of macrophage arginase 1 expression and its role in atherosclerosis B Pourcet, I Pineda-Torra Trends in cardiovascular medicine 23 (5), 143-152, 2013 | 85 | 2013 |
Circadian control of inflammasome pathways: implications for circadian medicine B Pourcet, H Duez Frontiers in immunology 11, 1630, 2020 | 69 | 2020 |
Rev-erb-α regulates atrophy-related genes to control skeletal muscle mass A Mayeuf-Louchart, Q Thorel, S Delhaye, J Beauchamp, C Duhem, ... Scientific reports 7 (1), 14383, 2017 | 65 | 2017 |
Nuclear receptors in the control of the NLRP3 inflammasome pathway H Duez, B Pourcet Frontiers in endocrinology 12, 630536, 2021 | 59 | 2021 |
Impaired LXRα phosphorylation attenuates progression of fatty liver disease N Becares, MC Gage, M Voisin, E Shrestha, L Martin-Gutierrez, N Liang, ... Cell reports 26 (4), 984-995. e6, 2019 | 59 | 2019 |
The nuclear receptor LXR modulates interleukin-18 levels in macrophages through multiple mechanisms B Pourcet, MC Gage, TE León, KE Waddington, OM Pello, KR Steffensen, ... Scientific reports 6 (1), 25481, 2016 | 59 | 2016 |
Glycogen dynamics drives lipid droplet biogenesis during brown adipocyte differentiation A Mayeuf-Louchart, S Lancel, Y Sebti, B Pourcet, A Loyens, S Delhaye, ... Cell reports 29 (6), 1410-1418. e6, 2019 | 57 | 2019 |
Alternative macrophages in atherosclerosis: not always protective! B Pourcet, B Staels The Journal of clinical investigation 128 (3), 910-912, 2018 | 57 | 2018 |
Acetate Improves the Killing of Streptococcus pneumoniae by Alveolar Macrophages via NLRP3 Inflammasome and Glycolysis-HIF-1α Axis MG Machado, TA Patente, Y Rouillé, S Heumel, EM Melo, L Deruyter, ... Frontiers in Immunology 13, 773261, 2022 | 55 | 2022 |
Disrupting LXRα phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation MC Gage, N Bécares, R Louie, KE Waddington, Y Zhang, TH Tittanegro, ... Proceedings of the National Academy of Sciences 115 (28), E6556-E6565, 2018 | 47 | 2018 |
Modulation of macrophage gene expression via liver X receptor α serine 198 phosphorylation C Wu, MA Hussein, E Shrestha, S Leone, MS Aiyegbo, WM Lambert, ... Molecular and cellular biology 35 (11), 2024-2034, 2015 | 32 | 2015 |
Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis M Bobowski-Gerard, C Boulet, FP Zummo, J Dubois-Chevalier, ... Nature Communications 13 (1), 5324, 2022 | 26 | 2022 |
NR1D1 controls skeletal muscle calcium homeostasis through myoregulin repression A Boulinguiez, C Duhem, A Mayeuf-Louchart, B Pourcet, Y Sebti, ... JCI insight 7 (17), e153584, 2022 | 10 | 2022 |
The LPS/D-galactosamine-induced fulminant hepatitis model to assess the role of ligand-activated nuclear receptors on the NLRP3 inflammasome pathway in vivo Y Sebti, L Ferri, M Zecchin, J Beauchamp, D Mogilenko, B Staels, H Duez, ... Lipid-Activated Nuclear Receptors: Methods and Protocols, 189-207, 2019 | 10 | 2019 |