ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection R Karki, SJ Lee, R Mall, N Pandian, Y Wang, BR Sharma, RKS Malireddi, ... Science immunology 7 (74), eabo6294, 2022 | 174 | 2022 |
NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs B Sundaram, N Pandian, R Mall, Y Wang, R Sarkar, HJ Kim, ... Cell 186 (13), 2783-2801. e20, 2023 | 150 | 2023 |
PANoptosis: a unique innate immune inflammatory cell death modality N Pandian, TD Kanneganti The Journal of Immunology 209 (9), 1625-1633, 2022 | 139 | 2022 |
Mevalonate cascade inhibition by simvastatin induces the intrinsic apoptosis pathway via depletion of isoprenoids in tumor cells J Alizadeh, AA Zeki, N Mirzaei, S Tewary, A Rezaei Moghadam, ... Scientific reports 7 (1), 44841, 2017 | 136 | 2017 |
Protective Effect of Calendula officinalis L. Flowers Against Monosodium Glutamate Induced Oxidative Stress and Excitotoxic Brain Damage in Rats BD Shivasharan, P Nagakannan, BS Thippeswamy, VP Veerapur Indian Journal of Clinical Biochemistry 28, 292-298, 2013 | 130 | 2013 |
Effect of embelin against 3-nitropropionic acid-induced Huntington's disease in rats SB Dhadde, P Nagakannan, M Roopesh, SRA Kumar, BS Thippeswamy, ... Biomedicine & Pharmacotherapy 77, 52-58, 2016 | 86 | 2016 |
Protective Effect of Embelin from Embelia ribes Burm. Against Transient Global Ischemia-Induced Brain Damage in Rats BS Thippeswamy, P Nagakannan, BD Shivasharan, S Mahendran, ... Neurotoxicity research 20, 379-386, 2011 | 77 | 2011 |
Cathepsin B is an executioner of ferroptosis P Nagakannan, MI Islam, M Conrad, E Eftekharpour Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1868 (3), 118928, 2021 | 65 | 2021 |
Perturbation of redox balance after thioredoxin reductase deficiency interrupts autophagy-lysosomal degradation pathway and enhances cell death in nutritionally stressed SH … P Nagakannan, MA Iqbal, A Yeung, JA Thliveris, M Rastegar, S Ghavami, ... Free Radical Biology and Medicine 101, 53-70, 2016 | 48 | 2016 |
Protective effect of Calendula officinalis Linn. flowers against 3-nitropropionic acid induced experimental Huntington’s disease in rats BD Shivasharan, P Nagakannan, BS Thippeswamy, VP Veerapur, ... Drug and Chemical Toxicology 36 (4), 466-473, 2013 | 47 | 2013 |
Protective effect of hydroalcoholic extract of Mimusops elengi Linn. flowers against middle cerebral artery occlusion induced brain injury in rats P Nagakannan, BD Shivasharan, BS Thippeswamy, VP Veerapur, ... Journal of ethnopharmacology 140 (2), 247-254, 2012 | 45 | 2012 |
Inhibition of VDAC1 protects against glutamate-induced oxytosis and mitochondrial fragmentation in hippocampal HT22 cells P Nagakannan, MI Islam, S Karimi-Abdolrezaee, E Eftekharpour Cellular and molecular neurobiology 39, 73-85, 2019 | 44 | 2019 |
Effect of tramadol on behavioral alterations and lipid peroxidation after transient forebrain ischemia in rats P Nagakannan, BD Shivasharan, BS Thippeswamy, VP Veerapur Toxicology mechanisms and methods 22 (9), 674-678, 2012 | 42 | 2012 |
Differential redox sensitivity of cathepsin B and L holds the key to autophagy-apoptosis interplay after Thioredoxin reductase inhibition in nutritionally stressed SH-SY5Y cells P Nagakannan, E Eftekharpour Free Radical Biology and Medicine 108, 819-831, 2017 | 39 | 2017 |
Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method Y Wang, N Pandian, JH Han, B Sundaram, SJ Lee, R Karki, CS Guy, ... Cellular and Molecular Life Sciences 79 (10), 531, 2022 | 36 | 2022 |
Upregulation of thioredoxin-interacting protein in brain of amyloid-β protein precursor/presenilin 1 transgenic mice and amyloid-β treated neuronal cells Y Wang, Y Wang, V Bharti, H Zhou, V Hoi, H Tan, Z Wu, P Nagakannan, ... Journal of Alzheimer's Disease 72 (1), 139-150, 2019 | 36 | 2019 |
Oxidative damage of lysosomes in regulated cell death systems: Pathophysiology and pharmacologic interventions P Nagakannan, P Tabeshmehr, E Eftekharpour Free Radical Biology and Medicine 157, 94-127, 2020 | 34 | 2020 |
Sedative and antiepileptic effects of Anthocephalus cadamba Roxb. in mice and rats P Nagakannan, BD Shivasharan, VP Veerapur, BS Thippeswamy Indian journal of pharmacology 43 (6), 699-702, 2011 | 34 | 2011 |
Thioredoxin system as a gatekeeper in caspase-6 activation and nuclear lamina integrity: Implications for Alzheimer's disease MI Islam, P Nagakannan, O Ogungbola, J Djordjevic, BC Albensi, ... Free Radical Biology and Medicine 134, 567-580, 2019 | 33 | 2019 |
Acute upregulation of bone morphogenetic protein-4 regulates endogenous cell response and promotes cell death in spinal cord injury CG Hart, SM Dyck, H Kataria, A Alizadeh, P Nagakannan, JA Thliveris, ... Experimental neurology 325, 113163, 2020 | 30 | 2020 |