| CRISPR-Cas9 screens identify the RNA helicase DDX3X as a repressor of C9ORF72 (GGGGCC) n repeat-associated non-AUG translation W Cheng, S Wang, Z Zhang, DW Morgens, LR Hayes, S Lee, B Portz, ... Neuron 104 (5), 885-898. e8, 2019 | 135 | 2019 |
| Partial inhibition of the overactivated Ku80-dependent DNA repair pathway rescues neurodegeneration in C9ORF72-ALS/FTD R Lopez-Gonzalez, D Yang, M Pribadi, TS Kim, G Krishnan, SY Choi, ... Proceedings of the National Academy of Sciences 116 (19), 9628-9633, 2019 | 82 | 2019 |
| Inhibition of JNK/dFOXO pathway and caspases rescues neurological impairments in Drosophila Alzheimer’s disease model YK Hong, S Lee, SH Park, JH Lee, SY Han, ST Kim, YK Kim, S Jeon, ... Biochemical and biophysical research communications 419 (1), 49-53, 2012 | 71 | 2012 |
| In vivo screening of traditional medicinal plants for neuroprotective activity against Aβ42 cytotoxicity by using Drosophila models of Alzheimer’s disease QF Liu, JH Lee, YM Kim, S Lee, YK Hong, S Hwang, Y Oh, K Lee, HS Yun, ... Biological and Pharmaceutical Bulletin 38 (12), 1891-1901, 2015 | 68 | 2015 |
| Drosophila DJ-1 Decreases Neural Sensitivity to Stress by Negatively Regulating Daxx-Like Protein through dFOXO S Hwang, S Song, YK Hong, G Choi, YS Suh, SY Han, M Lee, SH Park, ... PLoS genetics 9 (4), e1003412, 2013 | 67 | 2013 |
| Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM AB Loveland, E Svidritskiy, D Susorov, S Lee, A Park, S Zvornicanin, ... Nature communications 13 (1), 2776, 2022 | 62 | 2022 |
| Neuroprotective effect of SuHeXiang Wan in Drosophila models of Alzheimer's disease YK Hong, SH Park, S Lee, S Hwang, MJ Lee, D Kim, JH Lee, SY Han, ... Journal of ethnopharmacology 134 (3), 1028-1032, 2011 | 59 | 2011 |
| The effects of hempseed meal intake and linoleic acid on Drosophila models of neurodegenerative diseases and hypercholesterolemia MJ Lee, SH Park, JH Han, YK Hong, S Hwang, S Lee, D Kim, SY Han, ... Molecules and Cells 31 (4), 337-342, 2011 | 53 | 2011 |
| Evaluation of Traditional Medicines for Neurodegenerative Diseases Using Drosophila Models S Lee, SM Bang, JW Lee, KS Cho Evidence‐Based Complementary and Alternative Medicine 2014 (1), 967462, 2014 | 40 | 2014 |
| Suppressive effects of SuHeXiang Wan on amyloid-β42-induced extracellular signal-regulated kinase hyperactivation and glial cell proliferation in a transgenic Drosophila model … SH Park, S Lee, YK Hong, S Hwang, JH Lee, SM Bang, YK Kim, BS Koo, ... Biological and Pharmaceutical Bulletin 36 (3), 390-398, 2013 | 36 | 2013 |
| Remodeling of heterochromatin structure slows neuropathological progression and prolongs survival in an animal model of Huntington’s disease J Lee, YJ Hwang, Y Kim, MY Lee, SJ Hyeon, S Lee, DH Kim, SJ Jang, ... Acta neuropathologica 134 (5), 729-748, 2017 | 33 | 2017 |
| The calcineurin inhibitor Sarah (Nebula) exacerbates Aβ42 phenotypes in a Drosophila model of Alzheimer's disease S Lee, SM Bang, YK Hong, JH Lee, H Jeong, SH Park, QF Liu, IS Lee, ... Disease Models & Mechanisms 9 (3), 295-306, 2016 | 32 | 2016 |
| Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly (GR)-induced neurotoxicity in C9ORF72-ALS/FTD S Lee, YW Jun, GR Linares, B Butler, Y Yuva-Adyemir, J Moore, ... Neuron 111 (9), 1381-1390. e6, 2023 | 15 | 2023 |
| Phenotypic differences between Drosophila Alzheimer’s disease models expressing human Aβ42 in the developing eye and brain Y Jeon, S Lee, M Shin, JH Lee, YS Suh, S Hwang, HS Yun, KS Cho Animal Cells and Systems 21 (3), 160-168, 2017 | 14 | 2017 |
| Tsp66E, the Drosophila KAI1 homologue, and Tsp74F function to regulate ovarian follicle cell and wing development by stabilizing integrin localization SY Han, M Lee, YK Hong, S Hwang, G Choi, YS Suh, SH Park, S Lee, ... FEBS letters 586 (22), 4031-4037, 2012 | 13 | 2012 |
| Translation of dipeptide repeat proteins in C9ORF72 ALS/FTD through unique and redundant AUG initiation codons Y Sonobe, S Lee, G Krishnan, Y Gu, DY Kwon, FB Gao, RP Roos, ... Elife 12, e83189, 2023 | 6 | 2023 |
| Emerging roles of antimicrobial peptides in innate immunity, neuronal function, and neurodegeneration S Lee, N Silverman, FB Gao Trends in Neurosciences, 2024 | 3 | 2024 |
| Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis YW Jun, S Lee, BK Ban, JA Lee, FB Gao Autophagy 19 (7), 2045-2061, 2023 | 3 | 2023 |
| Roles of Tsp66E and Tsp74F in border cell migration and the maintenance of border cell adhesion in Drosophila H Jeong, SY Han, M Lee, S Lee, M Shin, Y Jeon, K Lee, KS Cho Genes & Genomics 37, 559-565, 2015 | 3 | 2015 |
| Effects of sarah/nebula knockdown on Aβ42-induced phenotypes during Drosophila development SM Bang, S Lee, H Jeong, YK Hong, JH Lee, S Hwang, YS Suh, K Lee, ... Genes & Genomics 38, 479-487, 2016 | 2 | 2016 |
