An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution EE Scott, YA He, MR Wester, MA White, CC Chin, JR Halpert, EF Johnson, ... Proceedings of the National Academy of Sciences 100 (23), 13196-13201, 2003 | 447 | 2003 |
Mapping the pathways for O2 entry into and exit from myoglobin EE Scott, QH Gibson, JS Olson Journal of Biological Chemistry 276 (7), 5177-5188, 2001 | 404 | 2001 |
Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001 NM DeVore, EE Scott Nature 482 (7383), 116-119, 2012 | 372 | 2012 |
Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl) imidazole at 1.9-Å resolution: insight into the range of P450 conformations and the coordination of … EE Scott, MA White, YA He, EF Johnson, CD Stout, JR Halpert Journal of Biological Chemistry 279 (26), 27294-27301, 2004 | 362 | 2004 |
Human cytochrome P450 1A1 structure and utility in understanding drug and xenobiotic metabolism AA Walsh, GD Szklarz, EE Scott Journal of Biological Chemistry 288 (18), 12932-12943, 2013 | 318 | 2013 |
Structures of human cytochrome P-450 2E1: insights into the binding of inhibitors and both small molecular weight and fatty acid substrates PR Porubsky, KM Meneely, EE Scott Journal of Biological Chemistry 283 (48), 33698-33707, 2008 | 281 | 2008 |
Ligand migration in sperm whale myoglobin EE Scott, QH Gibson Biochemistry 36 (39), 11909-11917, 1997 | 179 | 1997 |
A critical analysis of the interplay between cytochrome P450 3A and P-glycoprotein: recent insights from knockout and transgenic mice RAB van Waterschoot, AH Schinkel, EE Scott Pharmacological reviews 63 (2), 390-410, 2011 | 157 | 2011 |
A truncation of 2B subfamily cytochromes P450 yields increased expression levels, increased solubility, and decreased aggregation while retaining function EE Scott, M Spatzenegger, JR Halpert Archives of Biochemistry and Biophysics 395 (1), 57-68, 2001 | 157 | 2001 |
Diabetic peripheral neuropathy: should a chaperone accompany our therapeutic approach? KL Farmer, C Li, RT Dobrowsky, EE Scott Pharmacological reviews 64 (4), 880-900, 2012 | 150 | 2012 |
Structures of cytochrome P450 3A4 EE Scott, JR Halpert Trends in biochemical sciences 30 (1), 5-7, 2005 | 150 | 2005 |
Structures of human steroidogenic cytochrome P450 17A1 with substrates EM Petrunak, NM DeVore, PR Porubsky, EE Scott Journal of Biological Chemistry 289 (47), 32952-32964, 2014 | 131 | 2014 |
Structure of the human lung cytochrome P450 2A13 BD Smith, JL Sanders, PR Porubsky, GH Lushington, CD Stout, EE Scott Journal of Biological Chemistry 282 (23), 17306-17313, 2007 | 126 | 2007 |
Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode PR Porubsky, KP Battaile, EE Scott Journal of biological chemistry 285 (29), 22282-22290, 2010 | 119 | 2010 |
Waterproofing the heme pocket: role of proximal amino acid side chains in preventing hemin loss from myoglobin EC Liong, Y Dou, EE Scott, JS Olson, GN Phillips Journal of Biological Chemistry 276 (12), 9093-9100, 2001 | 119 | 2001 |
Substrate-modulated cytochrome P450 17A1 and cytochrome b5 interactions revealed by NMR DF Estrada, JS Laurence, EE Scott Journal of Biological Chemistry 288 (23), 17008-17018, 2013 | 108 | 2013 |
Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone binding and access channel in human cytochrome P450 2A6 and 2A13 enzymes NM DeVore, EE Scott Journal of Biological Chemistry 287 (32), 26576-26585, 2012 | 90 | 2012 |
Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine NM DeVore, KM Meneely, AG Bart, ES Stephens, KP Battaile, EE Scott The FEBS journal 279 (9), 1621-1631, 2012 | 83 | 2012 |
Illuminating cytochrome P450 binding: Ru (ii)-caged inhibitors of CYP17A1 A Li, R Yadav, JK White, MK Herroon, BP Callahan, I Podgorski, C Turro, ... Chemical Communications 53 (26), 3673-3676, 2017 | 82 | 2017 |
Human Cytochrome P450 17A1 Conformational Selection: Modulation by ligand and cytochrome b5 DF Estrada, AL Skinner, JS Laurence, EE Scott Journal of Biological Chemistry 289 (20), 14310-14320, 2014 | 79 | 2014 |