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Emily E. Scott
Emily E. Scott
Professor, Department of Medicinal Chemistry, University of Michigan
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα umich.edu - Αρχική σελίδα
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An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution
EE Scott, YA He, MR Wester, MA White, CC Chin, JR Halpert, EF Johnson, ...
Proceedings of the National Academy of Sciences 100 (23), 13196-13201, 2003
4472003
Mapping the pathways for O2 entry into and exit from myoglobin
EE Scott, QH Gibson, JS Olson
Journal of Biological Chemistry 276 (7), 5177-5188, 2001
4042001
Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001
NM DeVore, EE Scott
Nature 482 (7383), 116-119, 2012
3722012
Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl) imidazole at 1.9-Å resolution: insight into the range of P450 conformations and the coordination of …
EE Scott, MA White, YA He, EF Johnson, CD Stout, JR Halpert
Journal of Biological Chemistry 279 (26), 27294-27301, 2004
3622004
Human cytochrome P450 1A1 structure and utility in understanding drug and xenobiotic metabolism
AA Walsh, GD Szklarz, EE Scott
Journal of Biological Chemistry 288 (18), 12932-12943, 2013
3182013
Structures of human cytochrome P-450 2E1: insights into the binding of inhibitors and both small molecular weight and fatty acid substrates
PR Porubsky, KM Meneely, EE Scott
Journal of Biological Chemistry 283 (48), 33698-33707, 2008
2812008
Ligand migration in sperm whale myoglobin
EE Scott, QH Gibson
Biochemistry 36 (39), 11909-11917, 1997
1791997
A critical analysis of the interplay between cytochrome P450 3A and P-glycoprotein: recent insights from knockout and transgenic mice
RAB van Waterschoot, AH Schinkel, EE Scott
Pharmacological reviews 63 (2), 390-410, 2011
1572011
A truncation of 2B subfamily cytochromes P450 yields increased expression levels, increased solubility, and decreased aggregation while retaining function
EE Scott, M Spatzenegger, JR Halpert
Archives of Biochemistry and Biophysics 395 (1), 57-68, 2001
1572001
Diabetic peripheral neuropathy: should a chaperone accompany our therapeutic approach?
KL Farmer, C Li, RT Dobrowsky, EE Scott
Pharmacological reviews 64 (4), 880-900, 2012
1502012
Structures of cytochrome P450 3A4
EE Scott, JR Halpert
Trends in biochemical sciences 30 (1), 5-7, 2005
1502005
Structures of human steroidogenic cytochrome P450 17A1 with substrates
EM Petrunak, NM DeVore, PR Porubsky, EE Scott
Journal of Biological Chemistry 289 (47), 32952-32964, 2014
1312014
Structure of the human lung cytochrome P450 2A13
BD Smith, JL Sanders, PR Porubsky, GH Lushington, CD Stout, EE Scott
Journal of Biological Chemistry 282 (23), 17306-17313, 2007
1262007
Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode
PR Porubsky, KP Battaile, EE Scott
Journal of biological chemistry 285 (29), 22282-22290, 2010
1192010
Waterproofing the heme pocket: role of proximal amino acid side chains in preventing hemin loss from myoglobin
EC Liong, Y Dou, EE Scott, JS Olson, GN Phillips
Journal of Biological Chemistry 276 (12), 9093-9100, 2001
1192001
Substrate-modulated cytochrome P450 17A1 and cytochrome b5 interactions revealed by NMR
DF Estrada, JS Laurence, EE Scott
Journal of Biological Chemistry 288 (23), 17008-17018, 2013
1082013
Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone binding and access channel in human cytochrome P450 2A6 and 2A13 enzymes
NM DeVore, EE Scott
Journal of Biological Chemistry 287 (32), 26576-26585, 2012
902012
Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine
NM DeVore, KM Meneely, AG Bart, ES Stephens, KP Battaile, EE Scott
The FEBS journal 279 (9), 1621-1631, 2012
832012
Illuminating cytochrome P450 binding: Ru (ii)-caged inhibitors of CYP17A1
A Li, R Yadav, JK White, MK Herroon, BP Callahan, I Podgorski, C Turro, ...
Chemical Communications 53 (26), 3673-3676, 2017
822017
Human Cytochrome P450 17A1 Conformational Selection: Modulation by ligand and cytochrome b5
DF Estrada, AL Skinner, JS Laurence, EE Scott
Journal of Biological Chemistry 289 (20), 14310-14320, 2014
792014
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