Casein kinase II phosphorylates IκBα at S-283, S-289, S-293, and T-291 and is required for its degradation JA Mcelhinny, SA Trushin, GD Bren, N Chester, CV Paya Molecular and cellular biology 16 (3), 899-906, 1996 | 240 | 1996 |
Protein kinase C and calcineurin synergize to activate IκB kinase and NF-κB in T lymphocytes SA Trushin, KN Pennington, A Algeciras-Schimnich, CV Paya Journal of Biological Chemistry 274 (33), 22923-22931, 1999 | 229 | 1999 |
Altered brain energetics induces mitochondrial fission arrest in Alzheimer’s Disease L Zhang, S Trushin, TA Christensen, BV Bachmeier, B Gateno, ... Scientific reports 6 (1), 18725, 2016 | 226 | 2016 |
Protein kinase Cα (PKCα) acts upstream of PKCθ to activate IκB kinase and NF-κB in T lymphocytes SA Trushin, KN Pennington, EM Carmona, S Asin, DN Savoy, ... Molecular and cellular biology 23 (19), 7068-7081, 2003 | 165 | 2003 |
Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's disease L Zhang, S Zhang, I Maezawa, S Trushin, P Minhas, M Pinto, LW Jin, ... EBioMedicine 2 (4), 294-305, 2015 | 105 | 2015 |
Bacterial lipopolysaccharide activates HIV long terminal repeat through Toll-like receptor 4 O Equils, E Faure, L Thomas, Y Bulut, S Trushin, M Arditi The Journal of Immunology 166 (4), 2342-2347, 2001 | 97 | 2001 |
Human immunodeficiency virus type 1 protease cleaves procaspase 8 in vivo Z Nie, GD Bren, SR Vlahakis, AA Schimnich, JM Brenchley, SA Trushin, ... Journal of virology 81 (13), 6947-6956, 2007 | 90 | 2007 |
Mitochondrial complex I as a therapeutic target for Alzheimer's disease E Trushina, S Trushin, MF Hasan Acta Pharmaceutica Sinica B 12 (2), 483-495, 2022 | 73 | 2022 |
Human immunodeficiency virus reactivation by phorbol esters or T-cell receptor ligation requires both PKCα and PKCθ SA Trushin, GD Bren, S Asin, KN Pennington, CV Paya, AD Badley Journal of virology 79 (15), 9821-9830, 2005 | 69 | 2005 |
Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice A Stojakovic, S Trushin, A Sheu, L Khalili, SY Chang, X Li, T Christensen, ... Communications biology 4 (1), 61, 2021 | 52 | 2021 |
Autophagy promotes cell survival by maintaining NAD levels T Kataura, L Sedlackova, EG Otten, R Kumari, D Shapira, F Scialo, ... Developmental cell 57 (22), 2584-2598. e11, 2022 | 50 | 2022 |
Glycoprotein 120 binding to CXCR4 causes p38-dependent primary T cell death that is facilitated by, but does not require cell-associated CD4 SA Trushin, A Algeciras-Schimnich, SR Vlahakis, GD Bren, S Warren, ... The Journal of Immunology 178 (8), 4846-4853, 2007 | 48 | 2007 |
Iκκ mediates NF-κB activation in human immunodeficiency virus-infected cells S Asin, JA Taylor, S Trushin, G Bren, CV Paya Journal of virology 73 (5), 3893-3903, 1999 | 44 | 1999 |
Differential effect of amyloid beta peptides on mitochondrial axonal trafficking depends on their state of aggregation and binding to the plasma membrane L Zhang, S Trushin, TA Christensen, U Tripathi, C Hong, RE Geroux, ... Neurobiology of disease 114, 1-16, 2018 | 42 | 2018 |
The signal transduction pathway of CD23 (FcεRIIb) targets IκB kinase RM Ten, MJ McKinstry, SA Trushin, S Asin, CV Paya The Journal of Immunology 163 (7), 3851-3857, 1999 | 42 | 1999 |
Serine 32 and serine 36 of IκBα are directly phosphorylated by protein kinase CKII in vitro JA Taylor, GD Bren, KN Pennington, SA Trushin, S Asin, CV Paya Journal of molecular biology 290 (4), 839-850, 1999 | 38 | 1999 |
HIV gp120 induces, NF-κB dependent, HIV replication that requires procaspase 8 GD Bren, SA Trushin, J Whitman, B Shepard, AD Badley PloS one 4 (3), e4875, 2009 | 31 | 2009 |
A comprehensive approach to sample preparation for electron microscopy and the assessment of mitochondrial morphology in tissue and cultured cells A Hinton Jr, P Katti, TA Christensen, M Mungai, J Shao, L Zhang, ... Advanced biology 7 (10), 2200202, 2023 | 28 | 2023 |
Infected cell killing by HIV-1 protease promotes NF-κB dependent HIV-1 replication GD Bren, J Whitman, N Cummins, B Shepard, SA Rizza, SA Trushin, ... PLoS One 3 (5), e2112, 2008 | 27 | 2008 |
Flying in the Face of Resistance: Antiviral‐independent Benefit of HIV Protease Inhibitors on T‐cell Survival SR Vlahakis, GD Bren, A Algeciras‐Schimnich, SA Trushin, DJ Schnepple, ... Clinical Pharmacology & Therapeutics 82 (3), 294-299, 2007 | 25 | 2007 |