Human β-defensins M Pazgier, DM Hoover, D Yang, W Lu, J Lubkowski Cellular and Molecular Life Sciences CMLS 63, 1294-1313, 2006 | 737 | 2006 |
Human α-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets H Chu, M Pazgier, G Jung, SP Nuccio, PA Castillo, MF De Jong, ... Science 337 (6093), 477-481, 2012 | 445 | 2012 |
Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX M Pazgier, M Liu, G Zou, W Yuan, C Li, C Li, J Li, J Monbo, D Zella, ... Proceedings of the National Academy of Sciences 106 (12), 4665-4670, 2009 | 438 | 2009 |
D-peptide inhibitors of the p53–MDM2 interaction for targeted molecular therapy of malignant neoplasms M Liu, C Li, M Pazgier, C Li, Y Mao, Y Lv, B Gu, G Wei, W Yuan, C Zhan, ... Proceedings of the National Academy of Sciences 107 (32), 14321-14326, 2010 | 254 | 2010 |
Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy I Ullah, J Prévost, MS Ladinsky, H Stone, M Lu, SP Anand, ... Immunity 54 (9), 2143-2158. e15, 2021 | 195 | 2021 |
Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding Y Guan, M Pazgier, MM Sajadi, R Kamin-Lewis, S Al-Darmarki, R Flinko, ... Proceedings of the National Academy of Sciences 110 (1), E69-E78, 2013 | 175 | 2013 |
Systematic mutational analysis of peptide inhibition of the p53–MDM2/MDMX interactions C Li, M Pazgier, C Li, W Yuan, M Liu, G Wei, WY Lu, W Lu Journal of molecular biology 398 (2), 200-213, 2010 | 171 | 2010 |
Toward understanding the cationicity of defensins: Arg and Lys versus their noncoded analogs G Zou, E de Leeuw, C Li, M Pazgier, C Li, P Zeng, WY Lu, J Lubkowski, ... Journal of biological chemistry 282 (27), 19653-19665, 2007 | 159 | 2007 |
CD4 mimetics sensitize HIV-1-infected cells to ADCC J Richard, M Veillette, N Brassard, SS Iyer, M Roger, L Martin, M Pazgier, ... Proceedings of the National Academy of Sciences 112 (20), E2687-E2694, 2015 | 144 | 2015 |
Structural definition of an antibody-dependent cellular cytotoxicity response implicated in reduced risk for HIV-1 infection P Acharya, WD Tolbert, N Gohain, X Wu, L Yu, T Liu, W Huang, C Huang, ... Journal of virology 88 (21), 12895-12906, 2014 | 123 | 2014 |
A left handed solution to peptide inhibition of the p53-MDM2 interaction M Liu, M Pazgier, C Li, W Yuan, C Li, W Lu Angewandte Chemie (International ed. in English) 49 (21), 3649, 2010 | 121 | 2010 |
Through the looking glass, mechanistic insights from enantiomeric human defensins G Wei, E de Leeuw, M Pazgier, W Yuan, G Zou, J Wang, B Ericksen, ... Journal of Biological Chemistry 284 (42), 29180-29192, 2009 | 121 | 2009 |
Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern W Li, Y Chen, J Prévost, I Ullah, M Lu, SY Gong, A Tauzin, R Gasser, ... Cell reports 38 (2), 2022 | 111 | 2022 |
A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection G Beaudoin-Bussières, Y Chen, I Ullah, J Prévost, WD Tolbert, K Symmes, ... Cell reports 38 (7), 2022 | 107 | 2022 |
An asymmetric opening of HIV-1 envelope mediates antibody-dependent cellular cytotoxicity N Alsahafi, N Bakouche, M Kazemi, J Richard, S Ding, S Bhattacharyya, ... Cell host & microbe 25 (4), 578-587. e5, 2019 | 103 | 2019 |
Epitope specificity of human immunodeficiency virus-1 antibody dependent cellular cytotoxicity [ADCC] responses J Pollara, M Bonsignori, M Anthony Moody, M Pazgier, B F Haynes, ... Current HIV research 11 (5), 378-387, 2013 | 103 | 2013 |
Human defensins: synthesis and structural properties M Pazgier, X Li, W Lu, J Lubkowski Current pharmaceutical design 13 (30), 3096-3118, 2007 | 102 | 2007 |
Identification of near-pan-neutralizing antibodies against HIV-1 by deconvolution of plasma humoral responses MM Sajadi, A Dashti, ZR Tehrani, WD Tolbert, MS Seaman, X Ouyang, ... Cell 173 (7), 1783-1795. e14, 2018 | 101 | 2018 |
Limitations of peptide retro-inverso isomerization in molecular mimicry C Li, M Pazgier, J Li, C Li, M Liu, G Zou, Z Li, J Chen, SG Tarasov, WY Lu, ... Journal of Biological Chemistry 285 (25), 19572-19581, 2010 | 99 | 2010 |
Apamin as a novel template for structure-based rational design of potent peptide activators of p53 C Li, M Pazgier, M Liu, WY Lu, W Lu Angewandte Chemie (International ed. in English) 48 (46), 8712, 2009 | 94 | 2009 |